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18-Fluorodeoxyglucose positron emission tomography as a tool for response prediction in solid tumours

DAAN DE MAESENEER UGent, Bieke Lambert UGent, Veerle Surmont UGent, Karen Geboes UGent and Sylvie Rottey UGent (2010) ACTA CLINICA BELGICA. 65(5). p.291-299
abstract
Current response guidelines for the treatment of solid tumours are based on CT criteria. Over the last decades new techniques have emerged to evaluate cancer therapy. FDG-PET scanning is a more functional imaging technique, which can measure differences in metabolic activity. Although it has a low specificity, studies show that it can outperform classical CT scanning criteria. Especially in lung, breast and oesophageal cancer it can predict response earlier in the neo-adjuvant setting. This could reduce the use of ineffective cancer therapies, reducing costs and patient toxicity, and direct patients sooner towards effective therapy. The main problem with FDG-PET remains the difficulty in defining thresholds for response, as there is clearly a lack in large prospective randomized studies validating the use of FDG-PET in response guidelines. We give an overview of data on response prediction in solid tumours by the application of PET.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
response prediction, cancer, FDG-PET, CELL LUNG-CANCER, ADVANCED RECTAL-CANCER, BREAST-CANCER, NECK-CANCER, PREOPERATIVE CHEMOTHERAPY, NEOADJUVANT CHEMOTHERAPY, PATHOLOGICAL RESPONSE, RADICAL RADIOTHERAPY, COLORECTAL-CANCER
journal title
ACTA CLINICA BELGICA
Acta Clin. Belg.
volume
65
issue
5
pages
291 - 299
Web of Science type
Article
Web of Science id
000283674000001
JCR category
MEDICINE, GENERAL & INTERNAL
JCR impact factor
0.532 (2010)
JCR rank
104/151 (2010)
JCR quartile
3 (2010)
ISSN
0001-5512
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1262174
handle
http://hdl.handle.net/1854/LU-1262174
date created
2011-06-14 15:28:15
date last changed
2011-06-21 14:14:08
@article{1262174,
  abstract     = {Current response guidelines for the treatment of solid tumours are based on CT criteria. Over the last decades new techniques have emerged to evaluate cancer therapy. FDG-PET scanning is a more functional imaging technique, which can measure differences in metabolic activity. Although it has a low specificity, studies show that it can outperform classical CT scanning criteria. Especially in lung, breast and oesophageal cancer it can predict response earlier in the neo-adjuvant setting. This could reduce the use of ineffective cancer therapies, reducing costs and patient toxicity, and direct patients sooner towards effective therapy. The main problem with FDG-PET remains the difficulty in defining thresholds for response, as there is clearly a lack in large prospective randomized studies validating the use of FDG-PET in response guidelines. We give an overview of data on response prediction in solid tumours by the application of PET.},
  author       = {DE MAESENEER, DAAN and Lambert, Bieke and Surmont, Veerle and Geboes, Karen and Rottey, Sylvie},
  issn         = {0001-5512},
  journal      = {ACTA CLINICA BELGICA},
  keyword      = {response prediction,cancer,FDG-PET,CELL LUNG-CANCER,ADVANCED RECTAL-CANCER,BREAST-CANCER,NECK-CANCER,PREOPERATIVE CHEMOTHERAPY,NEOADJUVANT CHEMOTHERAPY,PATHOLOGICAL RESPONSE,RADICAL RADIOTHERAPY,COLORECTAL-CANCER},
  language     = {eng},
  number       = {5},
  pages        = {291--299},
  title        = {18-Fluorodeoxyglucose positron emission tomography as a tool for response prediction in solid tumours},
  volume       = {65},
  year         = {2010},
}

Chicago
DE MAESENEER, DAAN, Bieke Lambert, VEERLE SURMONT, Karen Geboes, and Sylvie Rottey. 2010. “18-Fluorodeoxyglucose Positron Emission Tomography as a Tool for Response Prediction in Solid Tumours.” Acta Clinica Belgica 65 (5): 291–299.
APA
DE MAESENEER, D., Lambert, B., SURMONT, V., Geboes, K., & Rottey, S. (2010). 18-Fluorodeoxyglucose positron emission tomography as a tool for response prediction in solid tumours. ACTA CLINICA BELGICA, 65(5), 291–299.
Vancouver
1.
DE MAESENEER D, Lambert B, SURMONT V, Geboes K, Rottey S. 18-Fluorodeoxyglucose positron emission tomography as a tool for response prediction in solid tumours. ACTA CLINICA BELGICA. 2010;65(5):291–9.
MLA
DE MAESENEER, DAAN, Bieke Lambert, VEERLE SURMONT, et al. “18-Fluorodeoxyglucose Positron Emission Tomography as a Tool for Response Prediction in Solid Tumours.” ACTA CLINICA BELGICA 65.5 (2010): 291–299. Print.