Ghent University Academic Bibliography

Advanced

Enclosed volume determination of concentrated dioctadecyldimethylammonium chloride (DODAC) vesicular dispersions by low-resolution proton NMR diffusometry and T-2 relaxometry

Paolo Sabatino UGent, Pieter Saveyn UGent, José Martins UGent and Paul Van Der Meeren UGent (2011) LANGMUIR. 27(8). p.4532-4540
abstract
The enclosed volume of concentrated dioctadecyldimethylammonium chloride (DODAC) dispersions has been determined by means of low-resolution NMR pfg-diffusometry and T-2 relaxometry. The pfg-NMR diffusometry method is based on the different diffusion behaviors of water in the external and internal phases and as such does not require the addition of a tracer. On the other hand, T-2 relaxometry is based on the different relaxation behaviors of water fractions upon addition of manganese chloride as external (paramagnetic) probe. It was noticed that reliable results are found only for temperatures below the phase transition temperature of DODAC, when the exchange between the two water compartments can be neglected. At 5 degrees C, these two independent methods resulted in similar enclosed volume values, meaning that the results are reliable and reflect the real enclosed volume. In addition, the T-2 relaxometry method has been proven to be useful in the investigation of the DODAC membrane permeability.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
SURFACTANTS, RELAXATION, EFFICIENCIES, LIPOSOMES, VESICLES, INTEGRAL-EQUATIONS, DIFFUSION, INTERNAL VOLUMES, RESONANCE, TRANSPORT
journal title
LANGMUIR
Langmuir
volume
27
issue
8
pages
4532 - 4540
Web of Science type
Article
Web of Science id
000289321000036
JCR category
MATERIALS SCIENCE, MULTIDISCIPLINARY
JCR impact factor
4.186 (2011)
JCR rank
30/229 (2011)
JCR quartile
1 (2011)
ISSN
0743-7463
DOI
10.1021/la200327y
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1221232
handle
http://hdl.handle.net/1854/LU-1221232
date created
2011-05-11 11:24:27
date last changed
2011-06-08 10:18:06
@article{1221232,
  abstract     = {The enclosed volume of concentrated dioctadecyldimethylammonium chloride (DODAC) dispersions has been determined by means of low-resolution NMR pfg-diffusometry and T-2 relaxometry. The pfg-NMR diffusometry method is based on the different diffusion behaviors of water in the external and internal phases and as such does not require the addition of a tracer. On the other hand, T-2 relaxometry is based on the different relaxation behaviors of water fractions upon addition of manganese chloride as external (paramagnetic) probe. It was noticed that reliable results are found only for temperatures below the phase transition temperature of DODAC, when the exchange between the two water compartments can be neglected. At 5 degrees C, these two independent methods resulted in similar enclosed volume values, meaning that the results are reliable and reflect the real enclosed volume. In addition, the T-2 relaxometry method has been proven to be useful in the investigation of the DODAC membrane permeability.},
  author       = {Sabatino, Paolo and Saveyn, Pieter and Martins, Jos{\'e} and Van Der Meeren, Paul},
  issn         = {0743-7463},
  journal      = {LANGMUIR},
  keyword      = {SURFACTANTS,RELAXATION,EFFICIENCIES,LIPOSOMES,VESICLES,INTEGRAL-EQUATIONS,DIFFUSION,INTERNAL VOLUMES,RESONANCE,TRANSPORT},
  language     = {eng},
  number       = {8},
  pages        = {4532--4540},
  title        = {Enclosed volume determination of concentrated dioctadecyldimethylammonium chloride (DODAC) vesicular dispersions by low-resolution proton NMR diffusometry and T-2 relaxometry},
  url          = {http://dx.doi.org/10.1021/la200327y},
  volume       = {27},
  year         = {2011},
}

Chicago
Sabatino, Paolo, Pieter Saveyn, José Martins, and Paul Van Der Meeren. 2011. “Enclosed Volume Determination of Concentrated Dioctadecyldimethylammonium Chloride (DODAC) Vesicular Dispersions by Low-resolution Proton NMR Diffusometry and T-2 Relaxometry.” Langmuir 27 (8): 4532–4540.
APA
Sabatino, P., Saveyn, P., Martins, J., & Van Der Meeren, P. (2011). Enclosed volume determination of concentrated dioctadecyldimethylammonium chloride (DODAC) vesicular dispersions by low-resolution proton NMR diffusometry and T-2 relaxometry. LANGMUIR, 27(8), 4532–4540.
Vancouver
1.
Sabatino P, Saveyn P, Martins J, Van Der Meeren P. Enclosed volume determination of concentrated dioctadecyldimethylammonium chloride (DODAC) vesicular dispersions by low-resolution proton NMR diffusometry and T-2 relaxometry. LANGMUIR. 2011;27(8):4532–40.
MLA
Sabatino, Paolo, Pieter Saveyn, José Martins, et al. “Enclosed Volume Determination of Concentrated Dioctadecyldimethylammonium Chloride (DODAC) Vesicular Dispersions by Low-resolution Proton NMR Diffusometry and T-2 Relaxometry.” LANGMUIR 27.8 (2011): 4532–4540. Print.