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Decreased neutrophil bactericidal activity during phagocytosis of a slime-producing Staphylococcus aureus strain.

(2000) VETERINARY RESEARCH. 31(6). p.603-609
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Abstract
Phagocytosis and intracellular killing by bovine polymorphonuclear leukocytes (PMN) are important host defence mechanisms against mastitis caused by Staphylococcus aureus. We compared the phagocytosis and overall killing of a non slime-producing (NSP) S. aureus and its slime-producing (SP) variant by blood PMN, using an in vitro bacteriological assay. Seven clinically healthy Holstein-Friesian dairy cows in mid-lactation stage were used for this purpose. The percentages of overall killing for the NSP and SP variant were 34 +/- 3% and 21 +/- 4% (P < 0.05) and the corresponding percentages of phagocytosis were 40 +/- 4% and 31 +/- 4%, respectively. A significant positive correlation (r = 0.79; P < 0.001) was found between phagocytosis and overall killing. These results suggest that the presence of slime was responsible for a decreased phagocytic ingestion and overall killing.
Keywords
Staphylococcus aureus, bovine blood neutrophil, slime, bacteriological assay, HUMAN POLYMORPHONUCLEAR LEUKOCYTES, BOVINE NEUTROPHILS, PHASE VARIATION, COMPLEMENT, EPIDERMIDIS, RESISTANCE, VIRULENCE, ADHERENCE, MASTITIS, MILK

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Chicago
Barrio, Belén, Frédéric Vangroenweghe, Hilde Dosogne, and Christian Burvenich. 2000. “Decreased Neutrophil Bactericidal Activity During Phagocytosis of a Slime-producing Staphylococcus Aureus Strain.” Veterinary Research 31 (6): 603–609.
APA
Barrio, Belén, Vangroenweghe, F., Dosogne, H., & Burvenich, C. (2000). Decreased neutrophil bactericidal activity during phagocytosis of a slime-producing Staphylococcus aureus strain. VETERINARY RESEARCH, 31(6), 603–609.
Vancouver
1.
Barrio B, Vangroenweghe F, Dosogne H, Burvenich C. Decreased neutrophil bactericidal activity during phagocytosis of a slime-producing Staphylococcus aureus strain. VETERINARY RESEARCH. 2000;31(6):603–9.
MLA
Barrio, Belén, Frédéric Vangroenweghe, Hilde Dosogne, et al. “Decreased Neutrophil Bactericidal Activity During Phagocytosis of a Slime-producing Staphylococcus Aureus Strain.” VETERINARY RESEARCH 31.6 (2000): 603–609. Print.
@article{131442,
  abstract     = {Phagocytosis and intracellular killing by bovine polymorphonuclear leukocytes (PMN) are important host defence mechanisms against mastitis caused by Staphylococcus aureus. We compared the phagocytosis and overall killing of a non slime-producing (NSP) S. aureus and its slime-producing (SP) variant by blood PMN, using an in vitro bacteriological assay. Seven clinically healthy Holstein-Friesian dairy cows in mid-lactation stage were used for this purpose. The percentages of overall killing for the NSP and SP variant were 34 +/- 3\% and 21 +/- 4\% (P {\textlangle} 0.05) and the corresponding percentages of phagocytosis were 40 +/- 4\% and 31 +/- 4\%, respectively. A significant positive correlation (r = 0.79; P {\textlangle} 0.001) was found between phagocytosis and overall killing. These results suggest that the presence of slime was responsible for a decreased phagocytic ingestion and overall killing.},
  author       = {Barrio, Bel{\'e}n and Vangroenweghe, Fr{\'e}d{\'e}ric and Dosogne, Hilde and Burvenich, Christian},
  issn         = {0928-4249},
  journal      = {VETERINARY RESEARCH},
  keyword      = {Staphylococcus aureus,bovine blood neutrophil,slime,bacteriological assay,HUMAN POLYMORPHONUCLEAR LEUKOCYTES,BOVINE NEUTROPHILS,PHASE VARIATION,COMPLEMENT,EPIDERMIDIS,RESISTANCE,VIRULENCE,ADHERENCE,MASTITIS,MILK},
  language     = {eng},
  number       = {6},
  pages        = {603--609},
  title        = {Decreased neutrophil bactericidal activity during phagocytosis of a slime-producing Staphylococcus aureus strain.},
  volume       = {31},
  year         = {2000},
}

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