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Fabrication of an implantable stretchable electro-osmosis pump

Amir Jahanshahi (UGent) , Fabrice Axisa (UGent) and Jan Vanfleteren (UGent)
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Abstract
The aim of this paper is to demonstrate the feasibility of an implantable, low voltage driven microfluidic pump to deliver drugs. The micro pump has a high degree of biocompatibility and mechanical deformation capability, thanks to the use of elastic silicone elastomers (PDMS) for integration and embedding of the pump. We are using the new method of transverse DC electro-osmosis, which is demonstrated already in the literature. The method uses the fabrication of periodic grooves on top of the micro channel and the application of a DC voltage across the channel. In this contribution, for the first time the production and operation of soft elastic versions of such a pump, compatible with body tissue, is demonstrated. For the interconnects, gold is selectively electro-deposited on Cu-foil and is transferred to PDMS layer. Having only gold as the interconnect ascertains the high degree of bio-compatibility of the device. This pump works with voltages about 10V and produces mean flow speeds of about 60μm/s. The flow has also a helical profile which is a very good advantage to use this pump as a mixer for micro fluidic applications. Flow rate is measured by introducing dyed micro particles along with the liquid inside the channel.
Keywords
Micro Pump, Electro-osmosis, PDMS, Microfluidics

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Chicago
Jahanshahi, Amir, Fabrice Axisa, and Jan Vanfleteren. 2011. “Fabrication of an Implantable Stretchable Electro-osmosis Pump.” In Proceedings of Spie, the International Society for Optical Engineering, ed. Holger Becker and Bonnie L Gray. Vol. 7929. Bellingham, WA, USA: SPIE.
APA
Jahanshahi, A., Axisa, F., & Vanfleteren, J. (2011). Fabrication of an implantable stretchable electro-osmosis pump. In H. Becker & B. L. Gray (Eds.), PROCEEDINGS OF SPIE, THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING (Vol. 7929). Presented at the Conference on Microfluidics, BioMEMS, and Medical Microsystems IX, Bellingham, WA, USA: SPIE.
Vancouver
1.
Jahanshahi A, Axisa F, Vanfleteren J. Fabrication of an implantable stretchable electro-osmosis pump. In: Becker H, Gray BL, editors. PROCEEDINGS OF SPIE, THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. Bellingham, WA, USA: SPIE; 2011.
MLA
Jahanshahi, Amir, Fabrice Axisa, and Jan Vanfleteren. “Fabrication of an Implantable Stretchable Electro-osmosis Pump.” Proceedings of Spie, the International Society for Optical Engineering. Ed. Holger Becker & Bonnie L Gray. Vol. 7929. Bellingham, WA, USA: SPIE, 2011. Print.
@inproceedings{1215866,
  abstract     = {The aim of this paper is to demonstrate the feasibility of an implantable, low voltage driven micro\unmatched{fb02}uidic pump to deliver drugs. The micro pump has a high degree of biocompatibility and mechanical deformation capability, thanks to the use of elastic silicone elastomers (PDMS) for integration and embedding of the pump. We are using the new method of transverse DC electro-osmosis, which is demonstrated already in the literature. The method uses the fabrication of periodic grooves on top of the micro channel and the application of a DC voltage across the channel. In this contribution, for the \unmatched{fb01}rst time the production and operation of soft elastic versions of such a pump, compatible with body tissue, is demonstrated. For the interconnects, gold is selectively electro-deposited on Cu-foil and is transferred to PDMS layer. Having only gold as the interconnect ascertains the high degree of bio-compatibility of the device. This pump works with voltages about 10V and produces mean \unmatched{fb02}ow speeds of about 60\ensuremath{\mu}m/s. The \unmatched{fb02}ow has also a helical pro\unmatched{fb01}le which is a very good advantage to use this pump as a mixer for micro \unmatched{fb02}uidic applications. Flow rate is measured by introducing dyed micro particles along with the liquid inside the channel.},
  articleno    = {79290R},
  author       = {Jahanshahi, Amir and Axisa, Fabrice and Vanfleteren, Jan},
  booktitle    = {PROCEEDINGS OF SPIE, THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING},
  editor       = {Becker, Holger and Gray, Bonnie L},
  isbn         = {9780819484666},
  issn         = {0277-786X},
  keyword      = {Micro Pump,Electro-osmosis,PDMS,Microfluidics},
  language     = {eng},
  location     = {San Francisco, CA, USA},
  pages        = {8},
  publisher    = {SPIE},
  title        = {Fabrication of an implantable stretchable electro-osmosis pump},
  url          = {http://dx.doi.org/10.1117/12.873812},
  volume       = {7929},
  year         = {2011},
}

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