Advanced search
1 file | 246.66 KB

Gold(III) chloride catalysed synthesis of 5-alkylidene-dihydrothiazoles

Thomas Heugebaert (UGent) , Leander Vervaecke (UGent) and Christian Stevens (UGent)
(2011) ORGANIC & BIOMOLECULAR CHEMISTRY. 9(13). p.4791-4794
Author
Organization
Abstract
A two-step synthesis of dihydrothiazoles from easily available, cheap starting materials is presented. First, the previously unknown N-propargylic dithiocarboimidates are produced in good yields. The subsequent gold catalysed ring closure is fast and efficient, leading to dihydrothiazoles through a cascade of 5-exo-dig cyclisation and 1,3-alkyl migration.
Keywords
glitazones, 5-exo-dig, thiazoles, thio-Claisen, gold, catalysis, ring closure

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 246.66 KB

Citation

Please use this url to cite or link to this publication:

Chicago
Heugebaert, Thomas, Leander Vervaecke, and Christian Stevens. 2011. “Gold(III) Chloride Catalysed Synthesis of 5-alkylidene-dihydrothiazoles.” Organic & Biomolecular Chemistry 9 (13): 4791–4794.
APA
Heugebaert, T., Vervaecke, L., & Stevens, C. (2011). Gold(III) chloride catalysed synthesis of 5-alkylidene-dihydrothiazoles. ORGANIC & BIOMOLECULAR CHEMISTRY, 9(13), 4791–4794.
Vancouver
1.
Heugebaert T, Vervaecke L, Stevens C. Gold(III) chloride catalysed synthesis of 5-alkylidene-dihydrothiazoles. ORGANIC & BIOMOLECULAR CHEMISTRY. 2011;9(13):4791–4.
MLA
Heugebaert, Thomas, Leander Vervaecke, and Christian Stevens. “Gold(III) Chloride Catalysed Synthesis of 5-alkylidene-dihydrothiazoles.” ORGANIC & BIOMOLECULAR CHEMISTRY 9.13 (2011): 4791–4794. Print.
@article{1231374,
  abstract     = {A two-step synthesis of dihydrothiazoles from easily available, cheap starting materials is presented. First, the previously unknown N-propargylic dithiocarboimidates are produced in good yields. The subsequent gold catalysed ring closure is fast and efficient, leading to dihydrothiazoles through a cascade of 5-exo-dig cyclisation and 1,3-alkyl migration.},
  author       = {Heugebaert, Thomas and Vervaecke, Leander and Stevens, Christian},
  issn         = {1477-0520},
  journal      = {ORGANIC \& BIOMOLECULAR CHEMISTRY},
  keyword      = {glitazones,5-exo-dig,thiazoles,thio-Claisen,gold,catalysis,ring closure},
  language     = {eng},
  number       = {13},
  pages        = {4791--4794},
  title        = {Gold(III) chloride catalysed synthesis of 5-alkylidene-dihydrothiazoles},
  url          = {http://dx.doi.org/10.1039/C1OB05509G},
  volume       = {9},
  year         = {2011},
}

Altmetric
View in Altmetric
Web of Science
Times cited: