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Inhibition in vitro d'enzymes digestives par les tanins condensés du sorgho (Sorghum bicolor L. (Moench))

K Nguz, Dirk Van Gaver and André Huyghebaert (UGent)
(1998) SCIENCES DES ALIMENTS. 18(5). p.507-514
Author
Organization
Abstract
Sorghum condensed tannins (proanthocyanidins) from a birdproof variety, strongly inhibit digestive enzymes in vitro, namely alpha-amylase and trypsine, even at low concentrations. This inhibition is correlated with the concentration of condensed tannins according to a quadratric relation for both enzymes. The analysis of the nature of inhibition by the double reciprocal method of LINEWEAVER-BURK shows that the inhibitor acts on the velocity of reaction and that this inhibition is non-competitive. These findings could explain the low dry matter and protein digestibility of food containing condensed tannins, which has been observed in vivo and in vitro.
Keywords
tanin, alpha-amylase, trypsine, inhibition, in vitro, PROTEINS, BINDING

Citation

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MLA
Nguz, K., et al. “Inhibition in Vitro d’enzymes Digestives Par Les Tanins Condensés Du Sorgho (Sorghum Bicolor L. (Moench)).” SCIENCES DES ALIMENTS, vol. 18, no. 5, 1998, pp. 507–14.
APA
Nguz, K., Van Gaver, D., & Huyghebaert, A. (1998). Inhibition in vitro d’enzymes digestives par les tanins condensés du sorgho (Sorghum bicolor L. (Moench)). SCIENCES DES ALIMENTS, 18(5), 507–514.
Chicago author-date
Nguz, K, Dirk Van Gaver, and André Huyghebaert. 1998. “Inhibition in Vitro d’enzymes Digestives Par Les Tanins Condensés Du Sorgho (Sorghum Bicolor L. (Moench)).” SCIENCES DES ALIMENTS 18 (5): 507–14.
Chicago author-date (all authors)
Nguz, K, Dirk Van Gaver, and André Huyghebaert. 1998. “Inhibition in Vitro d’enzymes Digestives Par Les Tanins Condensés Du Sorgho (Sorghum Bicolor L. (Moench)).” SCIENCES DES ALIMENTS 18 (5): 507–514.
Vancouver
1.
Nguz K, Van Gaver D, Huyghebaert A. Inhibition in vitro d’enzymes digestives par les tanins condensés du sorgho (Sorghum bicolor L. (Moench)). SCIENCES DES ALIMENTS. 1998;18(5):507–14.
IEEE
[1]
K. Nguz, D. Van Gaver, and A. Huyghebaert, “Inhibition in vitro d’enzymes digestives par les tanins condensés du sorgho (Sorghum bicolor L. (Moench)),” SCIENCES DES ALIMENTS, vol. 18, no. 5, pp. 507–514, 1998.
@article{173224,
  abstract     = {{Sorghum condensed tannins (proanthocyanidins) from a birdproof variety, strongly inhibit digestive enzymes in vitro, namely alpha-amylase and trypsine, even at low concentrations. This inhibition is correlated with the concentration of condensed tannins according to a quadratric relation for both enzymes. The analysis of the nature of inhibition by the double reciprocal method of LINEWEAVER-BURK shows that the inhibitor acts on the velocity of reaction and that this inhibition is non-competitive. These findings could explain the low dry matter and protein digestibility of food containing condensed tannins, which has been observed in vivo and in vitro.}},
  author       = {{Nguz, K and Van Gaver, Dirk and Huyghebaert, André}},
  issn         = {{0240-8813}},
  journal      = {{SCIENCES DES ALIMENTS}},
  keywords     = {{tanin,alpha-amylase,trypsine,inhibition,in vitro,PROTEINS,BINDING}},
  language     = {{fre}},
  number       = {{5}},
  pages        = {{507--514}},
  title        = {{Inhibition in vitro d'enzymes digestives par les tanins condensés du sorgho (Sorghum bicolor L. (Moench))}},
  volume       = {{18}},
  year         = {{1998}},
}
Web of Science
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