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Toward clinical proteomics on a next-generation sequencing platform

(2011) ANALYTICAL CHEMISTRY. 83(3). p.666-670
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Abstract
We report the first next generation sequencing (NGS) application to identify and quantify proteins. Customization of protein specific aptamers enabled direct conversion of serum protein information into NGS read outs. The intrinsic ability of aptamer sequencing to highly multiplex protein detection and quantification, together with the prospect of DNA sequencing further evolving into a commodity technology, could constitute the core of a novel, universal diagnostics paradigm.
Keywords
GENOME, MOLECULES, SELECTION, LIGANDS, RNA-SEQ, NON-SELEX, DNA APTAMERS, SMART APTAMERS, AMPLIFICATION-FREE, CAPILLARY-ELECTROPHORESIS

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Chicago
Turner, Daniel J, Robin Tuytten, Kris PF Janssen, Jeroen Lammertyn, Jan Wuyts, Jeroen Pollet, Sven Eyckerman, Clive Brown, and Koen Kas. 2011. “Toward Clinical Proteomics on a Next-generation Sequencing Platform.” Analytical Chemistry 83 (3): 666–670.
APA
Turner, D. J., Tuytten, R., Janssen, K. P., Lammertyn, J., Wuyts, J., Pollet, J., Eyckerman, S., et al. (2011). Toward clinical proteomics on a next-generation sequencing platform. ANALYTICAL CHEMISTRY, 83(3), 666–670.
Vancouver
1.
Turner DJ, Tuytten R, Janssen KP, Lammertyn J, Wuyts J, Pollet J, et al. Toward clinical proteomics on a next-generation sequencing platform. ANALYTICAL CHEMISTRY. 2011;83(3):666–70.
MLA
Turner, Daniel J, Robin Tuytten, Kris PF Janssen, et al. “Toward Clinical Proteomics on a Next-generation Sequencing Platform.” ANALYTICAL CHEMISTRY 83.3 (2011): 666–670. Print.
@article{1891054,
  abstract     = {We report the first next generation sequencing (NGS) application to identify and quantify proteins. Customization of protein specific aptamers enabled direct conversion of serum protein information into NGS read outs. The intrinsic ability of aptamer sequencing to highly multiplex protein detection and quantification, together with the prospect of DNA sequencing further evolving into a commodity technology, could constitute the core of a novel, universal diagnostics paradigm.},
  author       = {Turner, Daniel J and Tuytten, Robin and Janssen, Kris PF and Lammertyn, Jeroen and Wuyts, Jan and Pollet, Jeroen and Eyckerman, Sven and Brown, Clive and Kas, Koen},
  issn         = {0003-2700},
  journal      = {ANALYTICAL CHEMISTRY},
  keyword      = {GENOME,MOLECULES,SELECTION,LIGANDS,RNA-SEQ,NON-SELEX,DNA APTAMERS,SMART APTAMERS,AMPLIFICATION-FREE,CAPILLARY-ELECTROPHORESIS},
  language     = {eng},
  number       = {3},
  pages        = {666--670},
  title        = {Toward clinical proteomics on a next-generation sequencing platform},
  url          = {http://dx.doi.org/10.1021/ac102666n},
  volume       = {83},
  year         = {2011},
}

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