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Fabrication of an implantable stretchable electro-osmosis pump

Amir Jahanshahi UGent, Fabrice Axisa UGent and Jan Vanfleteren UGent (2011) PROCEEDINGS OF SPIE, THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. 7929.
abstract
The aim of this paper is to demonstrate the feasibility of an implantable, low voltage driven microfluidic pump to deliver drugs. The micro pump has a high degree of biocompatibility and mechanical deformation capability, thanks to the use of elastic silicone elastomers (PDMS) for integration and embedding of the pump. We are using the new method of transverse DC electro-osmosis, which is demonstrated already in the literature. The method uses the fabrication of periodic grooves on top of the micro channel and the application of a DC voltage across the channel. In this contribution, for the first time the production and operation of soft elastic versions of such a pump, compatible with body tissue, is demonstrated. For the interconnects, gold is selectively electro-deposited on Cu-foil and is transferred to PDMS layer. Having only gold as the interconnect ascertains the high degree of bio-compatibility of the device. This pump works with voltages about 10V and produces mean flow speeds of about 60μm/s. The flow has also a helical profile which is a very good advantage to use this pump as a mixer for micro fluidic applications. Flow rate is measured by introducing dyed micro particles along with the liquid inside the channel.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
keyword
Micro Pump, Electro-osmosis, PDMS, Microfluidics
in
PROCEEDINGS OF SPIE, THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING
Proc. SPIE Int. Soc. Opt. Eng.
editor
Holger Becker and Bonnie L Gray
volume
7929
issue title
Microfluidics, BioMEMS, and medical microsystems IX
article_number
79290R
pages
8 pages
publisher
SPIE
place of publication
Bellingham, WA, USA
conference name
Conference on Microfluidics, BioMEMS, and Medical Microsystems IX
conference location
San Francisco, CA, USA
conference start
2011-01-23
conference end
2011-01-25
Web of Science type
Proceedings Paper
Web of Science id
000298046300023
ISSN
0277-786X
ISBN
9780819484666
DOI
10.1117/12.873812
language
English
UGent publication?
yes
classification
P1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1215866
handle
http://hdl.handle.net/1854/LU-1215866
date created
2011-05-02 16:16:35
date last changed
2012-04-23 16:13:40
@inproceedings{1215866,
  abstract     = {The aim of this paper is to demonstrate the feasibility of an implantable, low voltage driven micro\unmatched{fb02}uidic pump to deliver drugs. The micro pump has a high degree of biocompatibility and mechanical deformation capability, thanks to the use of elastic silicone elastomers (PDMS) for integration and embedding of the pump. We are using the new method of transverse DC electro-osmosis, which is demonstrated already in the literature. The method uses the fabrication of periodic grooves on top of the micro channel and the application of a DC voltage across the channel. In this contribution, for the \unmatched{fb01}rst time the production and operation of soft elastic versions of such a pump, compatible with body tissue, is demonstrated. For the interconnects, gold is selectively electro-deposited on Cu-foil and is transferred to PDMS layer. Having only gold as the interconnect ascertains the high degree of bio-compatibility of the device. This pump works with voltages about 10V and produces mean \unmatched{fb02}ow speeds of about 60\ensuremath{\mu}m/s. The \unmatched{fb02}ow has also a helical pro\unmatched{fb01}le which is a very good advantage to use this pump as a mixer for micro \unmatched{fb02}uidic applications. Flow rate is measured by introducing dyed micro particles along with the liquid inside the channel.},
  articleno    = {79290R},
  author       = {Jahanshahi, Amir and Axisa, Fabrice and Vanfleteren, Jan},
  booktitle    = {PROCEEDINGS OF SPIE, THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING},
  editor       = {Becker, Holger and Gray, Bonnie L},
  isbn         = {9780819484666},
  issn         = {0277-786X},
  keyword      = {Micro Pump,Electro-osmosis,PDMS,Microfluidics},
  language     = {eng},
  location     = {San Francisco, CA, USA},
  pages        = {8},
  publisher    = {SPIE},
  title        = {Fabrication of an implantable stretchable electro-osmosis pump},
  url          = {http://dx.doi.org/10.1117/12.873812},
  volume       = {7929},
  year         = {2011},
}

Chicago
Jahanshahi, Amir, Fabrice Axisa, and Jan Vanfleteren. 2011. “Fabrication of an Implantable Stretchable Electro-osmosis Pump.” In Proceedings of Spie, the International Society for Optical Engineering, ed. Holger Becker and Bonnie L Gray. Vol. 7929. Bellingham, WA, USA: SPIE.
APA
Jahanshahi, A., Axisa, F., & Vanfleteren, J. (2011). Fabrication of an implantable stretchable electro-osmosis pump. In H. Becker & B. L. Gray (Eds.), PROCEEDINGS OF SPIE, THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING (Vol. 7929). Presented at the Conference on Microfluidics, BioMEMS, and Medical Microsystems IX, Bellingham, WA, USA: SPIE.
Vancouver
1.
Jahanshahi A, Axisa F, Vanfleteren J. Fabrication of an implantable stretchable electro-osmosis pump. In: Becker H, Gray BL, editors. PROCEEDINGS OF SPIE, THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. Bellingham, WA, USA: SPIE; 2011.
MLA
Jahanshahi, Amir, Fabrice Axisa, and Jan Vanfleteren. “Fabrication of an Implantable Stretchable Electro-osmosis Pump.” Proceedings of Spie, the International Society for Optical Engineering. Ed. Holger Becker & Bonnie L Gray. Vol. 7929. Bellingham, WA, USA: SPIE, 2011. Print.