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Ovarian tissue cryopreservation: therapeutic prospects and ethical reflections

Rudy Van den Broecke UGent, Guido Pennings UGent, Jun Liu, Josiane Van der Elst UGent and Marc Dhont (2001) Reproductive Biomedicine Online. 3(3). p.177-182
abstract
Along with improved survival, methods to preserve or restore the fertility potential of young women and children treated with cytotoxic chemotherapy or pelvic radiotherapy have been developed or are in the offing. Surgery, radiotherapy and chemotherapy can all impact on the future ovarian function, but patient and disease tailored application and use of preventive measures can limit ovarian damage. When the loss of reproductive ovarian function is unavoidable, different alternatives to preserve fertility or at least to restore the procreative potential are available. Creation of embryos by IVF, oocyte donation and cryopreservation of mature or immature oocytes are potential issues, the advantages and limitations of which are discussed. Recently, ovarian tissue cryopreservation has spurred interest in the medical literature as well as in the lay press as a method for preservation and restoring fertility. Considering the available data and current state of knowledge, we want to stress that this methodology is still in an experimental phase and we would like to caution against unwarranted enthusiasm of physicians and patients. The medical information preceding the informed consent should mention the actual uncertainties of this method. Moreover, the imperative character of the offer and in particular for paediatric oncological patients, the force of the moral rules that define parental obligations towards children should not be ignored.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
journal title
Reproductive Biomedicine Online
Reprod. biomed. online
volume
3
issue
3
pages
177 - 182
ISSN
1472-6491
language
English
UGent publication?
yes
classification
A2
VABB id
c:vabb:77440
VABB type
VABB-1
id
141582
handle
http://hdl.handle.net/1854/LU-141582
date created
2004-01-14 13:37:00
date last changed
2016-12-19 15:38:06
@article{141582,
  abstract     = {Along with improved survival, methods to preserve or restore the fertility potential of young women and children treated with cytotoxic chemotherapy or pelvic radiotherapy have been developed or are in the offing. Surgery, radiotherapy and chemotherapy can all impact on the future ovarian function, but patient and disease tailored application and use of preventive measures can limit ovarian damage. When the loss of reproductive ovarian function is unavoidable, different alternatives to preserve fertility or at least to restore the procreative potential are available. Creation of embryos by IVF, oocyte donation and cryopreservation of mature or immature oocytes are potential issues, the advantages and limitations of which are discussed. Recently, ovarian tissue cryopreservation has spurred interest in the medical literature as well as in the lay press as a method for preservation and restoring fertility. Considering the available data and current state of knowledge, we want to stress that this methodology is still in an experimental phase and we would like to caution against unwarranted enthusiasm of physicians and patients. The medical information preceding the informed consent should mention the actual uncertainties of this method. Moreover, the imperative character of the offer and in particular for paediatric oncological patients, the force of the moral rules that define parental obligations towards children should not be ignored.},
  author       = {Van den Broecke, Rudy and Pennings, Guido and Liu, Jun and Van der Elst, Josiane and Dhont, Marc},
  issn         = {1472-6491},
  journal      = {Reproductive Biomedicine Online},
  language     = {eng},
  number       = {3},
  pages        = {177--182},
  title        = {Ovarian tissue cryopreservation: therapeutic prospects and ethical reflections},
  volume       = {3},
  year         = {2001},
}

Chicago
Van den Broecke, Rudy, Guido Pennings, Jun Liu, Josiane Van der Elst, and MARC DHONT. 2001. “Ovarian Tissue Cryopreservation: Therapeutic Prospects and Ethical Reflections.” Reproductive Biomedicine Online 3 (3): 177–182.
APA
Van den Broecke, R., Pennings, G., Liu, J., Van der Elst, J., & DHONT, M. (2001). Ovarian tissue cryopreservation: therapeutic prospects and ethical reflections. Reproductive Biomedicine Online, 3(3), 177–182.
Vancouver
1.
Van den Broecke R, Pennings G, Liu J, Van der Elst J, DHONT M. Ovarian tissue cryopreservation: therapeutic prospects and ethical reflections. Reproductive Biomedicine Online. 2001;3(3):177–82.
MLA
Van den Broecke, Rudy, Guido Pennings, Jun Liu, et al. “Ovarian Tissue Cryopreservation: Therapeutic Prospects and Ethical Reflections.” Reproductive Biomedicine Online 3.3 (2001): 177–182. Print.