Encoding microcarriers : present and future technologies
- Author
- Kevin Braeckmans (UGent) , Stefaan De Smedt (UGent) , Marc Leblans, Romain Pauwels and Jo Demeester (UGent)
- Organization
- Abstract
- In answer to the ever-increasing need to carry out many assays simultaneously in drug screening and drug discovery, several microcarrier-based multiplex technologies have arisen in the past few years. The compounds to be screened are attached to the surface of microcarriers, which can be mixed together in a vessel that contains the target analyte. Each microcarrier has to be encoded to know which compound is attached to its surface. In this article, the methods that have been developed for the encoding of microcarriers are reviewed and discussed.
- Keywords
- COMBINATORIAL LIBRARY METHOD, NUCLEOTIDE POLYMORPHISM ANALYSIS, FLIGHT MASS-SPECTROMETRY, FLOW CYTOMETRIC ASSAY, HERPES-SIMPLEX VIRUS, GENE-EXPRESSION, FLOWMETRIX(TM) SYSTEM, MULTIPLEXED ANALYSIS, CHEMICAL LIBRARIES, DNA ARRAYS
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-149544
- MLA
- Braeckmans, Kevin, et al. “Encoding Microcarriers : Present and Future Technologies.” NATURE REVIEWS DRUG DISCOVERY, vol. 1, no. 6, 2002, pp. 447–56, doi:10.1038/nrd817.
- APA
- Braeckmans, K., De Smedt, S., Leblans, M., Pauwels, R., & Demeester, J. (2002). Encoding microcarriers : present and future technologies. NATURE REVIEWS DRUG DISCOVERY, 1(6), 447–456. https://doi.org/10.1038/nrd817
- Chicago author-date
- Braeckmans, Kevin, Stefaan De Smedt, Marc Leblans, Romain Pauwels, and Jo Demeester. 2002. “Encoding Microcarriers : Present and Future Technologies.” NATURE REVIEWS DRUG DISCOVERY 1 (6): 447–56. https://doi.org/10.1038/nrd817.
- Chicago author-date (all authors)
- Braeckmans, Kevin, Stefaan De Smedt, Marc Leblans, Romain Pauwels, and Jo Demeester. 2002. “Encoding Microcarriers : Present and Future Technologies.” NATURE REVIEWS DRUG DISCOVERY 1 (6): 447–456. doi:10.1038/nrd817.
- Vancouver
- 1.Braeckmans K, De Smedt S, Leblans M, Pauwels R, Demeester J. Encoding microcarriers : present and future technologies. NATURE REVIEWS DRUG DISCOVERY. 2002;1(6):447–56.
- IEEE
- [1]K. Braeckmans, S. De Smedt, M. Leblans, R. Pauwels, and J. Demeester, “Encoding microcarriers : present and future technologies,” NATURE REVIEWS DRUG DISCOVERY, vol. 1, no. 6, pp. 447–456, 2002.
@article{149544,
abstract = {{In answer to the ever-increasing need to carry out many assays simultaneously in drug screening and drug discovery, several microcarrier-based multiplex technologies have arisen in the past few years. The compounds to be screened are attached to the surface of microcarriers, which can be mixed together in a vessel that contains the target analyte. Each microcarrier has to be encoded to know which compound is attached to its surface. In this article, the methods that have been developed for the encoding of microcarriers are reviewed and discussed.}},
author = {{Braeckmans, Kevin and De Smedt, Stefaan and Leblans, Marc and Pauwels, Romain and Demeester, Jo}},
issn = {{1474-1776}},
journal = {{NATURE REVIEWS DRUG DISCOVERY}},
keywords = {{COMBINATORIAL LIBRARY METHOD,NUCLEOTIDE POLYMORPHISM ANALYSIS,FLIGHT MASS-SPECTROMETRY,FLOW CYTOMETRIC ASSAY,HERPES-SIMPLEX VIRUS,GENE-EXPRESSION,FLOWMETRIX(TM) SYSTEM,MULTIPLEXED ANALYSIS,CHEMICAL LIBRARIES,DNA ARRAYS}},
language = {{eng}},
number = {{6}},
pages = {{447--456}},
title = {{Encoding microcarriers : present and future technologies}},
url = {{http://doi.org/10.1038/nrd817}},
volume = {{1}},
year = {{2002}},
}
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