Ghent University Academic Bibliography

Advanced

The effect of smoking on survival and bone loss of implants with a fluoride-modified surface: a 2-year retrospective analysis of 1106 implants placed in daily practice

STIJN VERVAEKE UGent, Bruno Collaert, Stefan Vandeweghe UGent, Jan Cosyn UGent, Ellen Deschepper UGent and Hugo De Bruyn UGent (2012) CLINICAL ORAL IMPLANTS RESEARCH. 23(6). p.758-766
abstract
Aim: To compare survival and peri-implant bone loss of implants with a fluoride-modified surface in smokers and nonsmokers. Materials and Methods: Patient files of all patients referred for implant treatment from November 2004 to 2007 were scrutinized. All implants were placed by the same experienced surgeon (BC). The only inclusion criterion was a follow-up time of at least 2 years. Implant survival and bone loss were assessed by an external calibrated examiner (SV) comparing digital peri-apical radiographs taken during recall visits with the post-operative ones. Implant success was determined according to the international success criteria (Albrektsson et al. 1986). Survival of implants installed in smokers and nonsmokers were compared using the log-rank test. Both non-parametric tests and fixed model analysis were adopted to evaluate bone loss in smokers and nonsmokers. Results: 1106 implants in 300 patients (186 females; 114 males) with a mean follow-up of 31 months (SD 7.15; range 24-58) were included. 19 implants in 17 patients failed, resulting in an overall survival rate of 98.3% on implant level and 94.6% on patient level. After a follow-up period of 2 years, the CSR was 96.7% and 99.1% with the patient and implant as statistical unit respectively. Implant survival was significantly higher for nonsmokers compared to smokers (implant level p = 0.025; patient level p = 0.017). The overall mean bone loss was 0.34 mm (n = 1076; SD 0.65; range 0.00-7.10). Smokers lost significantly more bone compared to nonsmokers in the maxilla (0.74 mm; SD 1.07 vs 0.33 mm; SD 0.65; p < 0.001), but not in the mandible (0.25mm; SD 0.65 vs 0.22mm; SD 0.50; p = 0.298). Conclusion: The present study is the first to compare peri-implant bone loss in smokers and nonsmokers from the time of implant insertion (baseline) to at least 2 years of follow-up. Implants with a fluoride-modified surface demonstrated a high survival rate and limited bone loss. However, smokers are at higher risk to experience implant failure and more prone to show peri-implant bone loss in the maxilla. Whether this bone loss is predicting future biological complications remains to be evaluated.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
implant success, bone loss, smoking, osseospeed implant, implant survival, dental implant, OSTEOBLAST GENE-EXPRESSION, TIOBLAST DENTAL IMPLANTS, MARGINAL BONE, LONG-TERM, CIGARETTE-SMOKING, TITANIUM IMPLANTS, FOLLOW-UP, EDENTULOUS MAXILLA, RISK-FACTORS, HABITS
journal title
CLINICAL ORAL IMPLANTS RESEARCH
Clin. Oral Implants Res.
volume
23
issue
6
pages
758 - 766
Web of Science type
Article
Web of Science id
000303119000016
JCR category
DENTISTRY, ORAL SURGERY & MEDICINE
JCR impact factor
3.433 (2012)
JCR rank
6/81 (2012)
JCR quartile
1 (2012)
ISSN
0905-7161
DOI
10.1111/j.1708-8208.2011.00353.x
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1186938
handle
http://hdl.handle.net/1854/LU-1186938
date created
2011-03-12 17:58:34
date last changed
2012-09-20 15:22:20
@article{1186938,
  abstract     = {Aim:  To compare survival and peri-implant bone loss of implants with a fluoride-modified surface in smokers and nonsmokers. 
Materials and Methods: Patient files of all patients referred for implant treatment from November 2004 to 2007 were scrutinized. All implants were placed by the same experienced surgeon (BC). The only inclusion criterion was a follow-up time of at least 2 years. Implant survival and bone loss were assessed by an external calibrated examiner (SV) comparing digital peri-apical radiographs taken during recall visits with the post-operative ones. Implant success was determined according to the international success criteria (Albrektsson et al. 1986). Survival of implants installed in smokers and nonsmokers were compared using the log-rank test. Both non-parametric tests and fixed model analysis were adopted to evaluate bone loss in smokers and nonsmokers.
Results: 1106 implants in 300 patients (186 females; 114 males) with a mean follow-up of 31 months (SD 7.15; range 24-58) were included. 19 implants in 17 patients failed, resulting in an overall survival rate of 98.3\% on implant level and 94.6\% on patient level. After a follow-up period of 2 years, the CSR was 96.7\% and 99.1\% with the patient and implant as statistical unit respectively. Implant survival was significantly higher for nonsmokers compared to smokers (implant level p = 0.025; patient level p = 0.017). The overall mean bone loss was 0.34 mm (n = 1076; SD 0.65; range 0.00-7.10). Smokers lost significantly more bone compared to nonsmokers in the maxilla (0.74 mm; SD 1.07 vs 0.33 mm; SD 0.65; p {\textlangle} 0.001), but not in the mandible (0.25mm; SD 0.65 vs 0.22mm; SD 0.50; p = 0.298). 
Conclusion: The present study is the first to compare peri-implant bone loss in smokers and nonsmokers from the time of implant insertion (baseline) to at least 2 years of follow-up. Implants with a fluoride-modified surface demonstrated a high survival rate and limited bone loss. However, smokers are at higher risk to experience implant failure and more prone to show peri-implant bone loss in the maxilla. Whether this bone loss is predicting future biological complications remains to be evaluated.},
  author       = {VERVAEKE, STIJN and Collaert, Bruno and Vandeweghe, Stefan and Cosyn, Jan and Deschepper, Ellen and De Bruyn, Hugo},
  issn         = {0905-7161},
  journal      = {CLINICAL ORAL IMPLANTS RESEARCH},
  keyword      = {implant success,bone loss,smoking,osseospeed implant,implant survival,dental implant,OSTEOBLAST GENE-EXPRESSION,TIOBLAST DENTAL IMPLANTS,MARGINAL BONE,LONG-TERM,CIGARETTE-SMOKING,TITANIUM IMPLANTS,FOLLOW-UP,EDENTULOUS MAXILLA,RISK-FACTORS,HABITS},
  language     = {eng},
  number       = {6},
  pages        = {758--766},
  title        = {The effect of smoking on survival and bone loss of implants with a fluoride-modified surface: a 2-year retrospective analysis of 1106 implants placed in daily practice},
  url          = {http://dx.doi.org/10.1111/j.1708-8208.2011.00353.x},
  volume       = {23},
  year         = {2012},
}

Chicago
Vervaeke, Stijn, Bruno Collaert, Stefan Vandeweghe, Jan Cosyn, Ellen Deschepper, and Hugo De Bruyn. 2012. “The Effect of Smoking on Survival and Bone Loss of Implants with a Fluoride-modified Surface: a 2-year Retrospective Analysis of 1106 Implants Placed in Daily Practice.” Clinical Oral Implants Research 23 (6): 758–766.
APA
Vervaeke, S., Collaert, B., Vandeweghe, S., Cosyn, J., Deschepper, E., & De Bruyn, H. (2012). The effect of smoking on survival and bone loss of implants with a fluoride-modified surface: a 2-year retrospective analysis of 1106 implants placed in daily practice. CLINICAL ORAL IMPLANTS RESEARCH, 23(6), 758–766.
Vancouver
1.
Vervaeke S, Collaert B, Vandeweghe S, Cosyn J, Deschepper E, De Bruyn H. The effect of smoking on survival and bone loss of implants with a fluoride-modified surface: a 2-year retrospective analysis of 1106 implants placed in daily practice. CLINICAL ORAL IMPLANTS RESEARCH. 2012;23(6):758–66.
MLA
Vervaeke, Stijn, Bruno Collaert, Stefan Vandeweghe, et al. “The Effect of Smoking on Survival and Bone Loss of Implants with a Fluoride-modified Surface: a 2-year Retrospective Analysis of 1106 Implants Placed in Daily Practice.” CLINICAL ORAL IMPLANTS RESEARCH 23.6 (2012): 758–766. Print.