Combining quantitative proteomics data processing workflows for greater sensitivity
- Author
- Niklaas Colaert (UGent) , Christophe Van Huele (UGent) , Sven Degroeve (UGent) , An Staes (UGent) , Joël Vandekerckhove (UGent) , Kris Gevaert (UGent) and Lennart Martens (UGent)
- Organization
- Project
- Abstract
- We here describe a normalization method to combine quantitative proteomics data. By merging the output of two popular quantification software packages, we obtained a 20% increase (on average) in the number of quantified human proteins without suffering from a loss of quality. Our integrative workflow is freely available through our user-friendly, open-source Rover software (http://compomics-rover.googlecode.com/).
- Keywords
- RATES, TOOL, IMPROVING SENSITIVITY, PROTEIN QUANTIFICATION, IMPROVING SENSITIVITY, PROTEIN QUANTIFICATION, PEPTIDE IDENTIFICATION, RATES, MULTIPLE SEARCH ENGINES, MASS-SPECTROMETRY, TOOL
Downloads
-
(...).pdf
- full text
- |
- UGent only
- |
- |
- 472.44 KB
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-1887669
- MLA
- Colaert, Niklaas, et al. “Combining Quantitative Proteomics Data Processing Workflows for Greater Sensitivity.” NATURE METHODS, vol. 8, no. 6, 2011, pp. 481-U66, doi:10.1038/NMETH.1604.
- APA
- Colaert, N., Van Huele, C., Degroeve, S., Staes, A., Vandekerckhove, J., Gevaert, K., & Martens, L. (2011). Combining quantitative proteomics data processing workflows for greater sensitivity. NATURE METHODS, 8(6), 481-U66. https://doi.org/10.1038/NMETH.1604
- Chicago author-date
- Colaert, Niklaas, Christophe Van Huele, Sven Degroeve, An Staes, Joël Vandekerckhove, Kris Gevaert, and Lennart Martens. 2011. “Combining Quantitative Proteomics Data Processing Workflows for Greater Sensitivity.” NATURE METHODS 8 (6): 481-U66. https://doi.org/10.1038/NMETH.1604.
- Chicago author-date (all authors)
- Colaert, Niklaas, Christophe Van Huele, Sven Degroeve, An Staes, Joël Vandekerckhove, Kris Gevaert, and Lennart Martens. 2011. “Combining Quantitative Proteomics Data Processing Workflows for Greater Sensitivity.” NATURE METHODS 8 (6): 481-U66. doi:10.1038/NMETH.1604.
- Vancouver
- 1.Colaert N, Van Huele C, Degroeve S, Staes A, Vandekerckhove J, Gevaert K, et al. Combining quantitative proteomics data processing workflows for greater sensitivity. NATURE METHODS. 2011;8(6):481-U66.
- IEEE
- [1]N. Colaert et al., “Combining quantitative proteomics data processing workflows for greater sensitivity,” NATURE METHODS, vol. 8, no. 6, pp. 481-U66, 2011.
@article{1887669,
abstract = {{We here describe a normalization method to combine quantitative proteomics data. By merging the output of two popular quantification software packages, we obtained a 20% increase (on average) in the number of quantified human proteins without suffering from a loss of quality. Our integrative workflow is freely available through our user-friendly, open-source Rover software (http://compomics-rover.googlecode.com/).}},
author = {{Colaert, Niklaas and Van Huele, Christophe and Degroeve, Sven and Staes, An and Vandekerckhove, Joël and Gevaert, Kris and Martens, Lennart}},
issn = {{1548-7091}},
journal = {{NATURE METHODS}},
keywords = {{RATES,TOOL,IMPROVING SENSITIVITY,PROTEIN QUANTIFICATION,IMPROVING SENSITIVITY,PROTEIN QUANTIFICATION,PEPTIDE IDENTIFICATION,RATES,MULTIPLE SEARCH ENGINES,MASS-SPECTROMETRY,TOOL}},
language = {{eng}},
number = {{6}},
pages = {{481--U66}},
title = {{Combining quantitative proteomics data processing workflows for greater sensitivity}},
url = {{http://doi.org/10.1038/NMETH.1604}},
volume = {{8}},
year = {{2011}},
}
- Altmetric
- View in Altmetric
- Web of Science
- Times cited: