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First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia

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Abstract
The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed.
Keywords
KDR MUTATION, INSECTICIDE RESISTANCE, SODIUM-CHANNEL GENE, GAMBIAE COMPLEX, PYRETHROID INSECTICIDES, BURKINA-FASO, TREATED NETS, COTE-DIVOIRE, POPULATIONS, MALARIA

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Citation

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MLA
Gebre, Delenasaw Yewhalaw et al. “First Evidence of High Knockdown Resistance Frequency in Anopheles Arabiensis (diptera: Culicidae) from Ethiopia.” AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 83.1 (2010): 122–125. Print.
APA
Gebre, D. Y., Van Bortel, W., Denis, L., Coosemans, M., Duchateau, L., & Speybroeck, N. (2010). First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 83(1), 122–125.
Chicago author-date
Gebre, Delenasaw Yewhalaw, Wim Van Bortel, Leen Denis, Marc Coosemans, Luc Duchateau, and Niko Speybroeck. 2010. “First Evidence of High Knockdown Resistance Frequency in Anopheles Arabiensis (diptera: Culicidae) from Ethiopia.” American Journal of Tropical Medicine and Hygiene 83 (1): 122–125.
Chicago author-date (all authors)
Gebre, Delenasaw Yewhalaw, Wim Van Bortel, Leen Denis, Marc Coosemans, Luc Duchateau, and Niko Speybroeck. 2010. “First Evidence of High Knockdown Resistance Frequency in Anopheles Arabiensis (diptera: Culicidae) from Ethiopia.” American Journal of Tropical Medicine and Hygiene 83 (1): 122–125.
Vancouver
1.
Gebre DY, Van Bortel W, Denis L, Coosemans M, Duchateau L, Speybroeck N. First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2010;83(1):122–5.
IEEE
[1]
D. Y. Gebre, W. Van Bortel, L. Denis, M. Coosemans, L. Duchateau, and N. Speybroeck, “First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia,” AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, vol. 83, no. 1, pp. 122–125, 2010.
@article{1235172,
  abstract     = {The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed.},
  author       = {Gebre, Delenasaw Yewhalaw and Van Bortel, Wim and Denis, Leen and Coosemans, Marc and Duchateau, Luc and Speybroeck, Niko},
  issn         = {0002-9637},
  journal      = {AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE},
  keywords     = {KDR MUTATION,INSECTICIDE RESISTANCE,SODIUM-CHANNEL GENE,GAMBIAE COMPLEX,PYRETHROID INSECTICIDES,BURKINA-FASO,TREATED NETS,COTE-DIVOIRE,POPULATIONS,MALARIA},
  language     = {eng},
  number       = {1},
  pages        = {122--125},
  title        = {First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia},
  url          = {http://dx.doi.org/10.4269/ajtmh.2010.09-0738},
  volume       = {83},
  year         = {2010},
}

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