Advanced search
1 file | 126.63 KB Add to list

Enhanced cognitive control in young people with Tourette's syndrome

(2006) CURRENT BIOLOGY. 16(6). p.570-573
Author
Organization
Abstract
Tourette's syndrome (TS) is a neurodevelopmental disorder characterized by the presence of chronic vocal and motor tics. Tics are sudden, highly stereotyped, movements that can be simple or complex in appearance. Since patients with TS have difficulties preventing unwanted movements, one might expect that their ability to voluntarily control goal-directed movements would be similarly poor. Indeed, it has been suggested that TS sufferers are impaired at inhibiting reflexively triggered movements and in rapidly selecting or switching between different motor sets [1]. This idea is consistent with current views on the neurological basis of TS that posit a dysfunction of the neural circuits linking the frontal lobes and the striatum [2]. These circuits are known to be involved in the voluntary control of action [3, 4]. By using an oculomotor switching task, we show for the first time that young people with TS exhibit paradoxically greater levels of cognitive control over their movements than their age-matched controls. This finding is consistent with an increased need to monitor and control movements and may indicate a subcortical locus for the triggering of tics. It also suggests that the constant need to suppress tics could have resulted in an enhancement of the executive processes involved in inhibitory control.
Keywords
SET, TASKS, INHIBITION, ATTENTION, DEFICITS, DISEASE, CORTEX

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 126.63 KB

Citation

Please use this url to cite or link to this publication:

MLA
Müller, Sven, Georgina Jackson, Ranu Dhalla, et al. “Enhanced Cognitive Control in Young People with Tourette’s Syndrome.” CURRENT BIOLOGY 16.6 (2006): 570–573. Print.
APA
Müller, Sven, Jackson, G., Dhalla, R., Datsopolous, S., & Hollis, C. (2006). Enhanced cognitive control in young people with Tourette’s syndrome. CURRENT BIOLOGY, 16(6), 570–573.
Chicago author-date
Müller, Sven, Georgina Jackson, Ranu Dhalla, Sophia Datsopolous, and Chris Hollis. 2006. “Enhanced Cognitive Control in Young People with Tourette’s Syndrome.” Current Biology 16 (6): 570–573.
Chicago author-date (all authors)
Müller, Sven, Georgina Jackson, Ranu Dhalla, Sophia Datsopolous, and Chris Hollis. 2006. “Enhanced Cognitive Control in Young People with Tourette’s Syndrome.” Current Biology 16 (6): 570–573.
Vancouver
1.
Müller S, Jackson G, Dhalla R, Datsopolous S, Hollis C. Enhanced cognitive control in young people with Tourette’s syndrome. CURRENT BIOLOGY. 2006;16(6):570–3.
IEEE
[1]
S. Müller, G. Jackson, R. Dhalla, S. Datsopolous, and C. Hollis, “Enhanced cognitive control in young people with Tourette’s syndrome,” CURRENT BIOLOGY, vol. 16, no. 6, pp. 570–573, 2006.
@article{1927564,
  abstract     = {Tourette's syndrome (TS) is a neurodevelopmental disorder characterized by the presence of chronic vocal and motor tics. Tics are sudden, highly stereotyped, movements that can be simple or complex in appearance. Since patients with TS have difficulties preventing unwanted movements, one might expect that their ability to voluntarily control goal-directed movements would be similarly poor. Indeed, it has been suggested that TS sufferers are impaired at inhibiting reflexively triggered movements and in rapidly selecting or switching between different motor sets [1]. This idea is consistent with current views on the neurological basis of TS that posit a dysfunction of the neural circuits linking the frontal lobes and the striatum [2]. These circuits are known to be involved in the voluntary control of action [3, 4]. By using an oculomotor switching task, we show for the first time that young people with TS exhibit paradoxically greater levels of cognitive control over their movements than their age-matched controls. This finding is consistent with an increased need to monitor and control movements and may indicate a subcortical locus for the triggering of tics. It also suggests that the constant need to suppress tics could have resulted in an enhancement of the executive processes involved in inhibitory control.},
  author       = {Müller, Sven and Jackson, Georgina and Dhalla, Ranu and Datsopolous, Sophia and Hollis, Chris},
  issn         = {0960-9822},
  journal      = {CURRENT BIOLOGY},
  keywords     = {SET,TASKS,INHIBITION,ATTENTION,DEFICITS,DISEASE,CORTEX},
  language     = {eng},
  number       = {6},
  pages        = {570--573},
  title        = {Enhanced cognitive control in young people with Tourette's syndrome},
  url          = {http://dx.doi.org/10.1016/j.cub.2006.01.064},
  volume       = {16},
  year         = {2006},
}

Altmetric
View in Altmetric
Web of Science
Times cited: