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Long term results of cardioverter-defibrillator implantation in patients with right ventricular dysplasia and malignant ventricular tachyarrhythmias

(2001) HEART. 85(1). p.53-56
Author
Organization
Abstract
Objective: To study the outcome of patients with arrhythmogenic right ventricular dysplasia treated with an implantable cardioverter-defibrillator (ICD) for ventricular tachyarrhythmias complicated by haemodynamic collapse. Design: Observational study. Setting: University hospital. Patients: Nine consecutive patients (eight male, one female; mean (SD) age, 36 (18) years) with arrhythmogenic right ventricular dysplasia presenting with ventricular tachycardia and haemodynamic collapse (n = 6) or ventricular fibrillation (n = 3), treated with an ICD. Main outcome measures: Survival; numbers of and reasons for appropriate and inappropriate ICD interventions. Results: After a mean (SD) follow up of 32 (24) months, all patients were alive. Six patients received a median of 19 (range 2-306) appropriate ICD interventions for events detected in the ventricular tachycardia window; four received a median of 2 (range 1-19) appropriate ICD interventions for events detected in the ventricular fibrillation window. Inappropriate interventions were seen for sinus tachycardia (18 episodes in three patients), atrial fibrillation (three episodes in one patient), and for non-sustained polymorphic ventricular tachycardia tone episode in one patient). Conclusions: Patients with arrhythmogenic right ventricular dysplasia and malignant ventricular arrhythmias have a high recurrence rate requiring appropriate ICD interventions, but they also often have inappropriate interventions. Programming the device is difficult because this population develops supraventricular and ventricular tachyarrhythmias with similar rates.
Keywords
implantable cardioverter defibrillator, arrhythmogenic right ventricular dysplasia, arrhythmia, CARDIOMYOPATHY, TACHYCARDIA, THERAPY, DISEASE

Citation

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Chicago
Tavernier, René, S Gevaert, Johan De Sutter, A De Clercq, H Rottiers, Luc Jordaens, and Winoc Fonteyne. 2001. “Long Term Results of Cardioverter-defibrillator Implantation in Patients with Right Ventricular Dysplasia and Malignant Ventricular Tachyarrhythmias.” Heart 85 (1): 53–56.
APA
Tavernier, René, Gevaert, S., De Sutter, J., De Clercq, A., Rottiers, H., Jordaens, L., & Fonteyne, W. (2001). Long term results of cardioverter-defibrillator implantation in patients with right ventricular dysplasia and malignant ventricular tachyarrhythmias. HEART, 85(1), 53–56.
Vancouver
1.
Tavernier R, Gevaert S, De Sutter J, De Clercq A, Rottiers H, Jordaens L, et al. Long term results of cardioverter-defibrillator implantation in patients with right ventricular dysplasia and malignant ventricular tachyarrhythmias. HEART. 2001;85(1):53–6.
MLA
Tavernier, René, S Gevaert, Johan De Sutter, et al. “Long Term Results of Cardioverter-defibrillator Implantation in Patients with Right Ventricular Dysplasia and Malignant Ventricular Tachyarrhythmias.” HEART 85.1 (2001): 53–56. Print.
@article{140744,
  abstract     = {Objective: To study the outcome of patients with arrhythmogenic right ventricular dysplasia treated with an implantable cardioverter-defibrillator (ICD) for ventricular tachyarrhythmias complicated by haemodynamic collapse. 
Design: Observational study. 
Setting: University hospital. 
Patients: Nine consecutive patients (eight male, one female; mean (SD) age, 36 (18) years) with arrhythmogenic right ventricular dysplasia presenting with ventricular tachycardia and haemodynamic collapse (n = 6) or ventricular fibrillation (n = 3), treated with an ICD. 
Main outcome measures: Survival; numbers of and reasons for appropriate and inappropriate ICD interventions. 
Results: After a mean (SD) follow up of 32 (24) months, all patients were alive. Six patients received a median of 19 (range 2-306) appropriate ICD interventions for events detected in the ventricular tachycardia window; four received a median of 2 (range 1-19) appropriate ICD interventions for events detected in the ventricular fibrillation window. Inappropriate interventions were seen for sinus tachycardia (18 episodes in three patients), atrial fibrillation (three episodes in one patient), and for non-sustained polymorphic ventricular tachycardia tone episode in one patient). 
Conclusions: Patients with arrhythmogenic right ventricular dysplasia and malignant ventricular arrhythmias have a high recurrence rate requiring appropriate ICD interventions, but they also often have inappropriate interventions. Programming the device is difficult because this population develops supraventricular and ventricular tachyarrhythmias with similar rates.},
  author       = {Tavernier, Ren{\'e} and Gevaert, S and De Sutter, Johan and De Clercq, A and Rottiers, H and Jordaens, Luc and Fonteyne, Winoc},
  issn         = {1355-6037},
  journal      = {HEART},
  keyword      = {implantable cardioverter defibrillator,arrhythmogenic right ventricular dysplasia,arrhythmia,CARDIOMYOPATHY,TACHYCARDIA,THERAPY,DISEASE},
  language     = {eng},
  number       = {1},
  pages        = {53--56},
  title        = {Long term results of cardioverter-defibrillator implantation in patients with right ventricular dysplasia and malignant ventricular tachyarrhythmias},
  volume       = {85},
  year         = {2001},
}

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