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Simultaneous determination of artemisinin and its bioprecursors in Artemisia annua

Dirk Vandenberghe (UGent) , Annemieke Vergauwe (UGent) , Marc Van Montagu (UGent) and Elfrida Van Den Eeckhout
(1995) JOURNAL OF NATURAL PRODUCTS. 58(5). p.798-803
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Abstract
Artemisia annua has been used for the treatment of fever and malaria. Artemisinin [1], a sesquiterpene lactone constituent of this plane, is responsible for its therapeutic effects. A rapid, sensitive, and specific reversed-phase hplc method using electrochemical and uv detection has been developed for the simultaneous determination in plant extracts of 1 and its bioprecursors artemisinic acid [2], arteannuin B [3], and artemisitene [4].
Keywords
ABSORPTION, DIHYDROARTEMISININ, PLASMA, CHEMICAL DERIVATIZATION, PERFORMANCE LIQUID-CHROMATOGRAPHY, QINGHAOSU, ACID, GAS-CHROMATOGRAPHY, ANTIMALARIAL DRUG, BIOSYNTHESIS

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Chicago
Vandenberghe, Dirk, Annemieke Vergauwe, Marc Van Montagu, and Elfrida Van Den Eeckhout. 1995. “Simultaneous Determination of Artemisinin and Its Bioprecursors in Artemisia Annua.” Journal of Natural Products 58 (5): 798–803.
APA
Vandenberghe, Dirk, Vergauwe, A., Van Montagu, M., & Van Den Eeckhout, E. (1995). Simultaneous determination of artemisinin and its bioprecursors in Artemisia annua. JOURNAL OF NATURAL PRODUCTS, 58(5), 798–803.
Vancouver
1.
Vandenberghe D, Vergauwe A, Van Montagu M, Van Den Eeckhout E. Simultaneous determination of artemisinin and its bioprecursors in Artemisia annua. JOURNAL OF NATURAL PRODUCTS. 1995;58(5):798–803.
MLA
Vandenberghe, Dirk, Annemieke Vergauwe, Marc Van Montagu, et al. “Simultaneous Determination of Artemisinin and Its Bioprecursors in Artemisia Annua.” JOURNAL OF NATURAL PRODUCTS 58.5 (1995): 798–803. Print.
@article{194372,
  abstract     = {Artemisia annua has been used for the treatment of fever and malaria. Artemisinin [1], a sesquiterpene lactone constituent of this plane, is responsible for its therapeutic effects. A rapid, sensitive, and specific reversed-phase hplc method using electrochemical and uv detection has been developed for the simultaneous determination in plant extracts of 1 and its bioprecursors artemisinic acid [2], arteannuin B [3], and artemisitene [4].},
  author       = {Vandenberghe, Dirk and Vergauwe, Annemieke and Van Montagu, Marc and Van Den Eeckhout, Elfrida},
  issn         = {0163-3864},
  journal      = {JOURNAL OF NATURAL PRODUCTS},
  language     = {eng},
  number       = {5},
  pages        = {798--803},
  title        = {Simultaneous determination of artemisinin and its bioprecursors in Artemisia annua},
  url          = {http://dx.doi.org/10.1021/np50119a027},
  volume       = {58},
  year         = {1995},
}
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