Survival analysis and clinical medicine: an observational comparison of the implantable cardioverter defibrillator, amiodarone treatment, and heart transplantation
- Author
- H Ector, Luc Jordaens and J Vanhaecke
- Organization
- Abstract
- In clinical practice, observational studies remain necessary for evaluating accepted and new treatments. The comparison of results remains difficult and often controversial, because of a wide variation in clinical characteristics. Survival analysis and calculation of the standardized mortality ratio offer the possibility to compare outcomes in different study groups. We have applied these techniques to an observational comparison of outcomes in three groups of patients, followed in two university centres: (i) patients treated with an implantable cardioverter defibrillator; (ii) patients under amiodarone treatment and (iii) recipients of a heart transplant. There was no statistically significant difference in the cumulative survival from total mortality. The standardized mortality ratio revealed the different natural history of patients undergoing heart transplantation.
- Keywords
- TRIALS, DEATH, AVID DISSENT, ADDITIONAL BASIC SCIENCE, heart transplantation, amiodarone, implantable cardioverter defibrillator, standardized mortality ratio, total mortality, trials
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-189964
- MLA
- Ector, H., et al. “Survival Analysis and Clinical Medicine: An Observational Comparison of the Implantable Cardioverter Defibrillator, Amiodarone Treatment, and Heart Transplantation.” EUROPEAN HEART JOURNAL, vol. 17, no. 9, 1996, pp. 1444–47.
- APA
- Ector, H., Jordaens, L., & Vanhaecke, J. (1996). Survival analysis and clinical medicine: an observational comparison of the implantable cardioverter defibrillator, amiodarone treatment, and heart transplantation. EUROPEAN HEART JOURNAL, 17(9), 1444–1447.
- Chicago author-date
- Ector, H, Luc Jordaens, and J Vanhaecke. 1996. “Survival Analysis and Clinical Medicine: An Observational Comparison of the Implantable Cardioverter Defibrillator, Amiodarone Treatment, and Heart Transplantation.” EUROPEAN HEART JOURNAL 17 (9): 1444–47.
- Chicago author-date (all authors)
- Ector, H, Luc Jordaens, and J Vanhaecke. 1996. “Survival Analysis and Clinical Medicine: An Observational Comparison of the Implantable Cardioverter Defibrillator, Amiodarone Treatment, and Heart Transplantation.” EUROPEAN HEART JOURNAL 17 (9): 1444–1447.
- Vancouver
- 1.Ector H, Jordaens L, Vanhaecke J. Survival analysis and clinical medicine: an observational comparison of the implantable cardioverter defibrillator, amiodarone treatment, and heart transplantation. EUROPEAN HEART JOURNAL. 1996;17(9):1444–7.
- IEEE
- [1]H. Ector, L. Jordaens, and J. Vanhaecke, “Survival analysis and clinical medicine: an observational comparison of the implantable cardioverter defibrillator, amiodarone treatment, and heart transplantation,” EUROPEAN HEART JOURNAL, vol. 17, no. 9, pp. 1444–1447, 1996.
@article{189964,
abstract = {{In clinical practice, observational studies remain necessary for evaluating accepted and new treatments. The comparison of results remains difficult and often controversial, because of a wide variation in clinical characteristics. Survival analysis and calculation of the standardized mortality ratio offer the possibility to compare outcomes in different study groups. We have applied these techniques to an observational comparison of outcomes in three groups of patients, followed in two university centres: (i) patients treated with an implantable cardioverter defibrillator; (ii) patients under amiodarone treatment and (iii) recipients of a heart transplant. There was no statistically significant difference in the cumulative survival from total mortality. The standardized mortality ratio revealed the different natural history of patients undergoing heart transplantation.}},
author = {{Ector, H and Jordaens, Luc and Vanhaecke, J}},
issn = {{0195-668X}},
journal = {{EUROPEAN HEART JOURNAL}},
keywords = {{TRIALS,DEATH,AVID DISSENT,ADDITIONAL BASIC SCIENCE,heart transplantation,amiodarone,implantable cardioverter defibrillator,standardized mortality ratio,total mortality,trials}},
language = {{eng}},
number = {{9}},
pages = {{1444--1447}},
title = {{Survival analysis and clinical medicine: an observational comparison of the implantable cardioverter defibrillator, amiodarone treatment, and heart transplantation}},
volume = {{17}},
year = {{1996}},
}