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Light-mediated polarization of the PIN3 auxin transporter for the phototropic response in Arabidopsis

Zhaojun Ding UGent, Carlos S Galvan-Ampudia, Emilie Demarsy, Lukasz Langowski UGent, Jürgen Kleine-Vehn UGent, Yuanwei Fan, Miyo T Morita, Masao Tasaka, Christian Fankhauser and Remko Offringa, et al. (2011) NATURE CELL BIOLOGY. 13(4). p.447-452
abstract
Phototropism is an adaptation response, through which plants grow towards the light(1). It involves light perception and asymmetric distribution of the plant hormone auxin(2-12). Here we identify a crucial part of the mechanism for phototropism, revealing how light perception initiates auxin redistribution that leads to directional growth. We show that light polarizes the cellular localization of the auxin efflux carrier PIN3 in hypocotyl endodermis cells, resulting in changes in auxin distribution and differential growth. In the dark, high expression and activity of the PINOID (PID) kinase correlates with a polar targeting of PIN3 to all cell sides. Following illumination, light represses PINOID transcription and PIN3 ispolarized specifically to the inner cell sides by GNOM ARF GTPase GEF (guanine nucleotide exchange factor)-dependent trafficking. Thus, differential trafficking at the shaded and illuminated hypocotyl side aligns PIN3 polarity with the light direction, and presumably redirects auxin flow towards the shaded side, where auxin promotes growth, causing hypocotyls to bend towards the light. Our results imply that PID phosphorylation-dependent recruitment of PIN proteins into distinct trafficking pathways is a mechanism to polarize auxin fluxes in response to different environmental and endogenous cues
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
CARRIERS, GNOM, THALIANA, GROWTH, PROTEIN, GRADIENTS, EFFLUX, BLUE-LIGHT, ROOT GRAVITROPISM, LATERAL TRANSPORT
journal title
NATURE CELL BIOLOGY
Nat. Cell Biol.
volume
13
issue
4
pages
447 - 452
Web of Science type
Article
Web of Science id
000289070900016
JCR category
CELL BIOLOGY
JCR impact factor
19.488 (2011)
JCR rank
6/178 (2011)
JCR quartile
1 (2011)
ISSN
1465-7392
DOI
10.1038/ncb2208
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1213376
handle
http://hdl.handle.net/1854/LU-1213376
date created
2011-04-27 18:26:09
date last changed
2011-05-02 16:30:20
@article{1213376,
  abstract     = {Phototropism is an adaptation response, through which plants grow towards the light(1). It involves light perception and asymmetric distribution of the plant hormone auxin(2-12). Here we identify a crucial part of the mechanism for phototropism, revealing how light perception initiates auxin redistribution that leads to directional growth. We show that light polarizes the cellular localization of the auxin efflux carrier PIN3 in hypocotyl endodermis cells, resulting in changes in auxin distribution and differential growth. In the dark, high expression and activity of the PINOID (PID) kinase correlates with a polar targeting of PIN3 to all cell sides. Following illumination, light represses PINOID transcription and PIN3 ispolarized specifically to the inner cell sides by GNOM ARF GTPase GEF (guanine nucleotide exchange factor)-dependent trafficking. Thus, differential trafficking at the shaded and illuminated hypocotyl side aligns PIN3 polarity with the light direction, and presumably redirects auxin flow towards the shaded side, where auxin promotes growth, causing hypocotyls to bend towards the light. Our results imply that PID phosphorylation-dependent recruitment of PIN proteins into distinct trafficking pathways is a mechanism to polarize auxin fluxes in response to different environmental and endogenous cues},
  author       = {Ding, Zhaojun and Galvan-Ampudia, Carlos S and Demarsy, Emilie and Langowski, Lukasz and Kleine-Vehn, J{\"u}rgen and Fan, Yuanwei and Morita, Miyo T and Tasaka, Masao and Fankhauser, Christian and Offringa, Remko and Friml, Jiri},
  issn         = {1465-7392},
  journal      = {NATURE CELL BIOLOGY},
  keyword      = {CARRIERS,GNOM,THALIANA,GROWTH,PROTEIN,GRADIENTS,EFFLUX,BLUE-LIGHT,ROOT GRAVITROPISM,LATERAL TRANSPORT},
  language     = {eng},
  number       = {4},
  pages        = {447--452},
  title        = {Light-mediated polarization of the PIN3 auxin transporter for the phototropic response in Arabidopsis},
  url          = {http://dx.doi.org/10.1038/ncb2208},
  volume       = {13},
  year         = {2011},
}

Chicago
Ding, Zhaojun, Carlos S Galvan-Ampudia, Emilie Demarsy, Lukasz Langowski, Jürgen Kleine-Vehn, Yuanwei Fan, Miyo T Morita, et al. 2011. “Light-mediated Polarization of the PIN3 Auxin Transporter for the Phototropic Response in Arabidopsis.” Nature Cell Biology 13 (4): 447–452.
APA
Ding, Z., Galvan-Ampudia, C. S., Demarsy, E., Langowski, L., Kleine-Vehn, J., Fan, Y., Morita, M. T., et al. (2011). Light-mediated polarization of the PIN3 auxin transporter for the phototropic response in Arabidopsis. NATURE CELL BIOLOGY, 13(4), 447–452.
Vancouver
1.
Ding Z, Galvan-Ampudia CS, Demarsy E, Langowski L, Kleine-Vehn J, Fan Y, et al. Light-mediated polarization of the PIN3 auxin transporter for the phototropic response in Arabidopsis. NATURE CELL BIOLOGY. 2011;13(4):447–52.
MLA
Ding, Zhaojun, Carlos S Galvan-Ampudia, Emilie Demarsy, et al. “Light-mediated Polarization of the PIN3 Auxin Transporter for the Phototropic Response in Arabidopsis.” NATURE CELL BIOLOGY 13.4 (2011): 447–452. Print.