Sizing nanomatter in biological fluids by fluorescence single particle tracking
(2010) NANO LETTERS. 10(11). p.4435-4442- abstract
- Accurate sizing of nanoparticles in biological media is important for drug delivery and biomedical imaging applications since size directly influences the nanoparticle processing and nanotoxicity in vivo. Using fluorescence single particle cracking we have succeeded for the first time in following the aggregation of drug delivery nanoparticles in real time in undiluted whole blood. We demonstrate that, by using a suitable surface functionalization, nanoparticle aggregation in the blood circulation is prevented to a large extent.
Please use this url to cite or link to this publication:
http://hdl.handle.net/1854/LU-1850220
- author
- Kevin Braeckmans UGent, Kevin Buyens UGent, Wim Bouquet-Geerardyn UGent, Chris Vervaet UGent, Philippe Joye UGent, Filip De Vos UGent, Laurent Plawinski, Loic Doeuvre, Eduardo Angles-Cano, Niek Sanders UGent, Jo Demeester UGent and Stefaan De Smedt UGent
- organization
- year
- 2010
- type
- journalArticle (original)
- publication status
- published
- subject
- keyword
- MICROPARTICLES, DYNAMICS, LIPOSOMES, DELIVERY, POLY(ETHYLENE GLYCOL), CELLS, DRUG, SIZE, Nanobiophotonics, nanoparticles, drug delivery, nanomedicines, medical diagnostics
- journal title
- NANO LETTERS
- Nano Lett.
- volume
- 10
- issue
- 11
- pages
- 4435 - 4442
- Web of Science type
- Article
- Web of Science id
- 000283907600024
- JCR category
- MATERIALS SCIENCE, MULTIDISCIPLINARY
- JCR impact factor
- 12.186 (2010)
- JCR rank
- 5/219 (2010)
- JCR quartile
- 1 (2010)
- ISSN
- 1530-6984
- DOI
- 10.1021/nl103264u
- language
- English
- UGent publication?
- yes
- classification
- A1
- copyright statement
- I have transferred the copyright for this publication to the publisher
- id
- 1850220
- handle
- http://hdl.handle.net/1854/LU-1850220
- date created
- 2011-06-30 16:56:27
- date last changed
- 2011-07-05 13:21:55
@article{1850220,
abstract = {Accurate sizing of nanoparticles in biological media is important for drug delivery and biomedical imaging applications since size directly influences the nanoparticle processing and nanotoxicity in vivo. Using fluorescence single particle cracking we have succeeded for the first time in following the aggregation of drug delivery nanoparticles in real time in undiluted whole blood. We demonstrate that, by using a suitable surface functionalization, nanoparticle aggregation in the blood circulation is prevented to a large extent.},
author = {Braeckmans, Kevin and Buyens, Kevin and Bouquet-Geerardyn, Wim and Vervaet, Chris and Joye, Philippe and De Vos, Filip and Plawinski, Laurent and Doeuvre, Loic and Angles-Cano, Eduardo and Sanders, Niek and Demeester, Jo and De Smedt, Stefaan},
issn = {1530-6984},
journal = {NANO LETTERS},
keyword = {MICROPARTICLES,DYNAMICS,LIPOSOMES,DELIVERY,POLY(ETHYLENE GLYCOL),CELLS,DRUG,SIZE,Nanobiophotonics,nanoparticles,drug delivery,nanomedicines,medical diagnostics},
language = {eng},
number = {11},
pages = {4435--4442},
title = {Sizing nanomatter in biological fluids by fluorescence single particle tracking},
url = {http://dx.doi.org/10.1021/nl103264u},
volume = {10},
year = {2010},
}
- Chicago
- Braeckmans, Kevin, Kevin Buyens, Wim Bouquet-Geerardyn, Chris Vervaet, Philippe Joye, Filip De Vos, Laurent Plawinski, et al. 2010. “Sizing Nanomatter in Biological Fluids by Fluorescence Single Particle Tracking.” Nano Letters 10 (11): 4435–4442.
- APA
- Braeckmans, K., Buyens, K., Bouquet-Geerardyn, W., Vervaet, C., Joye, P., De Vos, F., Plawinski, L., et al. (2010). Sizing nanomatter in biological fluids by fluorescence single particle tracking. NANO LETTERS, 10(11), 4435–4442.
- Vancouver
- 1.Braeckmans K, Buyens K, Bouquet-Geerardyn W, Vervaet C, Joye P, De Vos F, et al. Sizing nanomatter in biological fluids by fluorescence single particle tracking. NANO LETTERS. 2010;10(11):4435–42.
- MLA
- Braeckmans, Kevin, Kevin Buyens, Wim Bouquet-Geerardyn, et al. “Sizing Nanomatter in Biological Fluids by Fluorescence Single Particle Tracking.” NANO LETTERS 10.11 (2010): 4435–4442. Print.