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Cystitis: symptomatology in women with suspected uncomplicated urinary tract infection

Stefan Heytens UGent, An De Sutter UGent, David De Backer UGent, Gerda Verschraegen and Thierry Christiaens UGent (2011) JOURNAL OF WOMENS HEALTH. 20(7). p.1117-1121
abstract
Background: Although cystitis in women is very common in general practice, its evolution in symptoms has not been clearly studied. Qualitative research has pointed to other than the classic symptomatology. Methods: This was a prospective observational study of the symptomatology at presentation and the evolution of the symptoms in treated women with suspected uncomplicated urinary tract infection (UTI). Women consulting their general practitioner (GP) for dysuria, urgency, or frequency produced a urine sample (for bacteriologic processing) and kept a diary until the end of the symptoms. Exclusion criteria included complaints >1 week, fever, vaginal discharge, and known pathology. Results: Of the 300 asked to participate, 148 (49%) returned the diary. Although none of the patients developed acute pyelonephritis, a substantial number of the women had such complaints as feeling feverish (33% in culture-positive group, 38% in culture-negative group), back pains (44% vs. 56%), and feeling weak and tired (71% vs. 65%). Differences between the culture-positive and culture-negative groups were not statistically significant except for the duration of symptoms, which was shorter in the culture-positive group (4 vs. 6 days). More severe symptoms at inclusion were correlated with a longer duration of these symptoms. Conclusions: The spectrum of complaints in women with suspected uncomplicated UTI is broad and comprises a number of symptoms usually associated with an upper UTI. The occurrence of these symptoms should not automatically prompt GPs to prescribe broad-spectrum antibiotics. Moreover, the duration of symptoms exceeding the recommended duration of antibiotic therapy does not indicate therapy failure and, thus, the need for changing antibiotic therapy.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
PLACEBO, NATURAL COURSE
journal title
JOURNAL OF WOMENS HEALTH
J. Womens Health
volume
20
issue
7
pages
1117 - 1121
Web of Science type
Article
Web of Science id
000292541100016
JCR category
WOMEN'S STUDIES
JCR impact factor
1.569 (2011)
JCR rank
4/38 (2011)
JCR quartile
1 (2011)
ISSN
1540-9996
DOI
10.1089/jwh.2010.2302
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1861665
handle
http://hdl.handle.net/1854/LU-1861665
date created
2011-07-27 11:23:35
date last changed
2016-12-19 15:46:25
@article{1861665,
  abstract     = {Background: Although cystitis in women is very common in general practice, its evolution in symptoms has not been clearly studied. Qualitative research has pointed to other than the classic symptomatology. Methods: This was a prospective observational study of the symptomatology at presentation and the evolution of the symptoms in treated women with suspected uncomplicated urinary tract infection (UTI). Women consulting their general practitioner (GP) for dysuria, urgency, or frequency produced a urine sample (for bacteriologic processing) and kept a diary until the end of the symptoms. Exclusion criteria included complaints {\textrangle}1 week, fever, vaginal discharge, and known pathology. Results: Of the 300 asked to participate, 148 (49\%) returned the diary. Although none of the patients developed acute pyelonephritis, a substantial number of the women had such complaints as feeling feverish (33\% in culture-positive group, 38\% in culture-negative group), back pains (44\% vs. 56\%), and feeling weak and tired (71\% vs. 65\%). Differences between the culture-positive and culture-negative groups were not statistically significant except for the duration of symptoms, which was shorter in the culture-positive group (4 vs. 6 days). More severe symptoms at inclusion were correlated with a longer duration of these symptoms. Conclusions: The spectrum of complaints in women with suspected uncomplicated UTI is broad and comprises a number of symptoms usually associated with an upper UTI. The occurrence of these symptoms should not automatically prompt GPs to prescribe broad-spectrum antibiotics. Moreover, the duration of symptoms exceeding the recommended duration of antibiotic therapy does not indicate therapy failure and, thus, the need for changing antibiotic therapy.},
  author       = {Heytens, Stefan and De Sutter, An and De Backer, David and Verschraegen, Gerda and Christiaens, Thierry},
  issn         = {1540-9996},
  journal      = {JOURNAL OF WOMENS HEALTH},
  keyword      = {PLACEBO,NATURAL COURSE},
  language     = {eng},
  number       = {7},
  pages        = {1117--1121},
  title        = {Cystitis: symptomatology in women with suspected uncomplicated urinary tract infection},
  url          = {http://dx.doi.org/10.1089/jwh.2010.2302},
  volume       = {20},
  year         = {2011},
}

Chicago
Heytens, Stefan, An De Sutter, David De Backer, Gerda Verschraegen, and Thierry Christiaens. 2011. “Cystitis: Symptomatology in Women with Suspected Uncomplicated Urinary Tract Infection.” Journal of Womens Health 20 (7): 1117–1121.
APA
Heytens, S., De Sutter, A., De Backer, D., Verschraegen, G., & Christiaens, T. (2011). Cystitis: symptomatology in women with suspected uncomplicated urinary tract infection. JOURNAL OF WOMENS HEALTH, 20(7), 1117–1121.
Vancouver
1.
Heytens S, De Sutter A, De Backer D, Verschraegen G, Christiaens T. Cystitis: symptomatology in women with suspected uncomplicated urinary tract infection. JOURNAL OF WOMENS HEALTH. 2011;20(7):1117–21.
MLA
Heytens, Stefan, An De Sutter, David De Backer, et al. “Cystitis: Symptomatology in Women with Suspected Uncomplicated Urinary Tract Infection.” JOURNAL OF WOMENS HEALTH 20.7 (2011): 1117–1121. Print.