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Applications of mass spectrometry in the trace element analysis of biological materials

Luc Moens (UGent)
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Abstract
The importance of mass spectrometry for the analysis of biological material is illustrated by reviewing the different mass spectrometric methods applied and describing some typical applications published recently. Though atomic absorption spectrometry is used in the majority of analyses of biological material, most mass spectrometric methods have been used to some extent for trace element determination in biomedical research. The relative importance of the different methods is estimated by reviewing recent research papers. It is striking that especially inductively coupled plasma mass spectrometry is increasingly being applied, partly because the method can be used on-line after chromatographic separation, in speciation studies. Mass spectrometric methods prove to offer unique possibilities in stable isotope tracer studies and for this purpose also experimentally demanding methods such as thermal ionization mass spectrometry and accelerator mass spectrometry are frequently used.
Keywords
PERFORMANCE LIQUID-CHROMATOGRAPHY, INDUCTIVELY-COUPLED PLASMA, CAPILLARY ELECTROPHORESIS, SPECTRAL INTERFERENCES, THERMAL IONIZATION, ISOTOPE RATIOS, HUMAN-SERUM, ION-SOURCE, ICP-MS, URINE

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Citation

Please use this url to cite or link to this publication:

Chicago
Moens, Luc. 1997. “Applications of Mass Spectrometry in the Trace Element Analysis of Biological Materials.” Fresenius Journal of Analytical Chemistry 359 (4-5): 309–316.
APA
Moens, L. (1997). Applications of mass spectrometry in the trace element analysis of biological materials. FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 359(4-5), 309–316. Presented at the 3rd Symposium on Mass Spectrometric Method of Elemental Trace Analysis ; 12th ICP-MS Users Meeting.
Vancouver
1.
Moens L. Applications of mass spectrometry in the trace element analysis of biological materials. FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY. 1997;359(4-5):309–16.
MLA
Moens, Luc. “Applications of Mass Spectrometry in the Trace Element Analysis of Biological Materials.” FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY 359.4-5 (1997): 309–316. Print.
@article{185586,
  abstract     = {The importance of mass spectrometry for the analysis of biological material is illustrated by reviewing the different mass spectrometric methods applied and describing some typical applications published recently. Though atomic absorption spectrometry is used in the majority of analyses of biological material, most mass spectrometric methods have been used to some extent for trace element determination in biomedical research. The relative importance of the different methods is estimated by reviewing recent research papers. It is striking that especially inductively coupled plasma mass spectrometry is increasingly being applied, partly because the method can be used on-line after chromatographic separation, in speciation studies. Mass spectrometric methods prove to offer unique possibilities in stable isotope tracer studies and for this purpose also experimentally demanding methods such as thermal ionization mass spectrometry and accelerator mass spectrometry are frequently used.},
  author       = {Moens, Luc},
  issn         = {0937-0633},
  journal      = {FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY},
  keyword      = {PERFORMANCE LIQUID-CHROMATOGRAPHY,INDUCTIVELY-COUPLED PLASMA,CAPILLARY ELECTROPHORESIS,SPECTRAL INTERFERENCES,THERMAL IONIZATION,ISOTOPE RATIOS,HUMAN-SERUM,ION-SOURCE,ICP-MS,URINE},
  language     = {eng},
  location     = {Julich, Germany},
  number       = {4-5},
  pages        = {309--316},
  title        = {Applications of mass spectrometry in the trace element analysis of biological materials},
  url          = {http://dx.doi.org/10.1007/s002160050579},
  volume       = {359},
  year         = {1997},
}

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