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Age- and sex-related 99Tcm-DMSA renal uptake at 24 h in children with a normal scintigram

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Abstract
We performed a retrospective study to determine the age-and sex-related normal values of absolute Tc-99(m)-DMSA uptake at 24 h in children with normal kidneys. Of the 576 scintigrams performed between 1993 and 1996, 136 (272 kidneys) were classified as `normal' by two independent observers on the basis of the presence of a smooth cortical outline, the absence of cortical loss, relative uptake in the range 45-55% and normal echographic parenchymal findings. The 136 scintigrams were divided into eight groups based on the children's age: Group I,,<1 month (2 boys); Group II, 1-3 months (6 boys, 8 girls); Group III, 4-7 months (7 boys, 6 girls); Group IV, 8-12 months (8 boys, 8 girls); Group V, 13-24 months (14 boys, 4 girls); Group VI, 25-36 months (6 boys, 13 girls); Group VII, 37-120 months (13 boys, 19 girls); Group VIII, 121-180 months (8 boys, 10 girls). In contrast to the results of Morris et al. using absolute Tc-99(m)-DMSA uptake at 4-6 h, we found that combined left and right kidney uptake increased until age 8 months (Group I, 22.0 +/- 6.7%; Group II, 45.9 +/- 5.0%; Group III, 50.8 +/- 5.0%; Group IV, 56.9 +/- 8.5%; P=0.019), after which it reached a plateau (Group V, 55.4 +/- 7.3%; Group VI, 60.1 +/- 7.8%; Group VII, 62.0 +/- 5.0%; Group VIII, 62.4 +/- 6.3%). Uptake at 24 h tended to be lower in the girls than in the boys, but this difference was not significant.
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Chicago
Van De Wiele, Christophe, Maria Simons, Johan Vande Walle, Johan De Sutter, Karel Everaert, and Rudi Dierckx. 1998. “Age- and Sex-related 99Tcm-DMSA Renal Uptake at 24 h in Children with a Normal Scintigram.” Nuclear Medicine Communications 19 (2): 149–154.
APA
Van De Wiele, Christophe, Simons, M., Vande Walle, J., De Sutter, J., Everaert, K., & Dierckx, R. (1998). Age- and sex-related 99Tcm-DMSA renal uptake at 24 h in children with a normal scintigram. NUCLEAR MEDICINE COMMUNICATIONS, 19(2), 149–154.
Vancouver
1.
Van De Wiele C, Simons M, Vande Walle J, De Sutter J, Everaert K, Dierckx R. Age- and sex-related 99Tcm-DMSA renal uptake at 24 h in children with a normal scintigram. NUCLEAR MEDICINE COMMUNICATIONS. 1998;19(2):149–54.
MLA
Van De Wiele, Christophe, Maria Simons, Johan Vande Walle, et al. “Age- and Sex-related 99Tcm-DMSA Renal Uptake at 24 h in Children with a Normal Scintigram.” NUCLEAR MEDICINE COMMUNICATIONS 19.2 (1998): 149–154. Print.
@article{176648,
  abstract     = {We performed a retrospective study to determine the age-and sex-related normal values of absolute Tc-99(m)-DMSA uptake at 24 h in children with normal kidneys. Of the 576 scintigrams performed between 1993 and 1996, 136 (272 kidneys) were classified as `normal' by two independent observers on the basis of the presence of a smooth cortical outline, the absence of cortical loss, relative uptake in the range 45-55\% and normal echographic parenchymal findings. The 136 scintigrams were divided into eight groups based on the children's age: Group I,,{\textlangle}1 month (2 boys); Group II, 1-3 months (6 boys, 8 girls); Group III, 4-7 months (7 boys, 6 girls); Group IV, 8-12 months (8 boys, 8 girls); Group V, 13-24 months (14 boys, 4 girls); Group VI, 25-36 months (6 boys, 13 girls); Group VII, 37-120 months (13 boys, 19 girls); Group VIII, 121-180 months (8 boys, 10 girls). In contrast to the results of Morris et al. using absolute Tc-99(m)-DMSA uptake at 4-6 h, we found that combined left and right kidney uptake increased until age 8 months (Group I, 22.0 +/- 6.7\%; Group II, 45.9 +/- 5.0\%; Group III, 50.8 +/- 5.0\%; Group IV, 56.9 +/- 8.5\%; P=0.019), after which it reached a plateau (Group V, 55.4 +/- 7.3\%; Group VI, 60.1 +/- 7.8\%; Group VII, 62.0 +/- 5.0\%; Group VIII, 62.4 +/- 6.3\%). Uptake at 24 h tended to be lower in the girls than in the boys, but this difference was not significant.},
  author       = {Van De Wiele, Christophe and Simons, Maria and Vande Walle, Johan and De Sutter, Johan and Everaert, Karel and Dierckx, Rudi},
  issn         = {0143-3636},
  journal      = {NUCLEAR MEDICINE COMMUNICATIONS},
  keyword      = {FLOW},
  language     = {eng},
  number       = {2},
  pages        = {149--154},
  title        = {Age- and sex-related 99Tcm-DMSA renal uptake at 24 h in children with a normal scintigram},
  volume       = {19},
  year         = {1998},
}

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