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Dosimetry of 192Ir sources used for endovascular brachytherapy

Nick Reynaert, Marc Van Eijkeren UGent, Yvo Taeymans and Hubert Thierens UGent (2001) PHYSICS IN MEDICINE AND BIOLOGY. 46(2). p.499-516
abstract
An in-phantom calibration technique for Ir-192 sources used for endovascular brachytherapy is presented. Three different source lengths were investigated. The calibration was performed in a solid phantom using a Farmer-type ionization chamber at source to detector distances ranging from I cm to 5 cm. The dosimetry protocol for medium-energy x-rays extended with a volume-averaging correction factor was used to convert the chamber reading to dose to water. The air kerma strength of the sources was determined as well. EGS4 Monte Carlo calculations were performed to determine the depth dose distribution at distances ranging from 0.6 mm to 10 cm from the source centre. In this way we were able to convert the absolute dose rate at 1 cm distance to the reference point chosen at 2 mm distance. The Monte Carlo results were confirmed by radiochromic film measurements, performed with a double-exposure technique. The dwell times to deliver a dose of 14 Gy at the reference point were determined and compared with results given by the source supplier (CORDIS). They determined the dwell times from a Sievert integration technique based on the source activity. The results from both methods agreed to within 2% for the 12 sources that were evaluated. A Visual Basic routine that superimposes dose distributions, based on the Monte Carlo calculations and the in-phantom calibration, onto intravascular ultrasound images is presented. This routine can be used as an online treatment planning program.
Please use this url to cite or link to this publication:
author
organization
alternative title
Dosimetry of Ir-192 sources used for endovascular brachytherapy
year
type
journalArticle (original)
publication status
published
subject
keyword
INTRAVASCULAR BRACHYTHERAPY, CALIBRATION, P-32, STENT
journal title
PHYSICS IN MEDICINE AND BIOLOGY
Phys. Med. Biol.
volume
46
issue
2
pages
499 - 516
Web of Science type
Article
Web of Science id
000167070200016
JCR category
ENGINEERING, BIOMEDICAL
JCR impact factor
1.805 (2001)
JCR rank
5/39 (2001)
JCR quartile
1 (2001)
ISSN
0031-9155
DOI
10.1088/0031-9155/46/2/316
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
141621
handle
http://hdl.handle.net/1854/LU-141621
date created
2004-01-14 13:37:00
date last changed
2016-12-19 15:38:06
@article{141621,
  abstract     = {An in-phantom calibration technique for Ir-192 sources used for endovascular brachytherapy is presented. Three different source lengths were investigated. The calibration was performed in a solid phantom using a Farmer-type ionization chamber at source to detector distances ranging from I cm to 5 cm. The dosimetry protocol for medium-energy x-rays extended with a volume-averaging correction factor was used to convert the chamber reading to dose to water. The air kerma strength of the sources was determined as well. EGS4 Monte Carlo calculations were performed to determine the depth dose distribution at distances ranging from 0.6 mm to 10 cm from the source centre. In this way we were able to convert the absolute dose rate at 1 cm distance to the reference point chosen at 2 mm distance. The Monte Carlo results were confirmed by radiochromic film measurements, performed with a double-exposure technique. The dwell times to deliver a dose of 14 Gy at the reference point were determined and compared with results given by the source supplier (CORDIS). They determined the dwell times from a Sievert integration technique based on the source activity. The results from both methods agreed to within 2\% for the 12 sources that were evaluated. A Visual Basic routine that superimposes dose distributions, based on the Monte Carlo calculations and the in-phantom calibration, onto intravascular ultrasound images is presented. This routine can be used as an online treatment planning program.},
  author       = {Reynaert, Nick and Van Eijkeren, Marc and Taeymans, Yvo and Thierens, Hubert},
  issn         = {0031-9155},
  journal      = {PHYSICS IN MEDICINE AND BIOLOGY},
  keyword      = {INTRAVASCULAR BRACHYTHERAPY,CALIBRATION,P-32,STENT},
  language     = {eng},
  number       = {2},
  pages        = {499--516},
  title        = {Dosimetry of 192Ir sources used for endovascular brachytherapy},
  url          = {http://dx.doi.org/10.1088/0031-9155/46/2/316},
  volume       = {46},
  year         = {2001},
}

Chicago
Reynaert, Nick, Marc Van Eijkeren, Yvo Taeymans, and Hubert Thierens. 2001. “Dosimetry of 192Ir Sources Used for Endovascular Brachytherapy.” Physics in Medicine and Biology 46 (2): 499–516.
APA
Reynaert, N., Van Eijkeren, M., Taeymans, Y., & Thierens, H. (2001). Dosimetry of 192Ir sources used for endovascular brachytherapy. PHYSICS IN MEDICINE AND BIOLOGY, 46(2), 499–516.
Vancouver
1.
Reynaert N, Van Eijkeren M, Taeymans Y, Thierens H. Dosimetry of 192Ir sources used for endovascular brachytherapy. PHYSICS IN MEDICINE AND BIOLOGY. 2001;46(2):499–516.
MLA
Reynaert, Nick, Marc Van Eijkeren, Yvo Taeymans, et al. “Dosimetry of 192Ir Sources Used for Endovascular Brachytherapy.” PHYSICS IN MEDICINE AND BIOLOGY 46.2 (2001): 499–516. Print.