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Synthesis of C-6-substituted uridine phosphonates through aerobic ligand-free Suzuki-Miyaura cross-coupling

Radim Nencka UGent, Davy Sinnaeve UGent, Izet Karalic UGent, José Martins UGent and Serge Van Calenbergh UGent (2010) ORGANIC & BIOMOLECULAR CHEMISTRY. 8(22). p.5234-5246
abstract
An efficient protocol for the construction of C-6-(hetero)aryl-substituted uridine phosphonate analogues utilizing an aerobic, ligand-free Suzuki-Miyaura cross-coupling reaction of a 6-iodo-precursor in aqueous media has been established. The method presents a modular approach toward the target compounds as demonstrated by the synthesis of a small library comprising 14 novel nucleoside phosphonates.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
INHIBITORS, CHEMISTRY, DERIVATIVES, PALLADIUM, WATER, NUCLEOSIDES, CONFORMATIONAL-ANALYSIS, MAGNETIC-RESONANCE, SUGAR RING, NUCLEOTIDE ANALOG
journal title
ORGANIC & BIOMOLECULAR CHEMISTRY
Org. Biomol. Chem.
volume
8
issue
22
pages
5234 - 5246
Web of Science type
Article
Web of Science id
000283602000027
JCR category
CHEMISTRY, ORGANIC
JCR impact factor
3.451 (2010)
JCR rank
12/56 (2010)
JCR quartile
1 (2010)
ISSN
1477-0520
DOI
10.1039/c0ob00061b
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1126881
handle
http://hdl.handle.net/1854/LU-1126881
date created
2011-02-04 10:30:25
date last changed
2016-12-19 15:45:26
@article{1126881,
  abstract     = {An efficient protocol for the construction of C-6-(hetero)aryl-substituted uridine phosphonate analogues utilizing an aerobic, ligand-free Suzuki-Miyaura cross-coupling reaction of a 6-iodo-precursor in aqueous media has been established. The method presents a modular approach toward the target compounds as demonstrated by the synthesis of a small library comprising 14 novel nucleoside phosphonates.},
  author       = {Nencka, Radim and Sinnaeve, Davy and Karalic, Izet and Martins, Jos{\'e} and Van Calenbergh, Serge},
  issn         = {1477-0520},
  journal      = {ORGANIC \& BIOMOLECULAR CHEMISTRY},
  keyword      = {INHIBITORS,CHEMISTRY,DERIVATIVES,PALLADIUM,WATER,NUCLEOSIDES,CONFORMATIONAL-ANALYSIS,MAGNETIC-RESONANCE,SUGAR RING,NUCLEOTIDE ANALOG},
  language     = {eng},
  number       = {22},
  pages        = {5234--5246},
  title        = {Synthesis of C-6-substituted uridine phosphonates through aerobic ligand-free Suzuki-Miyaura cross-coupling},
  url          = {http://dx.doi.org/10.1039/c0ob00061b},
  volume       = {8},
  year         = {2010},
}

Chicago
Nencka, Radim, Davy Sinnaeve, Izet Karalic, José Martins, and Serge Van Calenbergh. 2010. “Synthesis of C-6-substituted Uridine Phosphonates Through Aerobic Ligand-free Suzuki-Miyaura Cross-coupling.” Organic & Biomolecular Chemistry 8 (22): 5234–5246.
APA
Nencka, R., Sinnaeve, D., Karalic, I., Martins, J., & Van Calenbergh, S. (2010). Synthesis of C-6-substituted uridine phosphonates through aerobic ligand-free Suzuki-Miyaura cross-coupling. ORGANIC & BIOMOLECULAR CHEMISTRY, 8(22), 5234–5246.
Vancouver
1.
Nencka R, Sinnaeve D, Karalic I, Martins J, Van Calenbergh S. Synthesis of C-6-substituted uridine phosphonates through aerobic ligand-free Suzuki-Miyaura cross-coupling. ORGANIC & BIOMOLECULAR CHEMISTRY. 2010;8(22):5234–46.
MLA
Nencka, Radim, Davy Sinnaeve, Izet Karalic, et al. “Synthesis of C-6-substituted Uridine Phosphonates Through Aerobic Ligand-free Suzuki-Miyaura Cross-coupling.” ORGANIC & BIOMOLECULAR CHEMISTRY 8.22 (2010): 5234–5246. Print.