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Invasive infection with Rhodococcus equi : two case reports and review of literature

VINCIANE GUYSSENS (UGent) , Linos Vandekerckhove (UGent) , Isabelle Colle (UGent) , P De Rudder, Stijn Blot (UGent) and Dirk Vogelaers (UGent)
(2010) ACTA CLINICA BELGICA. 65(4). p.271-275
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Abstract
Rhodococcus equi infection is rare in humans, but has increasingly been reported in the last three decades, particularly in immunocompromised patients. The infection is mainly pulmonary but can also assume an extra-pulmonary form. R. equi infection is difficult to diagnose at an early stage both from a clinical and microbiologic view. Only correct and timely diagnosis and treatment can help reduce significant morbidity and mortality. Optimal treatment probably consists of prolonged, preferably triple combination therapy, including vancomycin, with optimization of pharmacokinetic parameters and screening for drug interactions, when indicated. Two clinical cases of invasive R. equi infection are reported in this manuscript: a pulmonary form and an extra-pulmonary form with brain abscesses, both in immunocompromised patients, with detailed description of symptoms, analysis, treatment, and outcome.
Keywords
Rhodococcus equi, IMMUNOCOMPETENT PATIENT, pulmonary infection, extra-pulmonary infection, BRAIN-ABSCESS, PATHOGEN

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Chicago
GUYSSENS, VINCIANE, Linos Vandekerckhove, Isabelle Colle, P De Rudder, Stijn Blot, and Dirk Vogelaers. 2010. “Invasive Infection with Rhodococcus Equi : Two Case Reports and Review of Literature.” Acta Clinica Belgica 65 (4): 271–275.
APA
GUYSSENS, V., Vandekerckhove, L., Colle, I., De Rudder, P., Blot, S., & Vogelaers, D. (2010). Invasive infection with Rhodococcus equi : two case reports and review of literature. ACTA CLINICA BELGICA, 65(4), 271–275.
Vancouver
1.
GUYSSENS V, Vandekerckhove L, Colle I, De Rudder P, Blot S, Vogelaers D. Invasive infection with Rhodococcus equi : two case reports and review of literature. ACTA CLINICA BELGICA. 2010;65(4):271–5.
MLA
GUYSSENS, VINCIANE, Linos Vandekerckhove, Isabelle Colle, et al. “Invasive Infection with Rhodococcus Equi : Two Case Reports and Review of Literature.” ACTA CLINICA BELGICA 65.4 (2010): 271–275. Print.
@article{1206255,
  abstract     = {Rhodococcus equi infection is rare in humans, but has increasingly been reported in the last three decades, particularly in immunocompromised patients. The infection is mainly pulmonary but can also assume an extra-pulmonary form. R. equi infection is difficult to diagnose at an early stage both from a clinical and microbiologic view. Only correct and timely diagnosis and treatment can help reduce significant morbidity and mortality. Optimal treatment probably consists of prolonged, preferably triple combination therapy, including vancomycin, with optimization of pharmacokinetic parameters and screening for drug interactions, when indicated. Two clinical cases of invasive R. equi infection are reported in this manuscript: a pulmonary form and an extra-pulmonary form with brain abscesses, both in immunocompromised patients, with detailed description of symptoms, analysis, treatment, and outcome.},
  author       = {GUYSSENS, VINCIANE and Vandekerckhove, Linos and Colle, Isabelle and De Rudder, P and Blot, Stijn and Vogelaers, Dirk},
  issn         = {0001-5512},
  journal      = {ACTA CLINICA BELGICA},
  keywords     = {Rhodococcus equi,IMMUNOCOMPETENT PATIENT,pulmonary infection,extra-pulmonary infection,BRAIN-ABSCESS,PATHOGEN},
  language     = {eng},
  number       = {4},
  pages        = {271--275},
  title        = {Invasive infection with Rhodococcus equi : two case reports and review of literature},
  volume       = {65},
  year         = {2010},
}

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