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Studies directed towards the total synthesis of (±)-himbacine

Govert De Baecke and Pierre De Clercq (UGent)
(1995) TETRAHEDRON LETTERS. 36(41). p.7515-7518
Author
Organization
Abstract
The synthesis of aldehyde 11a is reported based upon the intramolecular Diels-Alder reaction of triene 10, the butenolide-diene part of which was obtained in one step via the condensation of the enolate derived from the (Z)-enoate ester 5 with 2-acetoxypropanal. Aldehyde 11a possesses the correct stereochemistry of the tricyclic part of himbacine, an important muscarine receptor antagonist.
Keywords
DIELS-ALDER REACTION, MUSCARINIC RECEPTORS, HIMBACINE, BINDING

Citation

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MLA
De Baecke, Govert, and Pierre De Clercq. “Studies Directed towards the Total Synthesis of (±)-Himbacine.” TETRAHEDRON LETTERS, vol. 36, no. 41, 1995, pp. 7515–18, doi:10.1016/0040-4039(95)01520-5.
APA
De Baecke, G., & De Clercq, P. (1995). Studies directed towards the total synthesis of (±)-himbacine. TETRAHEDRON LETTERS, 36(41), 7515–7518. https://doi.org/10.1016/0040-4039(95)01520-5
Chicago author-date
De Baecke, Govert, and Pierre De Clercq. 1995. “Studies Directed towards the Total Synthesis of (±)-Himbacine.” TETRAHEDRON LETTERS 36 (41): 7515–18. https://doi.org/10.1016/0040-4039(95)01520-5.
Chicago author-date (all authors)
De Baecke, Govert, and Pierre De Clercq. 1995. “Studies Directed towards the Total Synthesis of (±)-Himbacine.” TETRAHEDRON LETTERS 36 (41): 7515–7518. doi:10.1016/0040-4039(95)01520-5.
Vancouver
1.
De Baecke G, De Clercq P. Studies directed towards the total synthesis of (±)-himbacine. TETRAHEDRON LETTERS. 1995;36(41):7515–8.
IEEE
[1]
G. De Baecke and P. De Clercq, “Studies directed towards the total synthesis of (±)-himbacine,” TETRAHEDRON LETTERS, vol. 36, no. 41, pp. 7515–7518, 1995.
@article{195613,
  abstract     = {{The synthesis of aldehyde 11a is reported based upon the intramolecular Diels-Alder reaction of triene 10, the butenolide-diene part of which was obtained in one step via the condensation of the enolate derived from the (Z)-enoate ester 5 with 2-acetoxypropanal. Aldehyde 11a possesses the correct stereochemistry of the tricyclic part of himbacine, an important muscarine receptor antagonist.}},
  author       = {{De Baecke, Govert and De Clercq, Pierre}},
  issn         = {{0040-4039}},
  journal      = {{TETRAHEDRON LETTERS}},
  keywords     = {{DIELS-ALDER REACTION,MUSCARINIC RECEPTORS,HIMBACINE,BINDING}},
  language     = {{eng}},
  number       = {{41}},
  pages        = {{7515--7518}},
  title        = {{Studies directed towards the total synthesis of (±)-himbacine}},
  url          = {{http://doi.org/10.1016/0040-4039(95)01520-5}},
  volume       = {{36}},
  year         = {{1995}},
}
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