Lentiviral nuclear import: a complex interplay between virus and host
(2007) BIOESSAYS. 29(5). p.441-451- abstract
- Although the capacity to infect non-dividing cells is a hallmark of lentiviruses, nuclear import is still barely understood. More than 100 research papers have been dedicated to this topic during the last 15 years, yet, more questions have been raised than answers. The signal-facilitating translocation of the viral preintegration complex (PIC) through the nuclear pore complex (NPC) remains unknown. It is clear, however, that nuclear import is the result of a complex interplay between viral and cellular components. In this review, we discuss the current knowledge on nuclear import. We focus on the controversies and pitfalls and discuss the interplay between virus and host.
Please use this url to cite or link to this publication:
http://hdl.handle.net/1854/LU-1206438
- author
- Jan De rijck UGent, Linos Vandekerckhove UGent, Frauke Christ and Zeger Debyser
- organization
- year
- 2007
- type
- journalArticle (review)
- publication status
- published
- subject
- keyword
- TYPE-1 PREINTEGRATION COMPLEXES, CELL-CYCLE ARREST, INTEGRASE INTERACTOR LEDGF/P75, CENTRAL POLYPURINE TRACT, MURINE LEUKEMIA-VIRUS, PLUS-STRAND SYNTHESIS, HIV-1 MATRIX PROTEIN, AVIAN-SARCOMA VIRUS, CENTRAL DNA FLAP, HUMAN-IMMUNODEFICIENCY-VIRUS
- journal title
- BIOESSAYS
- Bioessays
- volume
- 29
- issue
- 5
- pages
- 441 - 451
- Web of Science type
- Review
- Web of Science id
- 000246034700007
- JCR category
- BIOLOGY
- JCR impact factor
- 5.402 (2007)
- JCR rank
- 5/70 (2007)
- JCR quartile
- 1 (2007)
- ISSN
- 0265-9247
- DOI
- 10.1002/bies.20561
- language
- English
- UGent publication?
- yes
- classification
- A1
- copyright statement
- I have transferred the copyright for this publication to the publisher
- id
- 1206438
- handle
- http://hdl.handle.net/1854/LU-1206438
- date created
- 2011-04-11 15:03:38
- date last changed
- 2011-05-10 15:18:21
@article{1206438,
abstract = {Although the capacity to infect non-dividing cells is a hallmark of lentiviruses, nuclear import is still barely understood. More than 100 research papers have been dedicated to this topic during the last 15 years, yet, more questions have been raised than answers. The signal-facilitating translocation of the viral preintegration complex (PIC) through the nuclear pore complex (NPC) remains unknown. It is clear, however, that nuclear import is the result of a complex interplay between viral and cellular components. In this review, we discuss the current knowledge on nuclear import. We focus on the controversies and pitfalls and discuss the interplay between virus and host.},
author = {De rijck, Jan and Vandekerckhove, Linos and Christ, Frauke and Debyser, Zeger},
issn = {0265-9247},
journal = {BIOESSAYS},
keyword = {TYPE-1 PREINTEGRATION COMPLEXES,CELL-CYCLE ARREST,INTEGRASE INTERACTOR LEDGF/P75,CENTRAL POLYPURINE TRACT,MURINE LEUKEMIA-VIRUS,PLUS-STRAND SYNTHESIS,HIV-1 MATRIX PROTEIN,AVIAN-SARCOMA VIRUS,CENTRAL DNA FLAP,HUMAN-IMMUNODEFICIENCY-VIRUS},
language = {eng},
number = {5},
pages = {441--451},
title = {Lentiviral nuclear import: a complex interplay between virus and host},
url = {http://dx.doi.org/10.1002/bies.20561},
volume = {29},
year = {2007},
}
- Chicago
- De rijckJan, Linos Vandekerckhove, Frauke Christ, and Zeger Debyser. 2007. “Lentiviral Nuclear Import: a Complex Interplay Between Virus and Host.” Bioessays 29 (5): 441–451.
- APA
- De rijckJan, Vandekerckhove, L., Christ, F., & Debyser, Z. (2007). Lentiviral nuclear import: a complex interplay between virus and host. BIOESSAYS, 29(5), 441–451.
- Vancouver
- 1.De rijckJan, Vandekerckhove L, Christ F, Debyser Z. Lentiviral nuclear import: a complex interplay between virus and host. BIOESSAYS. 2007;29(5):441–51.
- MLA
- De rijckJan, Linos Vandekerckhove, Frauke Christ, et al. “Lentiviral Nuclear Import: a Complex Interplay Between Virus and Host.” BIOESSAYS 29.5 (2007): 441–451. Print.