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Fabrication of a biocompatible flexible electroosmosis micropump

Amir Jahanshahi UGent, Fabrice Axisa UGent and Jan Vanfleteren UGent (2012) MICROFLUIDICS AND NANOFLUIDICS. 12(5). p.771-777
abstract
In in-vivo microsystems, one of the components is a biocompatible micropump in order to produce the necessary force to deliver the fluid from the inlet to the outlet. In this contribution, a flexible micropump is fabricated which is aimed to be suitable in drug delivery applications. It provides high degree of biocompatibility, since the only employed materials are implantation grade polydimethylsiloxane elastomer and gold for the electrical interconnects. The working principle of the micropump is based on transverse DC electroosmosis which is a new variant of conventionally applied high voltage DC electroosmosis. This new technique is based on topography irregularities introduced in the channel resulting in a non-uniform charge distribution. The advantage is to drive the micropump using a relatively low DC voltage of 10 V while getting an effective flow speed of 60 μm/s. In order to characterize the flow speed, dyed 3 μm beads are dispersed in the working fluid and their speed is measured by the line scanning technique using a confocal microscope. It is also observed that the flow has a helical profile which is an attractive feature for an efficient micro-mixer in active microfluidics and μ-TAS applications.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
DRUG-DELIVERY, LOW-POWER, MICROFLUIDIC DEVICES, POLY(DIMETHYLSILOXANE), CHARGE, PDMS, Micropump, Implantation, Osmosis
journal title
MICROFLUIDICS AND NANOFLUIDICS
Microfluid. Nanofluid.
volume
12
issue
5
pages
771 - 777
Web of Science type
Article
Web of Science id
000300670200010
JCR category
INSTRUMENTS & INSTRUMENTATION
JCR impact factor
3.218 (2012)
JCR rank
4/57 (2012)
JCR quartile
1 (2012)
ISSN
1613-4982
DOI
10.1007/s10404-011-0905-3
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1966955
handle
http://hdl.handle.net/1854/LU-1966955
date created
2011-12-14 11:17:56
date last changed
2012-10-26 13:46:34
@article{1966955,
  abstract     = {In in-vivo microsystems, one of the components is a biocompatible micropump in order to produce the necessary force to deliver the fluid from the inlet to the outlet. In this contribution, a flexible micropump is fabricated which is aimed to be suitable in drug delivery applications. It provides high degree of biocompatibility, since the only employed materials are implantation grade polydimethylsiloxane elastomer and gold for the electrical interconnects. The working principle of the micropump is based on transverse DC electroosmosis which is a new variant of conventionally applied high voltage DC electroosmosis. This new technique is based on topography irregularities introduced in the channel resulting in a non-uniform charge distribution. The advantage is to drive the micropump using a relatively low DC voltage of 10 V while getting an effective flow speed of 60 \ensuremath{\mu}m/s. In order to characterize the flow speed, dyed 3 \ensuremath{\mu}m beads are dispersed in the working fluid and their speed is measured by the line scanning technique using a confocal microscope. It is also observed that the flow has a helical profile which is an attractive feature for an efficient micro-mixer in active microfluidics and \ensuremath{\mu}-TAS applications.},
  author       = {Jahanshahi, Amir and Axisa, Fabrice and Vanfleteren, Jan},
  issn         = {1613-4982},
  journal      = {MICROFLUIDICS AND NANOFLUIDICS},
  keyword      = {DRUG-DELIVERY,LOW-POWER,MICROFLUIDIC DEVICES,POLY(DIMETHYLSILOXANE),CHARGE,PDMS,Micropump,Implantation,Osmosis},
  language     = {eng},
  number       = {5},
  pages        = {771--777},
  title        = {Fabrication of a biocompatible flexible electroosmosis micropump},
  url          = {http://dx.doi.org/10.1007/s10404-011-0905-3},
  volume       = {12},
  year         = {2012},
}

Chicago
Jahanshahi, Amir, Fabrice Axisa, and Jan Vanfleteren. 2012. “Fabrication of a Biocompatible Flexible Electroosmosis Micropump.” Microfluidics and Nanofluidics 12 (5): 771–777.
APA
Jahanshahi, A., Axisa, F., & Vanfleteren, J. (2012). Fabrication of a biocompatible flexible electroosmosis micropump. MICROFLUIDICS AND NANOFLUIDICS, 12(5), 771–777.
Vancouver
1.
Jahanshahi A, Axisa F, Vanfleteren J. Fabrication of a biocompatible flexible electroosmosis micropump. MICROFLUIDICS AND NANOFLUIDICS. 2012;12(5):771–7.
MLA
Jahanshahi, Amir, Fabrice Axisa, and Jan Vanfleteren. “Fabrication of a Biocompatible Flexible Electroosmosis Micropump.” MICROFLUIDICS AND NANOFLUIDICS 12.5 (2012): 771–777. Print.