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The pumping mechanism of embryonic hearts

Frédéric Maes UGent, Bill Chaudhry, Peter Van Ransbeeck UGent and Pascal Verdonck UGent (2012) IFMBE Proceedings. 37(5th European conference of the International Federation for Medical and Biological Engineering, pts 1 and 2). p.470-473
abstract
The embryonic heart starts pumping as a contractile tube. However its simple geometry there has been debate about how the early stage embryonic heart is actually functioning. The current model presented in Science 2006 describes it as a dynamic suction pump. According to this model the heart has one singe active contraction site, the remainder of the wall movement is through passive wall propagation. Our research however revealed more than one active contraction location. Moreover we showed that heart wall motion is closely following the calcium signal of the heart. These discoveries imply that the current model is not the correct representation of the working principle of the embryonic heart.
Please use this url to cite or link to this publication:
author
organization
year
type
conference (proceedingsPaper)
publication status
published
subject
keyword
Heart development, pumping mechanism
in
IFMBE Proceedings
IFMBE Proc.
editor
Ákos Jobbágy
volume
37
issue
5th European conference of the International Federation for Medical and Biological Engineering, pts 1 and 2
pages
470 - 473
publisher
Springer
place of publication
Berlin, Germany
conference name
5th European conference of the International Federation for Medical and Biological Engineering (IFMBE 2011)
conference location
Budapest, Hungary
conference start
2011-09-14
conference end
2011-09-14
Web of Science type
Proceedings Paper
Web of Science id
000310938200122
ISSN
1680-0737
DOI
10.1007/978-3-642-23508-5_122
language
English
UGent publication?
yes
classification
P1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1920536
handle
http://hdl.handle.net/1854/LU-1920536
date created
2011-10-04 15:20:26
date last changed
2017-01-02 09:53:00
@inproceedings{1920536,
  abstract     = {The embryonic heart starts pumping as a contractile tube. However its simple geometry there has been debate about how the early stage embryonic heart is actually functioning. The current model presented in Science 2006 describes it as a dynamic suction pump. According to this model the heart has one singe active contraction site, the remainder of the wall movement is through passive wall propagation. Our research however revealed more than one active contraction location. Moreover we showed that heart wall motion is closely following the calcium signal of the heart. These discoveries imply that the current model is not the correct representation of the working principle of the embryonic heart.},
  author       = {Maes, Fr{\'e}d{\'e}ric and Chaudhry, Bill and Van Ransbeeck, Peter and Verdonck, Pascal},
  booktitle    = {IFMBE Proceedings},
  editor       = {Jobb{\'a}gy, {\'A}kos },
  issn         = {1680-0737},
  keyword      = {Heart development,pumping mechanism},
  language     = {eng},
  location     = {Budapest, Hungary},
  number       = {5th European conference of the International Federation for Medical and Biological Engineering, pts 1 and 2},
  pages        = {470--473},
  publisher    = {Springer},
  title        = {The pumping mechanism of embryonic hearts},
  url          = {http://dx.doi.org/10.1007/978-3-642-23508-5\_122},
  volume       = {37},
  year         = {2012},
}

Chicago
Maes, Frédéric, Bill Chaudhry, Peter Van Ransbeeck, and Pascal Verdonck. 2012. “The Pumping Mechanism of Embryonic Hearts.” In IFMBE Proceedings, ed. Ákos Jobbágy, 37:470–473. Berlin, Germany: Springer.
APA
Maes, Frédéric, Chaudhry, B., Van Ransbeeck, P., & Verdonck, P. (2012). The pumping mechanism of embryonic hearts. In Á. Jobbágy (Ed.), IFMBE Proceedings (Vol. 37, pp. 470–473). Presented at the 5th European conference of the International Federation for Medical and Biological Engineering (IFMBE 2011), Berlin, Germany: Springer.
Vancouver
1.
Maes F, Chaudhry B, Van Ransbeeck P, Verdonck P. The pumping mechanism of embryonic hearts. In: Jobbágy Á, editor. IFMBE Proceedings. Berlin, Germany: Springer; 2012. p. 470–3.
MLA
Maes, Frédéric, Bill Chaudhry, Peter Van Ransbeeck, et al. “The Pumping Mechanism of Embryonic Hearts.” IFMBE Proceedings. Ed. Ákos Jobbágy. Vol. 37. Berlin, Germany: Springer, 2012. 470–473. Print.