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Flexible PCL tube scaffolds by winding of micro-extruded filaments

Kim Ragaert UGent, Ludwig Cardon UGent and Joris Degrieck UGent (2012) Innovative developments in virtual and physical prototyping. p.99-103
abstract
An important requirement for tissue engineering scaffolds is matching of the functional me-chanical properties to their natural tissue counterpart. Specifically for arteries this comprises the elastic re-sponse of the vessel wall to blood pressure. Human aorta has a low elastic modulus when compared to some FDA-approved synthetic polymer materials frequently used in tissue engineering. The current research en-deavours to expand the existing production technology of 3D plotting to winding of micro-extruded filaments in order to obtain flexible polymer tubes with continuous fibre. Tube scaffolds are manufactured by conven-tional 3D plotting and by winding. Their structure and quasi-static mechanical properties are evaluated and compared to human aorta. Winded tubes are found to be far more suitable for application as a blood vessel scaffold than their 3D plotted counterparts.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
keyword
FABRICATION, DESIGN, IN-VITRO, VASCULAR GRAFTS, ABDOMINAL AORTAS, MECHANICAL-PROPERTIES, TISSUE ENGINEERING SCAFFOLDS, BLOOD-VESSEL
in
Innovative developments in virtual and physical prototyping
editor
PJ Bartolo, ACS DeLemos, APO Tojeira, AMH Pereira, AJ Mateus, ALA Mendes, C DosSantos, DMF Freitas, HM Bartolo, HD Almeida, IM DosReis, JR Dias, MAN Domingos, NMF Alves, RFB Pereira, TMF Patricio and Telma Margarida Dias Ferreira
pages
99 - 103
publisher
CRC Press
place of publication
Boca Raton, FL, USA
conference name
5th International conference on Advanced Research in Virtual and Rapid Prototyping (VRAP 2011)
conference location
Leiria , Portugal
conference start
2011-09-28
conference end
2011-10-01
Web of Science type
Proceedings Paper
Web of Science id
000305445600015
ISBN
9780415684187
9780203181416
DOI
10.1201/b11341-18
language
English
UGent publication?
yes
classification
P1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1906395
handle
http://hdl.handle.net/1854/LU-1906395
alternative location
http://www.crcnetbase.com/isbn/9780415684187
date created
2011-09-22 11:02:25
date last changed
2013-07-19 09:50:31
@inproceedings{1906395,
  abstract     = {An important requirement for tissue engineering scaffolds is matching of the functional me-chanical properties to their natural tissue counterpart. Specifically for arteries this comprises the elastic re-sponse of the vessel wall to blood pressure. Human aorta has a low elastic modulus when compared to some FDA-approved synthetic polymer materials frequently used in tissue engineering. The current research en-deavours to expand the existing production technology of 3D plotting to winding of micro-extruded filaments in order to obtain flexible polymer tubes with continuous fibre. Tube scaffolds are manufactured by conven-tional 3D plotting and by winding. Their structure and quasi-static mechanical properties are evaluated and compared to human aorta. Winded tubes are found to be far more suitable for application as a blood vessel scaffold than their 3D plotted counterparts.},
  author       = {Ragaert, Kim and Cardon, Ludwig and Degrieck, Joris},
  booktitle    = {Innovative developments in virtual and physical prototyping},
  editor       = {Bartolo, PJ and DeLemos, ACS and Tojeira, APO and Pereira, AMH and Mateus, AJ and Mendes, ALA and DosSantos, C and Freitas, DMF and Bartolo, HM and Almeida, HD and DosReis, IM and Dias, JR and Domingos, MAN and Alves, NMF and Pereira, RFB and Patricio, TMF and Dias Ferreira, Telma Margarida},
  isbn         = {9780415684187},
  keyword      = {FABRICATION,DESIGN,IN-VITRO,VASCULAR GRAFTS,ABDOMINAL AORTAS,MECHANICAL-PROPERTIES,TISSUE ENGINEERING SCAFFOLDS,BLOOD-VESSEL},
  language     = {eng},
  location     = {Leiria , Portugal},
  pages        = {99--103},
  publisher    = {CRC Press},
  title        = {Flexible PCL tube scaffolds by winding of micro-extruded filaments},
  url          = {http://dx.doi.org/10.1201/b11341-18},
  year         = {2012},
}

Chicago
Ragaert, Kim, Ludwig Cardon, and Joris Degrieck. 2012. “Flexible PCL Tube Scaffolds by Winding of Micro-extruded Filaments.” In Innovative Developments in Virtual and Physical Prototyping, ed. PJ Bartolo, ACS DeLemos, APO Tojeira, AMH Pereira, AJ Mateus, ALA Mendes, C DosSantos, et al., 99–103. Boca Raton, FL, USA: CRC Press.
APA
Ragaert, K., Cardon, L., & Degrieck, J. (2012). Flexible PCL tube scaffolds by winding of micro-extruded filaments. In PJ Bartolo, A. DeLemos, A. Tojeira, A. Pereira, A. Mateus, A. Mendes, C. DosSantos, et al. (Eds.), Innovative developments in virtual and physical prototyping (pp. 99–103). Presented at the 5th International conference on Advanced Research in Virtual and Rapid Prototyping (VRAP 2011), Boca Raton, FL, USA: CRC Press.
Vancouver
1.
Ragaert K, Cardon L, Degrieck J. Flexible PCL tube scaffolds by winding of micro-extruded filaments. In: Bartolo P, DeLemos A, Tojeira A, Pereira A, Mateus A, Mendes A, et al., editors. Innovative developments in virtual and physical prototyping. Boca Raton, FL, USA: CRC Press; 2012. p. 99–103.
MLA
Ragaert, Kim, Ludwig Cardon, and Joris Degrieck. “Flexible PCL Tube Scaffolds by Winding of Micro-extruded Filaments.” Innovative Developments in Virtual and Physical Prototyping. Ed. PJ Bartolo et al. Boca Raton, FL, USA: CRC Press, 2012. 99–103. Print.