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Severe lameness caused by metastatic renal adenocarcinoma of the third phalanx in a Warmblood mare

Maarten Oosterlinck UGent, Els Raes UGent, Stephanie Verbraecken UGent, Gunther van Loon UGent, S Maes, Ingrid Gielen UGent, Laurence Lefère UGent and Jimmy Saunders UGent (2011) EQUINE VETERINARY EDUCATION. 23(10). p.512-516
abstract
Malignant osseous neoplasia has been extremely rarely reported in the horse and, therefore, it is not commonly considered as a differential diagnosis for acute lameness. In the present report, a 19-year-old Warmblood mare in poor body condition and with a history of chronic haematuria, presumably attributable to renal neoplasia, was referred with acute, progressive, unilateral right forelimb lameness with marked unilateral digital pulsation and metacarpal oedema. No hoof abscess was found. Radiographic examination revealed a well defined osteolytic area in the dorsomedial half of the third phalanx. Dermal laminae at the dorsomedial aspect of the hoof showed a dark red appearance with poor vascularisation. Thoracic radiographs revealed pulmonary nodules. As osseous metastasis of the third phalanx was suspected, the mare was subjected to euthanasia. Post mortem histopathological examination confirmed the diagnosis of primary renal adenocarcinoma with metastasis to the lungs, myocardium, along the perirenal lymphatic tract and to the third phalanx, with extensive osteolysis in the latter location. Post mortem computed tomography of the hoof provided excellent visualisation of the osseous metastasis. The rare possibility of osseous metastatic neoplasia should be included in the differential diagnosis of severe lameness, especially in aged horses with a history of chronic renal disease.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
neoplasia, metastasis, CELL CARCINOMA, HORSE, OSTEOSARCOMA, NEOPLASIA, kidney, hoof, bone, horse
journal title
EQUINE VETERINARY EDUCATION
Equine Vet. Educ.
volume
23
issue
10
pages
512 - 516
Web of Science type
Article
Web of Science id
000294808500007
JCR category
VETERINARY SCIENCES
JCR impact factor
0.545 (2011)
JCR rank
88/141 (2011)
JCR quartile
3 (2011)
ISSN
0957-7734
DOI
10.1111/j.2042-3292.2011.00282.x
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1947718
handle
http://hdl.handle.net/1854/LU-1947718
date created
2011-11-23 11:47:48
date last changed
2011-11-24 16:14:24
@article{1947718,
  abstract     = {Malignant osseous neoplasia has been extremely rarely reported in the horse and, therefore, it is not commonly considered as a differential diagnosis for acute lameness. In the present report, a 19-year-old Warmblood mare in poor body condition and with a history of chronic haematuria, presumably attributable to renal neoplasia, was referred with acute, progressive, unilateral right forelimb lameness with marked unilateral digital pulsation and metacarpal oedema. No hoof abscess was found. Radiographic examination revealed a well defined osteolytic area in the dorsomedial half of the third phalanx. Dermal laminae at the dorsomedial aspect of the hoof showed a dark red appearance with poor vascularisation. Thoracic radiographs revealed pulmonary nodules. As osseous metastasis of the third phalanx was suspected, the mare was subjected to euthanasia. Post mortem histopathological examination confirmed the diagnosis of primary renal adenocarcinoma with metastasis to the lungs, myocardium, along the perirenal lymphatic tract and to the third phalanx, with extensive osteolysis in the latter location. Post mortem computed tomography of the hoof provided excellent visualisation of the osseous metastasis. The rare possibility of osseous metastatic neoplasia should be included in the differential diagnosis of severe lameness, especially in aged horses with a history of chronic renal disease.},
  author       = {Oosterlinck, Maarten and Raes, Els and Verbraecken, Stephanie and van Loon, Gunther and Maes, S and Gielen, Ingrid and Lef{\`e}re, Laurence and Saunders, Jimmy},
  issn         = {0957-7734},
  journal      = {EQUINE VETERINARY EDUCATION},
  keyword      = {neoplasia,metastasis,CELL CARCINOMA,HORSE,OSTEOSARCOMA,NEOPLASIA,kidney,hoof,bone,horse},
  language     = {eng},
  number       = {10},
  pages        = {512--516},
  title        = {Severe lameness caused by metastatic renal adenocarcinoma of the third phalanx in a Warmblood mare},
  url          = {http://dx.doi.org/10.1111/j.2042-3292.2011.00282.x},
  volume       = {23},
  year         = {2011},
}

Chicago
Oosterlinck, Maarten, Els Raes, Stephanie Verbraecken, Gunther van Loon, S Maes, Ingrid Gielen, Laurence Lefère, and Jimmy Saunders. 2011. “Severe Lameness Caused by Metastatic Renal Adenocarcinoma of the Third Phalanx in a Warmblood Mare.” Equine Veterinary Education 23 (10): 512–516.
APA
Oosterlinck, M., Raes, E., Verbraecken, S., van Loon, G., Maes, S., Gielen, I., Lefère, L., et al. (2011). Severe lameness caused by metastatic renal adenocarcinoma of the third phalanx in a Warmblood mare. EQUINE VETERINARY EDUCATION, 23(10), 512–516.
Vancouver
1.
Oosterlinck M, Raes E, Verbraecken S, van Loon G, Maes S, Gielen I, et al. Severe lameness caused by metastatic renal adenocarcinoma of the third phalanx in a Warmblood mare. EQUINE VETERINARY EDUCATION. 2011;23(10):512–6.
MLA
Oosterlinck, Maarten, Els Raes, Stephanie Verbraecken, et al. “Severe Lameness Caused by Metastatic Renal Adenocarcinoma of the Third Phalanx in a Warmblood Mare.” EQUINE VETERINARY EDUCATION 23.10 (2011): 512–516. Print.