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Cloning and expression analyses of AtMRP4, a novel MRP-like gene from Arabidopsis thaliana

Rocío Sánchez-Fernández, Wilson Ardiles Diaz UGent, Marc Van Montagu UGent, Dirk Inzé UGent and Mike May UGent (1998) MOLECULAR AND GENERAL GENETICS. 258(6). p.655-662
abstract
In all organisms glutathione-conjugate transporters (GS-X pumps) mediate the detoxification of a number of xenobiotics by removing them from the cytosol. In addition, GS-X pumps appear to play a role in the processing of endogenous compounds. We have isolated a novel genomic clone from Arabidopsis thaliana that encodes a putative GS-X pump, AtMRP4, which is part of a recently defined gene family. The derived amino acid sequence shares high levels of similarity (55-63%) with human, yeast, and other Arabidopsis homologues. The expression of the different members of the AtMRP gene family in Arabidopsis cell suspensions after treatment with chemicals that modify glutathione metabolism (compounds that induce different types of stress and that act as herbicide antidotes safeners - in monocotyledonous species) revealed that the members of this gene family are differentially regulated.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
journal title
MOLECULAR AND GENERAL GENETICS
Mol. Gen. Genet.
volume
258
issue
6
pages
655 - 662
Web of Science type
Article
Web of Science id
000074805600010
ISSN
0026-8925
DOI
10.1007/s004380050779
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
178994
handle
http://hdl.handle.net/1854/LU-178994
date created
2004-01-14 13:41:00
date last changed
2013-10-28 15:56:41
@article{178994,
  abstract     = {In all organisms glutathione-conjugate transporters (GS-X pumps) mediate the detoxification of a number of xenobiotics by removing them from the cytosol. In addition, GS-X pumps appear to play a role in the processing of endogenous compounds. We have isolated a novel genomic clone from Arabidopsis thaliana that encodes a putative GS-X pump, AtMRP4, which is part of a recently defined gene family. The derived amino acid sequence shares high levels of similarity (55-63\%) with human, yeast, and other Arabidopsis homologues. The expression of the different members of the AtMRP gene family in Arabidopsis cell suspensions after treatment with chemicals that modify glutathione metabolism (compounds that induce different types of stress and that act as herbicide antidotes safeners - in monocotyledonous species) revealed that the members of this gene family are differentially regulated.},
  author       = {S{\'a}nchez-Fern{\'a}ndez, Roc{\'i}o and Ardiles Diaz, Wilson and Van Montagu, Marc and Inz{\'e}, Dirk and May, Mike},
  issn         = {0026-8925},
  journal      = {MOLECULAR AND GENERAL GENETICS},
  language     = {eng},
  number       = {6},
  pages        = {655--662},
  title        = {Cloning and expression analyses of AtMRP4, a novel MRP-like gene from Arabidopsis thaliana},
  url          = {http://dx.doi.org/10.1007/s004380050779},
  volume       = {258},
  year         = {1998},
}

Chicago
Sánchez-Fernández, Rocío, Wilson Ardiles Diaz, Marc Van Montagu, Dirk Inzé, and Mike May. 1998. “Cloning and Expression Analyses of AtMRP4, a Novel MRP-like Gene from Arabidopsis Thaliana.” Molecular and General Genetics 258 (6): 655–662.
APA
Sánchez-Fernández, R., Ardiles Diaz, W., Van Montagu, M., Inzé, D., & May, M. (1998). Cloning and expression analyses of AtMRP4, a novel MRP-like gene from Arabidopsis thaliana. MOLECULAR AND GENERAL GENETICS, 258(6), 655–662.
Vancouver
1.
Sánchez-Fernández R, Ardiles Diaz W, Van Montagu M, Inzé D, May M. Cloning and expression analyses of AtMRP4, a novel MRP-like gene from Arabidopsis thaliana. MOLECULAR AND GENERAL GENETICS. 1998;258(6):655–62.
MLA
Sánchez-Fernández, Rocío, Wilson Ardiles Diaz, Marc Van Montagu, et al. “Cloning and Expression Analyses of AtMRP4, a Novel MRP-like Gene from Arabidopsis Thaliana.” MOLECULAR AND GENERAL GENETICS 258.6 (1998): 655–662. Print.