A chemoenzymatic synthesis of A-ring key-intermediates for 1-α,25-dihydroxyvitamin D3 and analogs
- Author
- Sara Vrielynck, Maurits Vandewalle, Ana M. García, José L. Mascareñas and Antonio Mouriñio
- Organization
- Abstract
- A short and practical synthesis of the 1,7-enyne A-ring intermediate and of Uskokovic’s phosphine-oxide precursor is described starting from the aldol product of acrolein with t-butyl acetate. Enantiopure β-hydroxy ester is obtained upon lipase-catalyzed resolution.
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-196249
- MLA
- Vrielynck, Sara, et al. “A Chemoenzymatic Synthesis of A-Ring Key-Intermediates for 1-α,25-Dihydroxyvitamin D3 and Analogs.” TETRAHEDRON LETTERS, vol. 36, no. 49, 1995, pp. 9023–26.
- APA
- Vrielynck, S., Vandewalle, M., García, A. M., Mascareñas, J. L., & Mouriñio, A. (1995). A chemoenzymatic synthesis of A-ring key-intermediates for 1-α,25-dihydroxyvitamin D3 and analogs. TETRAHEDRON LETTERS, 36(49), 9023–9026.
- Chicago author-date
- Vrielynck, Sara, Maurits Vandewalle, Ana M. García, José L. Mascareñas, and Antonio Mouriñio. 1995. “A Chemoenzymatic Synthesis of A-Ring Key-Intermediates for 1-α,25-Dihydroxyvitamin D3 and Analogs.” TETRAHEDRON LETTERS 36 (49): 9023–26.
- Chicago author-date (all authors)
- Vrielynck, Sara, Maurits Vandewalle, Ana M. García, José L. Mascareñas, and Antonio Mouriñio. 1995. “A Chemoenzymatic Synthesis of A-Ring Key-Intermediates for 1-α,25-Dihydroxyvitamin D3 and Analogs.” TETRAHEDRON LETTERS 36 (49): 9023–9026.
- Vancouver
- 1.Vrielynck S, Vandewalle M, García AM, Mascareñas JL, Mouriñio A. A chemoenzymatic synthesis of A-ring key-intermediates for 1-α,25-dihydroxyvitamin D3 and analogs. TETRAHEDRON LETTERS. 1995;36(49):9023–6.
- IEEE
- [1]S. Vrielynck, M. Vandewalle, A. M. García, J. L. Mascareñas, and A. Mouriñio, “A chemoenzymatic synthesis of A-ring key-intermediates for 1-α,25-dihydroxyvitamin D3 and analogs,” TETRAHEDRON LETTERS, vol. 36, no. 49, pp. 9023–9026, 1995.
@article{196249, abstract = {{A short and practical synthesis of the 1,7-enyne A-ring intermediate and of Uskokovic’s phosphine-oxide precursor is described starting from the aldol product of acrolein with t-butyl acetate. Enantiopure β-hydroxy ester is obtained upon lipase-catalyzed resolution.}}, author = {{Vrielynck, Sara and Vandewalle, Maurits and García, Ana M. and Mascareñas, José L. and Mouriñio, Antonio}}, issn = {{0040-4039}}, journal = {{TETRAHEDRON LETTERS}}, language = {{eng}}, number = {{49}}, pages = {{9023--9026}}, title = {{A chemoenzymatic synthesis of A-ring key-intermediates for 1-α,25-dihydroxyvitamin D3 and analogs}}, volume = {{36}}, year = {{1995}}, }