Advanced search
1 file | 554.85 KB Add to list

The influence of microgravity on invasive growth in Saccharomyces cerevisiae

(2011) ASTROBIOLOGY. 11(1). p.45-55
Author
Organization
Abstract
This study investigates the effects of microgravity on colony growth and the morphological transition from single cells to short invasive filaments in the model eukaryotic organism Saccharomyces cerevisiae. Two-dimensional spreading of the yeast colonies grown on semi-solid agar medium was reduced under microgravity in the Sigma 1278b laboratory strain but not in the CMBSESA1 industrial strain. This was supported by the Sigma 1278b proteome map under microgravity conditions, which revealed upregulation of proteins linked to anaerobic conditions. The Sigma 1278b strain showed a reduced invasive growth in the center of the yeast colony. Bud scar distribution was slightly affected, with a switch toward more random budding. Together, microgravity conditions disturb spatially programmed budding patterns and generate strain-dependent growth differences in yeast colonies on semi-solid medium.
Keywords
INTERNATIONAL-SPACE-STATION, CANDIDA-ALBICANS, GENE-EXPRESSION, Adhesion, Budding, SHEAR MODELED MICROGRAVITY, ESCHERICHIA-COLI, BIOFILM FORMATION, STRESS-RESPONSE, IMMUNE-SYSTEM, CELL-CELL, YEAST, Microgravity, Saccharomyces cerevisiae, Invasive growth, Proteomics

Downloads

  • ast.2010 vanmulders.pdf
    • full text
    • |
    • open access
    • |
    • PDF
    • |
    • 554.85 KB

Citation

Please use this url to cite or link to this publication:

MLA
Van Mulders, Sebastiaan E et al. “The Influence of Microgravity on Invasive Growth in Saccharomyces Cerevisiae.” ASTROBIOLOGY 11.1 (2011): 45–55. Print.
APA
Van Mulders, S. E., Stassen, C., Daenen, L., Devreese, B., Siewers, V., van Eijsden, R. G., Nielsen, J., et al. (2011). The influence of microgravity on invasive growth in Saccharomyces cerevisiae. ASTROBIOLOGY, 11(1), 45–55.
Chicago author-date
Van Mulders, Sebastiaan E, Catherine Stassen, Luk Daenen, Bart Devreese, Verena Siewers, Rudy GE van Eijsden, Jens Nielsen, Freddy R Delvaux, and Ronnie Willaert. 2011. “The Influence of Microgravity on Invasive Growth in Saccharomyces Cerevisiae.” Astrobiology 11 (1): 45–55.
Chicago author-date (all authors)
Van Mulders, Sebastiaan E, Catherine Stassen, Luk Daenen, Bart Devreese, Verena Siewers, Rudy GE van Eijsden, Jens Nielsen, Freddy R Delvaux, and Ronnie Willaert. 2011. “The Influence of Microgravity on Invasive Growth in Saccharomyces Cerevisiae.” Astrobiology 11 (1): 45–55.
Vancouver
1.
Van Mulders SE, Stassen C, Daenen L, Devreese B, Siewers V, van Eijsden RG, et al. The influence of microgravity on invasive growth in Saccharomyces cerevisiae. ASTROBIOLOGY. 2011;11(1):45–55.
IEEE
[1]
S. E. Van Mulders et al., “The influence of microgravity on invasive growth in Saccharomyces cerevisiae,” ASTROBIOLOGY, vol. 11, no. 1, pp. 45–55, 2011.
@article{1231869,
  abstract     = {This study investigates the effects of microgravity on colony growth and the morphological transition from single cells to short invasive filaments in the model eukaryotic organism Saccharomyces cerevisiae. Two-dimensional spreading of the yeast colonies grown on semi-solid agar medium was reduced under microgravity in the Sigma 1278b laboratory strain but not in the CMBSESA1 industrial strain. This was supported by the Sigma 1278b proteome map under microgravity conditions, which revealed upregulation of proteins linked to anaerobic conditions. The Sigma 1278b strain showed a reduced invasive growth in the center of the yeast colony. Bud scar distribution was slightly affected, with a switch toward more random budding. Together, microgravity conditions disturb spatially programmed budding patterns and generate strain-dependent growth differences in yeast colonies on semi-solid medium.},
  author       = {Van Mulders, Sebastiaan E and Stassen, Catherine and Daenen, Luk and Devreese, Bart and Siewers, Verena and van Eijsden, Rudy GE and Nielsen, Jens and Delvaux, Freddy R and Willaert, Ronnie},
  issn         = {1531-1074},
  journal      = {ASTROBIOLOGY},
  keywords     = {INTERNATIONAL-SPACE-STATION,CANDIDA-ALBICANS,GENE-EXPRESSION,Adhesion,Budding,SHEAR MODELED MICROGRAVITY,ESCHERICHIA-COLI,BIOFILM FORMATION,STRESS-RESPONSE,IMMUNE-SYSTEM,CELL-CELL,YEAST,Microgravity,Saccharomyces cerevisiae,Invasive growth,Proteomics},
  language     = {eng},
  number       = {1},
  pages        = {45--55},
  title        = {The influence of microgravity on invasive growth in Saccharomyces cerevisiae},
  url          = {http://dx.doi.org/10.1089/ast.2010.0518},
  volume       = {11},
  year         = {2011},
}

Altmetric
View in Altmetric
Web of Science
Times cited: