First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia
- Author
- Delenasaw Yewhalaw Gebre, Wim Van Bortel, Leen Denis, Marc Coosemans, Luc Duchateau (UGent) and Niko Speybroeck
- Organization
- Abstract
- The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed.
- Keywords
- KDR MUTATION, INSECTICIDE RESISTANCE, SODIUM-CHANNEL GENE, GAMBIAE COMPLEX, PYRETHROID INSECTICIDES, BURKINA-FASO, TREATED NETS, COTE-DIVOIRE, POPULATIONS, MALARIA
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-1235172
- MLA
- Gebre, Delenasaw Yewhalaw, et al. “First Evidence of High Knockdown Resistance Frequency in Anopheles Arabiensis (Diptera: Culicidae) from Ethiopia.” AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, vol. 83, no. 1, 2010, pp. 122–25, doi:10.4269/ajtmh.2010.09-0738.
- APA
- Gebre, D. Y., Van Bortel, W., Denis, L., Coosemans, M., Duchateau, L., & Speybroeck, N. (2010). First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 83(1), 122–125. https://doi.org/10.4269/ajtmh.2010.09-0738
- Chicago author-date
- Gebre, Delenasaw Yewhalaw, Wim Van Bortel, Leen Denis, Marc Coosemans, Luc Duchateau, and Niko Speybroeck. 2010. “First Evidence of High Knockdown Resistance Frequency in Anopheles Arabiensis (Diptera: Culicidae) from Ethiopia.” AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 83 (1): 122–25. https://doi.org/10.4269/ajtmh.2010.09-0738.
- Chicago author-date (all authors)
- Gebre, Delenasaw Yewhalaw, Wim Van Bortel, Leen Denis, Marc Coosemans, Luc Duchateau, and Niko Speybroeck. 2010. “First Evidence of High Knockdown Resistance Frequency in Anopheles Arabiensis (Diptera: Culicidae) from Ethiopia.” AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 83 (1): 122–125. doi:10.4269/ajtmh.2010.09-0738.
- Vancouver
- 1.Gebre DY, Van Bortel W, Denis L, Coosemans M, Duchateau L, Speybroeck N. First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2010;83(1):122–5.
- IEEE
- [1]D. Y. Gebre, W. Van Bortel, L. Denis, M. Coosemans, L. Duchateau, and N. Speybroeck, “First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia,” AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, vol. 83, no. 1, pp. 122–125, 2010.
@article{1235172, abstract = {{The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed.}}, author = {{Gebre, Delenasaw Yewhalaw and Van Bortel, Wim and Denis, Leen and Coosemans, Marc and Duchateau, Luc and Speybroeck, Niko}}, issn = {{0002-9637}}, journal = {{AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE}}, keywords = {{KDR MUTATION,INSECTICIDE RESISTANCE,SODIUM-CHANNEL GENE,GAMBIAE COMPLEX,PYRETHROID INSECTICIDES,BURKINA-FASO,TREATED NETS,COTE-DIVOIRE,POPULATIONS,MALARIA}}, language = {{eng}}, number = {{1}}, pages = {{122--125}}, title = {{First evidence of high knockdown resistance frequency in anopheles arabiensis (diptera: Culicidae) from Ethiopia}}, url = {{http://doi.org/10.4269/ajtmh.2010.09-0738}}, volume = {{83}}, year = {{2010}}, }
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