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Genetic counselling and testing for hereditary breast and ovarian cancer: the gent(le) approach

(1999) DISEASE MARKERS. 15(1-3). p.191-195
Author
Organization
Abstract
The counselling experience with 50 Flemish families in whom mutation analysis of the total coding region of the BRCA1 and BRCA2 gene has been initiated, is presented. Genetic testing for breast-ovarian cancer susceptibility is offered by a multidisciplinary team. During the counselling sessions, special attention is given to comprehensible and emotionally acceptable communication of genetic information and to the psychosocial evaluation of the counselee. The limitations of molecular testing and the controversy surrounding cancer prevention strategies are also discussed. The overall acceptance of mutation testing is high. Some of the-problems encountered are inaccuracy of the reported family history, poor retrieval of the medical records of affected family members and the reluctance of many patients to inform their relatives about the possibility of being tested.
Keywords
BRCA1, MUTATIONS, FAMILIES

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Citation

Please use this url to cite or link to this publication:

MLA
De Vos, M., et al. “Genetic Counselling and Testing for Hereditary Breast and Ovarian Cancer: The Gent(Le) Approach.” DISEASE MARKERS, vol. 15, no. 1–3, 1999, pp. 191–95, doi:10.1155/1999/809125.
APA
De Vos, M., Poppe, B., Delvaux, I., Mortier, G., Claes, K., Messiaen, L., & De Paepe, A. (1999). Genetic counselling and testing for hereditary breast and ovarian cancer: the gent(le) approach. DISEASE MARKERS, 15(1–3), 191–195. https://doi.org/10.1155/1999/809125
Chicago author-date
De Vos, M, Bruce Poppe, Isabelle Delvaux, Geert Mortier, Kathleen Claes, Ludwine Messiaen, and Anne De Paepe. 1999. “Genetic Counselling and Testing for Hereditary Breast and Ovarian Cancer: The Gent(Le) Approach.” DISEASE MARKERS 15 (1–3): 191–95. https://doi.org/10.1155/1999/809125.
Chicago author-date (all authors)
De Vos, M, Bruce Poppe, Isabelle Delvaux, Geert Mortier, Kathleen Claes, Ludwine Messiaen, and Anne De Paepe. 1999. “Genetic Counselling and Testing for Hereditary Breast and Ovarian Cancer: The Gent(Le) Approach.” DISEASE MARKERS 15 (1–3): 191–195. doi:10.1155/1999/809125.
Vancouver
1.
De Vos M, Poppe B, Delvaux I, Mortier G, Claes K, Messiaen L, et al. Genetic counselling and testing for hereditary breast and ovarian cancer: the gent(le) approach. DISEASE MARKERS. 1999;15(1–3):191–5.
IEEE
[1]
M. De Vos et al., “Genetic counselling and testing for hereditary breast and ovarian cancer: the gent(le) approach,” DISEASE MARKERS, vol. 15, no. 1–3, pp. 191–195, 1999.
@article{115012,
  abstract     = {{The counselling experience with 50 Flemish families in whom mutation analysis of the total coding region of the BRCA1 and BRCA2 gene has been initiated, is presented. 
Genetic testing for breast-ovarian cancer susceptibility is offered by a multidisciplinary team. During the counselling sessions, special attention is given to comprehensible and emotionally acceptable communication of genetic information and to the psychosocial evaluation of the counselee. The limitations of molecular testing and the controversy surrounding cancer prevention strategies are also discussed. 
The overall acceptance of mutation testing is high. Some of the-problems encountered are inaccuracy of the reported family history, poor retrieval of the medical records of affected family members and the reluctance of many patients to inform their relatives about the possibility of being tested.}},
  author       = {{De Vos, M and Poppe, Bruce and Delvaux, Isabelle and Mortier, Geert and Claes, Kathleen and Messiaen, Ludwine and De Paepe, Anne}},
  issn         = {{0278-0240}},
  journal      = {{DISEASE MARKERS}},
  keywords     = {{BRCA1,MUTATIONS,FAMILIES}},
  language     = {{eng}},
  number       = {{1-3}},
  pages        = {{191--195}},
  title        = {{Genetic counselling and testing for hereditary breast and ovarian cancer: the gent(le) approach}},
  url          = {{http://doi.org/10.1155/1999/809125}},
  volume       = {{15}},
  year         = {{1999}},
}

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