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Aspiration pneumonia : an underestimated cause of severe respiratory failure in patients with haematological malignancies and severe oral mucositis?

(2010) ACTA CLINICA BELGICA. 65(6). p.416-419
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Abstract
Aspiration pneumonia is rarely considered in the differential diagnosis of respiratory failure in patients suffering from haematologic malignancies in daily practice. We describe four patients who were admitted with severe respiratory failure in the ICU over a one-year-period prospective survey (a total of 72 patients with haematological malignancies of which 34 presented with respiratory failure). All of these patients had chemotherapy-induced severe oral mucositis (WHO grade III-IV) for which three of them received opioids. All had a history of cough after oral rinsing and two of them experienced sudden brief desaturation in the days before ICU referral. Two of these patients, both in allogeneic bone marrow transplant setting, died. With this data, we want to draw the attention to the diagnosis of aspiration pneumonia in this group of patients.
Keywords
INTENSIVE-CARE-UNIT, NECK-CANCER, Respiratory insufficiency, HEAD, CHEMORADIATION, PREVENTION, oral rinses, mouth washes, oral mucositis, aspiration pneumonia, VENTILATOR-ASSOCIATED PNEUMONIA

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Chicago
De Neve, Nicolaas, Dominique Benoit, Pieter Depuydt, Fritz Offner, JOKE NOLLET, Lucien Noens, and Johan Decruyenaere. 2010. “Aspiration Pneumonia : an Underestimated Cause of Severe Respiratory Failure in Patients with Haematological Malignancies and Severe Oral Mucositis?” Acta Clinica Belgica 65 (6): 416–419.
APA
De Neve, Nicolaas, Benoit, D., Depuydt, P., Offner, F., NOLLET, J., Noens, L., & Decruyenaere, J. (2010). Aspiration pneumonia : an underestimated cause of severe respiratory failure in patients with haematological malignancies and severe oral mucositis? ACTA CLINICA BELGICA, 65(6), 416–419.
Vancouver
1.
De Neve N, Benoit D, Depuydt P, Offner F, NOLLET J, Noens L, et al. Aspiration pneumonia : an underestimated cause of severe respiratory failure in patients with haematological malignancies and severe oral mucositis? ACTA CLINICA BELGICA. 2010;65(6):416–9.
MLA
De Neve, Nicolaas, Dominique Benoit, Pieter Depuydt, et al. “Aspiration Pneumonia : an Underestimated Cause of Severe Respiratory Failure in Patients with Haematological Malignancies and Severe Oral Mucositis?” ACTA CLINICA BELGICA 65.6 (2010): 416–419. Print.
@article{1843456,
  abstract     = {Aspiration pneumonia is rarely considered in the differential diagnosis of respiratory failure in patients suffering from haematologic malignancies in daily practice. We describe four patients who were admitted with severe respiratory failure in the ICU over a one-year-period prospective survey (a total of 72 patients with haematological malignancies of which 34 presented with respiratory failure). All of these patients had chemotherapy-induced severe oral mucositis (WHO grade III-IV) for which three of them received opioids. All had a history of cough after oral rinsing and two of them experienced sudden brief desaturation in the days before ICU referral. Two of these patients, both in allogeneic bone marrow transplant setting, died. With this data, we want to draw the attention to the diagnosis of aspiration pneumonia in this group of patients.},
  author       = {De Neve, Nicolaas and Benoit, Dominique and Depuydt, Pieter and Offner, Fritz and NOLLET, JOKE and Noens, Lucien and Decruyenaere, Johan},
  issn         = {0001-5512},
  journal      = {ACTA CLINICA BELGICA},
  keyword      = {INTENSIVE-CARE-UNIT,NECK-CANCER,Respiratory insufficiency,HEAD,CHEMORADIATION,PREVENTION,oral rinses,mouth washes,oral mucositis,aspiration pneumonia,VENTILATOR-ASSOCIATED PNEUMONIA},
  language     = {eng},
  number       = {6},
  pages        = {416--419},
  title        = {Aspiration pneumonia : an underestimated cause of severe respiratory failure in patients with haematological malignancies and severe oral mucositis?},
  volume       = {65},
  year         = {2010},
}

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