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Fluor-19 MRI oximetry: impact of perfluorocarbon blood-tissue partitioning

Steven Baete (UGent) and Yves De Deene (UGent)
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Abstract
The impact of the partitioning of oxygenation markers (perfluorocarbons) between blood and tissue in fluor-19 MRI oximetry is evaluated through computer simulations. The simulation studies the correspondence between actual and fluor-19 MRI measured oxygen tension. Simulation results indicate that the blood-tissue partitioning of perfluorocarbons has a serious impact on the deviations between actual and fluor-19 measured oxygen tensions. In addition, perfluorocarbon presence in blood influences the actual oxygen tension as compared to a situation without perfluorocarbons. Fluor-19 MRI oximetry can be applied to map oxygen concentrations in hypoxic tumor tissues, which are well known to reduce cancer treatment efficacy.

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Chicago
Baete, Steven, and Yves De Deene. 2011. “Fluor-19 MRI Oximetry: Impact of Perfluorocarbon Blood-tissue Partitioning.” In ISMRM Benelux Chapter, 3rd Annual Meeting, Abstracts. International Society for Magnetic Resonance in Medicine (ISMRM). Benelux Chapter.
APA
Baete, S., & De Deene, Y. (2011). Fluor-19 MRI oximetry: impact of perfluorocarbon blood-tissue partitioning. ISMRM Benelux Chapter, 3rd Annual meeting, Abstracts. Presented at the 3rd Annual meeting of the ISMRM Benelux Chapter, International Society for Magnetic Resonance in Medicine (ISMRM). Benelux Chapter.
Vancouver
1.
Baete S, De Deene Y. Fluor-19 MRI oximetry: impact of perfluorocarbon blood-tissue partitioning. ISMRM Benelux Chapter, 3rd Annual meeting, Abstracts. International Society for Magnetic Resonance in Medicine (ISMRM). Benelux Chapter; 2011.
MLA
Baete, Steven, and Yves De Deene. “Fluor-19 MRI Oximetry: Impact of Perfluorocarbon Blood-tissue Partitioning.” ISMRM Benelux Chapter, 3rd Annual Meeting, Abstracts. International Society for Magnetic Resonance in Medicine (ISMRM). Benelux Chapter, 2011. Print.
@inproceedings{1228524,
  abstract     = {The impact of the partitioning of oxygenation markers (perfluorocarbons) between blood and tissue in fluor-19 MRI oximetry is evaluated through computer simulations. The simulation studies the correspondence between actual and fluor-19 MRI measured oxygen tension. Simulation results indicate that the blood-tissue partitioning of perfluorocarbons has a serious impact on the deviations between actual and fluor-19 measured oxygen tensions. In addition, perfluorocarbon presence in blood influences the actual oxygen tension as compared to a situation without perfluorocarbons. Fluor-19 MRI oximetry can be applied to map oxygen concentrations in hypoxic tumor tissues, which are well known to reduce cancer treatment efficacy.},
  author       = {Baete, Steven and De Deene, Yves},
  booktitle    = {ISMRM Benelux Chapter, 3rd Annual meeting, Abstracts},
  language     = {eng},
  location     = {Hoeven, The Netherlands},
  publisher    = {International Society for Magnetic Resonance in Medicine (ISMRM). Benelux Chapter},
  title        = {Fluor-19 MRI oximetry: impact of perfluorocarbon blood-tissue partitioning},
  year         = {2011},
}