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Designing oral vaccines targeting intestinal dendritic cells

Bert Devriendt UGent, Bruno De Geest UGent and Eric Cox UGent (2011) EXPERT OPINION ON DRUG DELIVERY. 8(4). p.467-483
abstract
Areas covered: In this review, current knowledge on dendritic cell subsets is discussed, along with progress in the development of selective antigen targeting to these cells, in addition to focusing on data obtained in mice and, where possible, the pig, as a non-rodent animal model for humans. Moreover, the potential use and benefits of Fc gamma gamma receptor-mediated targeting of antigen delivery systems are highlighted. Expert opinion: In conclusion, dendritic cell targeting ligands grafted on antigen carrier systems should preferably bind to a conserved endocytotic receptor, facilitating the design of a multispecies vaccine platform, which could elicit robust protective immune responses against enteric pathogens.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
FOLLICLE-ASSOCIATED EPITHELIUM, FC-GAMMA RECEPTOR, MUCOSAL IMMUNE-RESPONSES, ANTIGEN-PRESENTING CELLS, MESENTERIC LYMPH-NODES, TRANS-RETINOIC ACID, REGULATORY T-CELLS, C-TYPE LECTIN, IN-VIVO, PEYERS PATCH
journal title
EXPERT OPINION ON DRUG DELIVERY
Expert Opin. Drug Deliv.
volume
8
issue
4
pages
467 - 483
Web of Science type
Review
Web of Science id
000288549600006
JCR category
PHARMACOLOGY & PHARMACY
JCR impact factor
4.896 (2011)
JCR rank
21/259 (2011)
JCR quartile
1 (2011)
ISSN
1742-5247
DOI
10.1517/17425247.2011.561312
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1227231
handle
http://hdl.handle.net/1854/LU-1227231
date created
2011-05-19 10:43:29
date last changed
2011-05-23 11:51:55
@article{1227231,
  abstract     = {Areas covered: In this review, current knowledge on dendritic cell subsets is discussed, along with progress in the development of selective antigen targeting to these cells, in addition to focusing on data obtained in mice and, where possible, the pig, as a non-rodent animal model for humans. Moreover, the potential use and benefits of Fc gamma gamma receptor-mediated targeting of antigen delivery systems are highlighted.
Expert opinion: In conclusion, dendritic cell targeting ligands grafted on antigen carrier systems should preferably bind to a conserved endocytotic receptor, facilitating the design of a multispecies vaccine platform, which could elicit robust protective immune responses against enteric pathogens.},
  author       = {Devriendt, Bert and De Geest, Bruno and Cox, Eric},
  issn         = {1742-5247},
  journal      = {EXPERT OPINION ON DRUG DELIVERY},
  keyword      = {FOLLICLE-ASSOCIATED EPITHELIUM,FC-GAMMA RECEPTOR,MUCOSAL IMMUNE-RESPONSES,ANTIGEN-PRESENTING CELLS,MESENTERIC LYMPH-NODES,TRANS-RETINOIC ACID,REGULATORY T-CELLS,C-TYPE LECTIN,IN-VIVO,PEYERS PATCH},
  language     = {eng},
  number       = {4},
  pages        = {467--483},
  title        = {Designing oral vaccines targeting intestinal dendritic cells},
  url          = {http://dx.doi.org/10.1517/17425247.2011.561312},
  volume       = {8},
  year         = {2011},
}

Chicago
Devriendt, Bert, Bruno De Geest, and Eric Cox. 2011. “Designing Oral Vaccines Targeting Intestinal Dendritic Cells.” Expert Opinion on Drug Delivery 8 (4): 467–483.
APA
Devriendt, B., De Geest, B., & Cox, E. (2011). Designing oral vaccines targeting intestinal dendritic cells. EXPERT OPINION ON DRUG DELIVERY, 8(4), 467–483.
Vancouver
1.
Devriendt B, De Geest B, Cox E. Designing oral vaccines targeting intestinal dendritic cells. EXPERT OPINION ON DRUG DELIVERY. 2011;8(4):467–83.
MLA
Devriendt, Bert, Bruno De Geest, and Eric Cox. “Designing Oral Vaccines Targeting Intestinal Dendritic Cells.” EXPERT OPINION ON DRUG DELIVERY 8.4 (2011): 467–483. Print.