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Engaging neuroscience to advance translational research in brain barrier biology

Edward A Neuwelt, Björn Bauer, Christoph Fahlke, Gert Fricker, Constantino Iadecola, Damir Janigro, Luc Leybaert UGent, Zoltan Molnar, Martha O’Donnell and John Povlishock, et al. (2011) NATURE REVIEWS NEUROSCIENCE. 12(3). p.169-182
abstract
The delivery of many potentially therapeutic and diagnostic compounds to specific areas of the brain is restricted by brain barriers, of which the most well known are the blood-brain barrier (BBB) and the blood-cerebrospinal fluid (CSF) barrier. Recent studies have shown numerous additional roles of these barriers, including an involvement in neurodevelopment, in the control of cerebral blood flow, and-when barrier integrity is impaired-in the pathology of many common CNS disorders such as Alzheimer's disease, Parkinson's disease and stroke.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
MULTIPLE-SCLEROSIS, INDUCED UP-REGULATION, CENTRAL-NERVOUS-SYSTEM, NECROSIS-FACTOR-ALPHA, AMINO-ACID TRANSPORTERS, HEREDITARY CEREBRAL-HEMORRHAGE, GREEN FLUORESCENT PROTEIN, BINDING CASSETTE TRANSPORTERS, P-GLYCOPROTEIN EXPRESSION, HUMAN BLOOD-BRAIN
journal title
NATURE REVIEWS NEUROSCIENCE
Nat. Rev. Neurosci.
volume
12
issue
3
pages
169 - 182
Web of Science type
Review
Web of Science id
000287474900004
ISSN
1471-0048
DOI
10.1038/nrn2995
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1258928
handle
http://hdl.handle.net/1854/LU-1258928
date created
2011-06-09 15:32:04
date last changed
2011-06-17 14:49:23
@article{1258928,
  abstract     = {The delivery of many potentially therapeutic and diagnostic compounds to specific areas of the brain is restricted by brain barriers, of which the most well known are the blood-brain barrier (BBB) and the blood-cerebrospinal fluid (CSF) barrier. Recent studies have shown numerous additional roles of these barriers, including an involvement in neurodevelopment, in the control of cerebral blood flow, and-when barrier integrity is impaired-in the pathology of many common CNS disorders such as Alzheimer's disease, Parkinson's disease and stroke.},
  author       = {Neuwelt, Edward A and Bauer, Bj{\"o}rn  and Fahlke, Christoph  and Fricker, Gert  and Iadecola, Constantino  and Janigro, Damir  and Leybaert, Luc and Molnar, Zoltan  and O{\textquoteright}Donnell, Martha  and Povlishock, John  and Saunders, Norman  and Sharp, Frank  and Stanimirovic, Danica  and Watts, Ryan  and Drewes, Lester },
  issn         = {1471-0048},
  journal      = {NATURE REVIEWS NEUROSCIENCE},
  keyword      = {MULTIPLE-SCLEROSIS,INDUCED UP-REGULATION,CENTRAL-NERVOUS-SYSTEM,NECROSIS-FACTOR-ALPHA,AMINO-ACID TRANSPORTERS,HEREDITARY CEREBRAL-HEMORRHAGE,GREEN FLUORESCENT PROTEIN,BINDING CASSETTE TRANSPORTERS,P-GLYCOPROTEIN EXPRESSION,HUMAN BLOOD-BRAIN},
  language     = {eng},
  number       = {3},
  pages        = {169--182},
  title        = {Engaging neuroscience to advance translational research in brain barrier biology},
  url          = {http://dx.doi.org/10.1038/nrn2995},
  volume       = {12},
  year         = {2011},
}

Chicago
Neuwelt, Edward A, Björn Bauer, Christoph Fahlke, Gert Fricker, Constantino Iadecola, Damir Janigro, Luc Leybaert, et al. 2011. “Engaging Neuroscience to Advance Translational Research in Brain Barrier Biology.” Nature Reviews Neuroscience 12 (3): 169–182.
APA
Neuwelt, E. A., Bauer, B., Fahlke, C., Fricker, G., Iadecola, C., Janigro, D., Leybaert, L., et al. (2011). Engaging neuroscience to advance translational research in brain barrier biology. NATURE REVIEWS NEUROSCIENCE, 12(3), 169–182.
Vancouver
1.
Neuwelt EA, Bauer B, Fahlke C, Fricker G, Iadecola C, Janigro D, et al. Engaging neuroscience to advance translational research in brain barrier biology. NATURE REVIEWS NEUROSCIENCE. 2011;12(3):169–82.
MLA
Neuwelt, Edward A, Björn Bauer, Christoph Fahlke, et al. “Engaging Neuroscience to Advance Translational Research in Brain Barrier Biology.” NATURE REVIEWS NEUROSCIENCE 12.3 (2011): 169–182. Print.