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Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores

Matthias D'hooghe UGent, Sara Kenis UGent, Karel Vervisch UGent, Carmen Lategan, Peter Smith, Kelly Chibale and Norbert De Kimpe UGent (2011) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 46(2). p.579-587
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
Aziridinium salts, Aziridines, Ring opening, Triaminopropanes, Antimalarial agents, INTERMEDIATE AZIRIDINIUM SALTS, PLASMODIUM-FALCIPARUM, PURINE DERIVATIVES, CHIRAL AZIRIDINES, 1-ALKYL-2-(BROMOMETHYL)AZIRIDINES, CHEMOTHERAPY, EPOXIDES, POTENT, ASSAY, IONS
journal title
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Eur. J. Med. Chem.
volume
46
issue
2
pages
579 - 587
Web of Science type
Article
Web of Science id
000287617500013
JCR category
CHEMISTRY, MEDICINAL
JCR impact factor
3.346 (2011)
JCR rank
13/57 (2011)
JCR quartile
1 (2011)
ISSN
0223-5234
DOI
10.1016/j.ejmech.2010.11.037
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1234402
handle
http://hdl.handle.net/1854/LU-1234402
date created
2011-05-24 16:06:35
date last changed
2011-05-25 11:46:05
@article{1234402,
  author       = {D'hooghe, Matthias and Kenis, Sara and Vervisch, Karel and Lategan, Carmen and Smith, Peter and Chibale, Kelly and De Kimpe, Norbert},
  issn         = {0223-5234},
  journal      = {EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY},
  keyword      = {Aziridinium salts,Aziridines,Ring opening,Triaminopropanes,Antimalarial agents,INTERMEDIATE AZIRIDINIUM SALTS,PLASMODIUM-FALCIPARUM,PURINE DERIVATIVES,CHIRAL AZIRIDINES,1-ALKYL-2-(BROMOMETHYL)AZIRIDINES,CHEMOTHERAPY,EPOXIDES,POTENT,ASSAY,IONS},
  language     = {eng},
  number       = {2},
  pages        = {579--587},
  title        = {Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores},
  url          = {http://dx.doi.org/10.1016/j.ejmech.2010.11.037},
  volume       = {46},
  year         = {2011},
}

Chicago
D’hooghe, Matthias, Sara Kenis, Karel Vervisch, Carmen Lategan, Peter Smith, Kelly Chibale, and Norbert De Kimpe. 2011. “Synthesis of 2-(aminomethyl)aziridines and Their Microwave-assisted Ring Opening to 1,2,3-triaminopropanes as Novel Antimalarial Pharmacophores.” European Journal of Medicinal Chemistry 46 (2): 579–587.
APA
D’hooghe, M., Kenis, S., Vervisch, K., Lategan, C., Smith, P., Chibale, K., & De Kimpe, N. (2011). Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 46(2), 579–587.
Vancouver
1.
D’hooghe M, Kenis S, Vervisch K, Lategan C, Smith P, Chibale K, et al. Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2011;46(2):579–87.
MLA
D’hooghe, Matthias, Sara Kenis, Karel Vervisch, et al. “Synthesis of 2-(aminomethyl)aziridines and Their Microwave-assisted Ring Opening to 1,2,3-triaminopropanes as Novel Antimalarial Pharmacophores.” EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 46.2 (2011): 579–587. Print.