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Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana

(1998) NATURE. 391(6666). p.485-488
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Abstract
The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology(1). The relatively small size of the nuclear genome and the availability of extensive physical maps of the five chromosomes(2-4) provide a feasible basis for initiating sequencing of the five chromosomes. The YAC (yeast artificial chromosome)-based physical map of chromosome 4 was used to construct a sequence-ready map of cosmid and BAC (bacterial artificial chromosome) clones covering a 1,9-megabase (Mb) contiguous region(5), and the sequence of this region is reported here. Analysis of the sequence revealed an average gene density of one gene every 4.8 kilobases (kb), and 54% of the predicted genes had significant similarity to known genes. Other interesting features were found, such as the sequence of a disease-resistance gene locus, the distribution of retroelements, the frequent occurrence of clustered gene families, and the sequence of several classes of genes not previously encountered in plants.
Keywords
ASSOCIATION, RETROTRANSPOSONS, EXPRESSION, EVOLUTION, REGIONS, PROTEIN, GENOME, GENES, PHYSICAL MAP

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Chicago
Bevan, M, I Bancroft, E Bent, K Love, H Goodman, C Dean, R Bergkamp, et al. 1998. “Analysis of 1.9 Mb of Contiguous Sequence from Chromosome 4 of Arabidopsis Thaliana.” Nature 391 (6666): 485–488.
APA
Bevan, M, Bancroft, I., Bent, E., Love, K., Goodman, H., Dean, C., Bergkamp, R., et al. (1998). Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. NATURE, 391(6666), 485–488.
Vancouver
1.
Bevan M, Bancroft I, Bent E, Love K, Goodman H, Dean C, et al. Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. NATURE. 1998;391(6666):485–8.
MLA
Bevan, M, I Bancroft, E Bent, et al. “Analysis of 1.9 Mb of Contiguous Sequence from Chromosome 4 of Arabidopsis Thaliana.” NATURE 391.6666 (1998): 485–488. Print.
@article{176285,
  abstract     = {The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology(1). The relatively small size of the nuclear genome and the availability of extensive physical maps of the five chromosomes(2-4) provide a feasible basis for initiating sequencing of the five chromosomes. The YAC (yeast artificial chromosome)-based physical map of chromosome 4 was used to construct a sequence-ready map of cosmid and BAC (bacterial artificial chromosome) clones covering a 1,9-megabase (Mb) contiguous region(5), and the sequence of this region is reported here. Analysis of the sequence revealed an average gene density of one gene every 4.8 kilobases (kb), and 54\% of the predicted genes had significant similarity to known genes. Other interesting features were found, such as the sequence of a disease-resistance gene locus, the distribution of retroelements, the frequent occurrence of clustered gene families, and the sequence of several classes of genes not previously encountered in plants.},
  author       = {Bevan, M and Bancroft, I and Bent, E and Love, K and Goodman, H and Dean, C and Bergkamp, R and Dirkse, W and Van Staveren, M and Stiekema, W and Drost, L and Ridley, P and Hudson, S-A and Patel, K and Murphy, G and Piffanelli, P and Wedler, H and Wedler, E and Wambutt, R and Weitzenegger, T and Pohl, TM and Terryn, Nancy and Gielen, Jan and Villarroel-Mandiola, Raimundo and De Clerck, R and Van Montagu, Marc and Lecharny, A and Auborg, S and Gy, I and Kreis, M and Lao, N and Kavanagh, T and Hempel, S and Kotter, P and Entian, K-D and Rieger, M and Schaeffer, M and Funk, B and Mueller-Auer, S and Silvey, M and James, R and Montfort, A and Pons, A and Puigdomenech, P and Douka, A and Voukelatou, E and Milioni, D and Hatzopoulos, P and Piravandi, E and Obermaier, B and Hilbert, H and D{\"u}sterh{\"o}ft, A and Moores, T and Jones, JDG and Eneva, T and Palme, K and Benes, V and Rechman, S and Ansorge, W and Cooke, R and Berger, C and Delseny, M and Voet, M and Volckaert, G and Mewes, H-W and Klosterman, S and Schueller, C and Chalwatzis, N},
  issn         = {0028-0836},
  journal      = {NATURE},
  language     = {eng},
  number       = {6666},
  pages        = {485--488},
  title        = {Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana},
  url          = {http://dx.doi.org/10.1038/35140},
  volume       = {391},
  year         = {1998},
}

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