Advanced search
1 file | 103.59 KB

Topography of the rabbit paranasal sinuses as a prerequisite to model human sinusitis

(2010) RHINOLOGY. 48(3). p.300-304
Author
Organization
Abstract
Background: Anatomical studies of the rabbit paranasal cavities are impelled by the increasing interest in the rabbit model to investigate human sinusitis. Although several such studies have already been performed, the topography of the rabbit dorsal conchal and maxillary sinuses is described ambiguously and the existence of the ethmoidal, frontal and sphenoidal sinuses is controversial. Methodology: The paranasal cavities were investigated using corrosion casting, gross and histological cross-sectioning, and micro-CT scanning of rabbit noses followed by computerized three-dimensional reconstruction. Results: Micro-CT scanning was most useful to illustrate the dorsal conchal sinus, the large maxillary sinus consisting of a dorsal and a ventral recess, and the sphenoidal sinus. All these sinuses are paired and symmetrical. A large connection is present between the dorsal conchal sinus and the maxillary sinus resulting in one large conchomaxillary cavity. The sphenoidal sinus lies most caudal and is surrounded by the presphenoid bone. The openings from the nasal cavity into the conchomaxillary cavity and the sphenoidal sinus are very small. Conclusions: The absence of frontal and ethmoidal sinuses in any of the rabbits examined is a major difference between the rabbit and human sinuses. The rabbit maxillary sinus seems most appropriate for experimental work.
Keywords
three-dimensional reconstruction, nasal cavity, micro-CT, rabbit, paranasal sinuses, MAXILLARY SINUS, FRONTAL-SINUS, ANIMAL-MODELS, BONE, OBLITERATION, NASAL

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 103.59 KB

Citation

Please use this url to cite or link to this publication:

Chicago
Casteleyn, Christophe, Pieter Cornillie, Astrid Hermens, Denis Van Loo, Luc Van Hoorebeke, Wim Van Den Broeck, and Paul Simoens. 2010. “Topography of the Rabbit Paranasal Sinuses as a Prerequisite to Model Human Sinusitis.” Rhinology 48 (3): 300–304.
APA
Casteleyn, C., Cornillie, P., Hermens, A., Van Loo, D., Van Hoorebeke, L., Van Den Broeck, W., & Simoens, P. (2010). Topography of the rabbit paranasal sinuses as a prerequisite to model human sinusitis. RHINOLOGY, 48(3), 300–304.
Vancouver
1.
Casteleyn C, Cornillie P, Hermens A, Van Loo D, Van Hoorebeke L, Van Den Broeck W, et al. Topography of the rabbit paranasal sinuses as a prerequisite to model human sinusitis. RHINOLOGY. 2010;48(3):300–4.
MLA
Casteleyn, Christophe, Pieter Cornillie, Astrid Hermens, et al. “Topography of the Rabbit Paranasal Sinuses as a Prerequisite to Model Human Sinusitis.” RHINOLOGY 48.3 (2010): 300–304. Print.
@article{1162202,
  abstract     = {Background: Anatomical studies of the rabbit paranasal cavities are impelled by the increasing interest in the rabbit model to investigate human sinusitis. Although several such studies have already been performed, the topography of the rabbit dorsal conchal and maxillary sinuses is described ambiguously and the existence of the ethmoidal, frontal and sphenoidal sinuses is controversial.
Methodology: The paranasal cavities were investigated using corrosion casting, gross and histological cross-sectioning, and micro-CT scanning of rabbit noses followed by computerized
three-dimensional reconstruction.
Results: Micro-CT scanning was most useful to illustrate the dorsal conchal sinus, the large maxillary sinus consisting of a dorsal and a ventral recess, and the sphenoidal sinus. All these
sinuses are paired and symmetrical. A large connection is present between the dorsal conchal sinus and the maxillary sinus resulting in one large conchomaxillary cavity. The sphenoidal sinus lies most caudal and is surrounded by the presphenoid bone. The openings from the nasal cavity into the conchomaxillary cavity and the sphenoidal sinus are very small.
Conclusions: The absence of frontal and ethmoidal sinuses in any of the rabbits examined is a major difference between the rabbit and human sinuses. The rabbit maxillary sinus seems most appropriate for experimental work.},
  author       = {Casteleyn, Christophe and Cornillie, Pieter and Hermens, Astrid and Van Loo, Denis and Van Hoorebeke, Luc and Van Den Broeck, Wim and Simoens, Paul},
  issn         = {0300-0729},
  journal      = {RHINOLOGY},
  keyword      = {three-dimensional reconstruction,nasal cavity,micro-CT,rabbit,paranasal sinuses,MAXILLARY SINUS,FRONTAL-SINUS,ANIMAL-MODELS,BONE,OBLITERATION,NASAL},
  language     = {eng},
  number       = {3},
  pages        = {300--304},
  title        = {Topography of the rabbit paranasal sinuses as a prerequisite to model human sinusitis},
  url          = {http://dx.doi.org/10.4193/Rhin09.193},
  volume       = {48},
  year         = {2010},
}

Altmetric
View in Altmetric
Web of Science
Times cited: