Initial experience with the use of preoperative transarterial chemoembolization in the treatment of liver metastasis
- Author
- Wim Ceelen (UGent) , Marleen Praet, Geert Villeirs (UGent) , Luc Defreyne (UGent) , Piet Pattyn (UGent) , Uwe Hesse (UGent) and Bernard de Hemptinne (UGent)
- Organization
- Abstract
- We retrospectively evaluated the influence of preoperative Transarterial Chemoembolizaticn (TAE) on technique and complications, tumour histology, and disease-free survival after surgery for hepatic metastasis. In a 2-year period, a total of 23 patients were treated. In a first group of 14 patients, preoperative TAE was performed; in a second group of 9 patients only surgical resection was done. Extensive tumour necrosis was seen in the majority of patients treated with TAE; in tumours with an important fibrotic component, embolization was less effective. No significant effect was seen on operating time, transfusion requirement or perioperative complication rate. In the group of patients who underwent TAE, survival rate was 93% after a mean follow-up period of 15,5 months (SD: 12,5); recurrence was seen in only 8% of the survivors. In the second group, however, mortality was 33% after a median follow-up of 17,5 months (SD : 10), and recurrence was present in 66,7% of the survivors. These results indicate that preoperative TAE reduces the recurrence rate in the first postoperative year. Thereby survival may be improved in patients with resectable metastatic liver cancer.
- Keywords
- liver neoplasms, neoplasms metastasis, chemoembolization, therapeutic, hepatectomy, COLORECTAL-CARCINOMA, HEPATOCELLULAR-CARCINOMA, HEPATIC METASTASES, RESECTION
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-187278
- MLA
- Ceelen, Wim, et al. “Initial Experience with the Use of Preoperative Transarterial Chemoembolization in the Treatment of Liver Metastasis.” ACTA CHIRURGICA BELGICA, vol. 96, no. 1, 1996, pp. 37–40.
- APA
- Ceelen, W., Praet, M., Villeirs, G., Defreyne, L., Pattyn, P., Hesse, U., & de Hemptinne, B. (1996). Initial experience with the use of preoperative transarterial chemoembolization in the treatment of liver metastasis. ACTA CHIRURGICA BELGICA, 96(1), 37–40.
- Chicago author-date
- Ceelen, Wim, Marleen Praet, Geert Villeirs, Luc Defreyne, Piet Pattyn, Uwe Hesse, and Bernard de Hemptinne. 1996. “Initial Experience with the Use of Preoperative Transarterial Chemoembolization in the Treatment of Liver Metastasis.” ACTA CHIRURGICA BELGICA 96 (1): 37–40.
- Chicago author-date (all authors)
- Ceelen, Wim, Marleen Praet, Geert Villeirs, Luc Defreyne, Piet Pattyn, Uwe Hesse, and Bernard de Hemptinne. 1996. “Initial Experience with the Use of Preoperative Transarterial Chemoembolization in the Treatment of Liver Metastasis.” ACTA CHIRURGICA BELGICA 96 (1): 37–40.
- Vancouver
- 1.Ceelen W, Praet M, Villeirs G, Defreyne L, Pattyn P, Hesse U, et al. Initial experience with the use of preoperative transarterial chemoembolization in the treatment of liver metastasis. ACTA CHIRURGICA BELGICA. 1996;96(1):37–40.
- IEEE
- [1]W. Ceelen et al., “Initial experience with the use of preoperative transarterial chemoembolization in the treatment of liver metastasis,” ACTA CHIRURGICA BELGICA, vol. 96, no. 1, pp. 37–40, 1996.
@article{187278,
abstract = {{We retrospectively evaluated the influence of preoperative Transarterial Chemoembolizaticn (TAE) on technique and complications, tumour histology, and disease-free survival after surgery for hepatic metastasis. In a 2-year period, a total of 23 patients were treated. In a first group of 14 patients, preoperative TAE was performed; in a second group of 9 patients only surgical resection was done.
Extensive tumour necrosis was seen in the majority of patients treated with TAE; in tumours with an important fibrotic component, embolization was less effective. No significant effect was seen on operating time, transfusion requirement or perioperative complication rate. In the group of patients who underwent TAE, survival rate was 93% after a mean follow-up period of 15,5 months (SD: 12,5); recurrence was seen in only 8% of the survivors. In the second group, however, mortality was 33% after a median follow-up of 17,5 months (SD : 10), and recurrence was present in 66,7% of the survivors.
These results indicate that preoperative TAE reduces the recurrence rate in the first postoperative year. Thereby survival may be improved in patients with resectable metastatic liver cancer.}},
author = {{Ceelen, Wim and Praet, Marleen and Villeirs, Geert and Defreyne, Luc and Pattyn, Piet and Hesse, Uwe and de Hemptinne, Bernard}},
issn = {{0001-5458}},
journal = {{ACTA CHIRURGICA BELGICA}},
keywords = {{liver neoplasms,neoplasms metastasis,chemoembolization,therapeutic,hepatectomy,COLORECTAL-CARCINOMA,HEPATOCELLULAR-CARCINOMA,HEPATIC METASTASES,RESECTION}},
language = {{eng}},
number = {{1}},
pages = {{37--40}},
title = {{Initial experience with the use of preoperative transarterial chemoembolization in the treatment of liver metastasis}},
volume = {{96}},
year = {{1996}},
}