The 10-word learning task in the differential diagnosis of early Alzheimer's disease and elderly depression: a cross-sectional pilot study
- Author
- Eva Dierckx, Sebastiaan Engelborghs, Rudi De Raedt (UGent) , Peter Paul De Deyn, Ellen D'Haenens, Dominique Verte and Ingrid Ponjaert-Kristoffersen
- Organization
- Abstract
- Objectives: Identification of early Alzheimer's disease (AD) has become very important. Episodic memory tasks appear to have predictive power for indicating early AD. Deficits in encoding and storage processes that are characteristic of AD, however, must be distinguished from non-AD deficits that can also affect memory, including difficulties that may be present in depression. This pilot study was set up to ascertain whether a 10-word-list-learning task (delayed recognition and rate of forgetting) may be useful in making the differentiation between mild AD and depression. Method: A Dutch version of Rey's auditory verbal learning test was administered to 36 mild AD patients, 41 depressed patients, and 47 healthy controls. Data were analyzed in a cross-sectional manner. Results: Receiver operating characteristic analyses showed that for differentiating mild AD and depression, both delayed recognition and percentage of forgetting have sufficient diagnostic accuracy. Conclusion: Percentage of forgetting had the highest diagnostic accuracy for differentiating mild AD and depressed patients and may be useful in the early detection of AD.
- Keywords
- MEMORY IMPAIRMENT, MILD COGNITIVE IMPAIRMENT, DEMENTIA, ASSOCIATION, PERFORMANCE, DISORDERS, UNIPOLAR, IMPROVE, TESTS, SCALE, dementia, elderly depression, memory, recognition, delayed recall, serial verbal learning test
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-1940857
- MLA
- Dierckx, Eva, et al. “The 10-Word Learning Task in the Differential Diagnosis of Early Alzheimer’s Disease and Elderly Depression: A Cross-Sectional Pilot Study.” AGING & MENTAL HEALTH, vol. 15, no. 1, 2011, pp. 113–21, doi:10.1080/13607863.2010.505228.
- APA
- Dierckx, E., Engelborghs, S., De Raedt, R., De Deyn, P. P., D’Haenens, E., Verte, D., & Ponjaert-Kristoffersen, I. (2011). The 10-word learning task in the differential diagnosis of early Alzheimer’s disease and elderly depression: a cross-sectional pilot study. AGING & MENTAL HEALTH, 15(1), 113–121. https://doi.org/10.1080/13607863.2010.505228
- Chicago author-date
- Dierckx, Eva, Sebastiaan Engelborghs, Rudi De Raedt, Peter Paul De Deyn, Ellen D’Haenens, Dominique Verte, and Ingrid Ponjaert-Kristoffersen. 2011. “The 10-Word Learning Task in the Differential Diagnosis of Early Alzheimer’s Disease and Elderly Depression: A Cross-Sectional Pilot Study.” AGING & MENTAL HEALTH 15 (1): 113–21. https://doi.org/10.1080/13607863.2010.505228.
- Chicago author-date (all authors)
- Dierckx, Eva, Sebastiaan Engelborghs, Rudi De Raedt, Peter Paul De Deyn, Ellen D’Haenens, Dominique Verte, and Ingrid Ponjaert-Kristoffersen. 2011. “The 10-Word Learning Task in the Differential Diagnosis of Early Alzheimer’s Disease and Elderly Depression: A Cross-Sectional Pilot Study.” AGING & MENTAL HEALTH 15 (1): 113–121. doi:10.1080/13607863.2010.505228.
- Vancouver
- 1.Dierckx E, Engelborghs S, De Raedt R, De Deyn PP, D’Haenens E, Verte D, et al. The 10-word learning task in the differential diagnosis of early Alzheimer’s disease and elderly depression: a cross-sectional pilot study. AGING & MENTAL HEALTH. 2011;15(1):113–21.
- IEEE
- [1]E. Dierckx et al., “The 10-word learning task in the differential diagnosis of early Alzheimer’s disease and elderly depression: a cross-sectional pilot study,” AGING & MENTAL HEALTH, vol. 15, no. 1, pp. 113–121, 2011.
@article{1940857,
abstract = {{Objectives: Identification of early Alzheimer's disease (AD) has become very important. Episodic memory tasks appear to have predictive power for indicating early AD. Deficits in encoding and storage processes that are characteristic of AD, however, must be distinguished from non-AD deficits that can also affect memory, including difficulties that may be present in depression. This pilot study was set up to ascertain whether a 10-word-list-learning task (delayed recognition and rate of forgetting) may be useful in making the differentiation between mild AD and depression. Method: A Dutch version of Rey's auditory verbal learning test was administered to 36 mild AD patients, 41 depressed patients, and 47 healthy controls. Data were analyzed in a cross-sectional manner. Results: Receiver operating characteristic analyses showed that for differentiating mild AD and depression, both delayed recognition and percentage of forgetting have sufficient diagnostic accuracy. Conclusion: Percentage of forgetting had the highest diagnostic accuracy for differentiating mild AD and depressed patients and may be useful in the early detection of AD.}},
articleno = {{PII 927613040}},
author = {{Dierckx, Eva and Engelborghs, Sebastiaan and De Raedt, Rudi and De Deyn, Peter Paul and D'Haenens, Ellen and Verte, Dominique and Ponjaert-Kristoffersen, Ingrid}},
issn = {{1360-7863}},
journal = {{AGING & MENTAL HEALTH}},
keywords = {{MEMORY IMPAIRMENT,MILD COGNITIVE IMPAIRMENT,DEMENTIA,ASSOCIATION,PERFORMANCE,DISORDERS,UNIPOLAR,IMPROVE,TESTS,SCALE,dementia,elderly depression,memory,recognition,delayed recall,serial verbal learning test}},
language = {{eng}},
number = {{1}},
pages = {{PII 927613040:113--PII 927613040:121}},
title = {{The 10-word learning task in the differential diagnosis of early Alzheimer's disease and elderly depression: a cross-sectional pilot study}},
url = {{http://doi.org/10.1080/13607863.2010.505228}},
volume = {{15}},
year = {{2011}},
}
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