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The human keratinocyte two-dimensional gel protein database: update 1993

(1993) ELECTROPHORESIS. 14(11). p.1091-1197
Author
Organization
Abstract
The master two-dimensional gel database of human keratinocytes currently lists 3038 cellular proteins (2127 isoelectric focusing, IEF; and 911 nonequilibrium pH gradient electrophoresis, NEPHGE) many of which correspond to post-translational modifications. 763 proteins have been identified (protein name, organelle components, etc.) and they are listed both in alphabetical order and with increasing SSP number, together with their M(r), pI, cellular localization and credit to the investigator(s) that aided in the identification. Furthermore we have listed 176 proteins that have been microsequenced so far and that are recorded in this database. We also include synthetic images depicting some interesting sets of proteins identified so far; these include components of hnRNP's, proteasomes or prosomes, ribosomes, as well as assorted organelle markers, GTP-binding proteins, calcium binding proteins, stress proteins, autoantigens, differentiation markers and psoriasis upregulated proteins. The aim of the comprehensive database is to gather, through a systematic study of keratinocytes, qualitative and quantitative information on proteins and their genes that may allow us to identify abnormal patterns of gene expression and ultimately to pinpoint signaling pathways and components affected in various skin diseases, cancer included.
Keywords
HUMAN EPIDERMAL-KERATINOCYTES, CELL-SURFACE RECEPTORS, DNA-SEQUENCE DATA, TERMINAL DIFFERENTIATION, EXTRACELLULAR-MATRIX, PSORIATIC SKIN, MOLECULAR-CLONING, HUMAN FIBROBLAST, ELECTROPHORESIS, EXPRESSION

Citation

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Chicago
Celis, Julio E, Hanne Holm Rasmussen, Eydfinnur Olsen, Peder Madsen, Henrik Leffers, Bent Honoré, Kurt Dejgaard, et al. 1993. “The Human Keratinocyte Two-dimensional Gel Protein Database: Update 1993.” Electrophoresis 14 (11): 1091–1197.
APA
Celis, J. E., Rasmussen, H. H., Olsen, E., Madsen, P., Leffers, H., Honoré, B., Dejgaard, K., et al. (1993). The human keratinocyte two-dimensional gel protein database: update 1993. ELECTROPHORESIS, 14(11), 1091–1197.
Vancouver
1.
Celis JE, Rasmussen HH, Olsen E, Madsen P, Leffers H, Honoré B, et al. The human keratinocyte two-dimensional gel protein database: update 1993. ELECTROPHORESIS. 1993;14(11):1091–197.
MLA
Celis, Julio E, Hanne Holm Rasmussen, Eydfinnur Olsen, et al. “The Human Keratinocyte Two-dimensional Gel Protein Database: Update 1993.” ELECTROPHORESIS 14.11 (1993): 1091–1197. Print.
@article{196465,
  abstract     = {The master two-dimensional gel database of human keratinocytes currently lists 3038 cellular proteins (2127 isoelectric focusing, IEF; and 911 nonequilibrium pH gradient electrophoresis, NEPHGE) many of which correspond to post-translational modifications. 763 proteins have been identified (protein name, organelle components, etc.) and they are listed both in alphabetical order and with increasing SSP number, together with their M(r), pI, cellular localization and credit to the investigator(s) that aided in the identification. Furthermore we have listed 176 proteins that have been microsequenced so far and that are recorded in this database. We also include synthetic images depicting some interesting sets of proteins identified so far; these include components of hnRNP's, proteasomes or prosomes, ribosomes, as well as assorted organelle markers, GTP-binding proteins, calcium binding proteins, stress proteins, autoantigens, differentiation markers and psoriasis upregulated proteins. The aim of the comprehensive database is to gather, through a systematic study of keratinocytes, qualitative and quantitative information on proteins and their genes that may allow us to identify abnormal patterns of gene expression and ultimately to pinpoint signaling pathways and components affected in various skin diseases, cancer included.},
  author       = {Celis, Julio E and Rasmussen, Hanne Holm and Olsen, Eydfinnur and Madsen, Peder and Leffers, Henrik and Honor{\'e}, Bent and Dejgaard, Kurt and Gromov, Paul and Hoffmann, Hans J{\"u}rgen and Nielsen, Morten and Vassilev, Alex and Vintermyr, Olav and Hao, Junshan and Celis, Ariana and Basse, Bodil and Lauridsen, Jette B and Ratz, Gitte P and Andersen, Annette H and Walbum, Else and Kj{\ae}rgaard, Inge and Puype, Magda and Van Damme, Jozef and Vandekerckhove, Jo{\"e}l},
  issn         = {0173-0835},
  journal      = {ELECTROPHORESIS},
  keyword      = {HUMAN EPIDERMAL-KERATINOCYTES,CELL-SURFACE RECEPTORS,DNA-SEQUENCE DATA,TERMINAL DIFFERENTIATION,EXTRACELLULAR-MATRIX,PSORIATIC SKIN,MOLECULAR-CLONING,HUMAN FIBROBLAST,ELECTROPHORESIS,EXPRESSION},
  language     = {eng},
  number       = {11},
  pages        = {1091--1197},
  title        = {The human keratinocyte two-dimensional gel protein database: update 1993},
  url          = {http://dx.doi.org/10.1002/elps.11501401178},
  volume       = {14},
  year         = {1993},
}

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