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Mitral valve leakage quantification by means of experimental and numerical flow modeling

(2010) ACTA MECHANICA SLOVACA. 14(2). p.18-25
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Abstract
Accurate quantification of mitral valve regurgitation (MR) is a challenging task in clinical cardiology. In order to develop and refine new algorithms for estimating the severity of MR using real-time 3D Doppler echocardiography (RT3DE), an experimental and numerical flow model have been designed and constructed. Using CAD, Rapid Prototyping Manufacturing (RPM) and five-axis milling technology, a hydraulic in vitro flow model, compatible for flow investigation with 2D normal speed Particle Image Velocimetry (PIV) and 2D Doppler Echocardiography. The same CAD model was used to conduct the Computational Fluid Dynamics (CFD) analysis. PIV, 2D Doppler Echocardiography and CFD results compare successfully in the upstream converging region and in the downstream turbulent regurgitated jet zone. These results are expected to improve the clinical assessment of mitral valve regurgitation severity by means of Doppler echocardiography.
Keywords
Particle image velocimetry, rapid prototyping modeling, 2D doppler echocardiography, mitral valve regurgitation, heart valve, comptational fluid dynamics

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Chicago
Vermeulen, Mathias, Benjamin Van Der Smissen, Tom Claessens, Rado Kaminsky, Patrick Segers, Pascal Verdonck, and Peter Van Ransbeeck. 2010. “Mitral Valve Leakage Quantification by Means of Experimental and Numerical Flow Modeling.” Acta Mechanica Slovaca 14 (2): 18–25.
APA
Vermeulen, Mathias, Van Der Smissen, B., Claessens, T., Kaminsky, R., Segers, P., Verdonck, P., & Van Ransbeeck, P. (2010). Mitral valve leakage quantification by means of experimental and numerical flow modeling. ACTA MECHANICA SLOVACA, 14(2), 18–25.
Vancouver
1.
Vermeulen M, Van Der Smissen B, Claessens T, Kaminsky R, Segers P, Verdonck P, et al. Mitral valve leakage quantification by means of experimental and numerical flow modeling. ACTA MECHANICA SLOVACA. 2010;14(2):18–25.
MLA
Vermeulen, Mathias, Benjamin Van Der Smissen, Tom Claessens, et al. “Mitral Valve Leakage Quantification by Means of Experimental and Numerical Flow Modeling.” ACTA MECHANICA SLOVACA 14.2 (2010): 18–25. Print.
@article{1149517,
  abstract     = {Accurate quantification of mitral valve regurgitation (MR) is a challenging task in clinical cardiology. In order to develop and refine new algorithms for estimating the severity of MR using real-time 3D Doppler echocardiography (RT3DE), an experimental and numerical flow model have been designed and constructed. Using CAD, Rapid Prototyping Manufacturing (RPM) and five-axis milling technology, a hydraulic in vitro flow model, compatible for flow investigation with 2D normal speed Particle Image Velocimetry (PIV) and 2D Doppler Echocardiography. The same CAD model was used to conduct the Computational Fluid Dynamics (CFD) analysis. PIV, 2D Doppler Echocardiography and CFD results compare successfully in the upstream converging region and in the downstream turbulent regurgitated jet zone. These results are expected to improve the clinical assessment of mitral valve regurgitation severity by means of Doppler echocardiography.},
  author       = {Vermeulen, Mathias and Van Der Smissen, Benjamin and Claessens, Tom and Kaminsky, Rado and Segers, Patrick and Verdonck, Pascal and Van Ransbeeck, Peter},
  issn         = {1335-2393},
  journal      = {ACTA MECHANICA SLOVACA},
  language     = {eng},
  number       = {2},
  pages        = {18--25},
  title        = {Mitral valve leakage quantification by means of experimental and numerical flow modeling},
  volume       = {14},
  year         = {2010},
}