Advanced search
Add to list

Effect of the inhalation of nitric oxide on 5-hydroxytryptamine-induced pulmonary hypertension in calves

Author
Organization
Abstract
In healthy anaesthetized Friesian-Holstein calves, pulmonary hypertension was induced ly means of a continuous intravenous administration of serotonin (0.025 mg/kg body/weight/min). Afterwards, the anaesthetized calves inhaled 40 and 80 ppm of nitric oxide using an open system. The influences of the administration of serotonin and the inhalation of nitric oxide on the haemodynamic and blood gas parameters were investigated. The inhalation of 40 and 80 ppm of nitric oxide during: serotonin-induced pulmonary hypertension in calves resulted in a significant fall of the mean pulmonary artery pressure. The inhalation of nitric oxide also induced an amelioration of intrapulmonary oxygen transport. The intravenous administration of serotonin in calves resulted in severe systemic hypotension. Hence, the influence of the inhalation of nitric oxide on the systemic arterial pressure could not be evaluated.

Citation

Please use this url to cite or link to this publication:

MLA
Sustronck, Bart, Gunther van Loon, Frank Gasthuys, et al. “Effect of the Inhalation of Nitric Oxide on 5-hydroxytryptamine-induced Pulmonary Hypertension in Calves.” JOURNAL OF VETERINARY MEDICINE SERIES A-ZENTRALBLATT FUR VETERINARMEDIZIN REIHE A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE 43.9 (1996): 513–520. Print.
APA
Sustronck, B., van Loon, G., Gasthuys, F., FOUBERT, L., Deprez, P., & Muylle, E. (1996). Effect of the inhalation of nitric oxide on 5-hydroxytryptamine-induced pulmonary hypertension in calves. JOURNAL OF VETERINARY MEDICINE SERIES A-ZENTRALBLATT FUR VETERINARMEDIZIN REIHE A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE, 43(9), 513–520.
Chicago author-date
Sustronck, Bart, Gunther van Loon, Frank Gasthuys, L FOUBERT, Piet Deprez, and Etienne Muylle. 1996. “Effect of the Inhalation of Nitric Oxide on 5-hydroxytryptamine-induced Pulmonary Hypertension in Calves.” Journal of Veterinary Medicine Series A-zentralblatt Fur Veterinarmedizin Reihe A-physiology Pathology Clinical Medicine 43 (9): 513–520.
Chicago author-date (all authors)
Sustronck, Bart, Gunther van Loon, Frank Gasthuys, L FOUBERT, Piet Deprez, and Etienne Muylle. 1996. “Effect of the Inhalation of Nitric Oxide on 5-hydroxytryptamine-induced Pulmonary Hypertension in Calves.” Journal of Veterinary Medicine Series A-zentralblatt Fur Veterinarmedizin Reihe A-physiology Pathology Clinical Medicine 43 (9): 513–520.
Vancouver
1.
Sustronck B, van Loon G, Gasthuys F, FOUBERT L, Deprez P, Muylle E. Effect of the inhalation of nitric oxide on 5-hydroxytryptamine-induced pulmonary hypertension in calves. JOURNAL OF VETERINARY MEDICINE SERIES A-ZENTRALBLATT FUR VETERINARMEDIZIN REIHE A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE. 1996;43(9):513–20.
IEEE
[1]
B. Sustronck, G. van Loon, F. Gasthuys, L. FOUBERT, P. Deprez, and E. Muylle, “Effect of the inhalation of nitric oxide on 5-hydroxytryptamine-induced pulmonary hypertension in calves,” JOURNAL OF VETERINARY MEDICINE SERIES A-ZENTRALBLATT FUR VETERINARMEDIZIN REIHE A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE, vol. 43, no. 9, pp. 513–520, 1996.
@article{191142,
  abstract     = {In healthy anaesthetized Friesian-Holstein calves, pulmonary hypertension was induced ly means of a continuous intravenous administration of serotonin (0.025 mg/kg body/weight/min). Afterwards, the anaesthetized calves inhaled 40 and 80 ppm of nitric oxide using an open system. The influences of the administration of serotonin and the inhalation of nitric oxide on the haemodynamic and blood gas parameters were investigated. The inhalation of 40 and 80 ppm of nitric oxide during: serotonin-induced pulmonary hypertension in calves resulted in a significant fall of the mean pulmonary artery pressure. The inhalation of nitric oxide also induced an amelioration of intrapulmonary oxygen transport. The intravenous administration of serotonin in calves resulted in severe systemic hypotension. Hence, the influence of the inhalation of nitric oxide on the systemic arterial pressure could not be evaluated.},
  author       = {Sustronck, Bart and van Loon, Gunther and Gasthuys, Frank and FOUBERT, L and Deprez, Piet and Muylle, Etienne},
  issn         = {0931-184X},
  journal      = {JOURNAL OF VETERINARY MEDICINE SERIES A-ZENTRALBLATT FUR VETERINARMEDIZIN REIHE A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE},
  language     = {eng},
  number       = {9},
  pages        = {513--520},
  title        = {Effect of the inhalation of nitric oxide on 5-hydroxytryptamine-induced pulmonary hypertension in calves},
  volume       = {43},
  year         = {1996},
}