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Enantiomeric separation of some amino acids and derivatives by capillary electrophoresis with 18-crown-6-tetracarboxylic acid as chiral selector

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Abstract
A number of amino acids and derivatives, bought or synthesized, were analyzed by capillary electrophoresis (CE:) with optical active 18-crown-6-tetracarboxylic acid (18C6H(4)) as chiral selector. Besides the primary interaction: i.e., inclusion of the protonated primary amino function in the crown ether cavity, a second interaction mechanism between the substituents on the racemates and the carboxylic acid functions on the crown ether to enhance or suppress enantioselectivity. In certain cases, very high resolutions (R-s > 5) were noted, e.g., R-s 30 for serine benzyl ester. (C) 1999 John Wiley & Sons, Inc.
Keywords
capillary electrophoresis, enantioselective separations, 18-crown-6-tetracarboxylic acid (18C6H(4)), amino acids and derivatives, ZONE ELECTROPHORESIS, CYCLODEXTRINS, VANCOMYCIN

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MLA
Verleysen, Katleen, and Patrick Sandra. “Enantiomeric Separation of Some Amino Acids and Derivatives by Capillary Electrophoresis with 18-Crown-6-Tetracarboxylic Acid as Chiral Selector.” JOURNAL OF MICROCOLUMN SEPARATIONS, vol. 11, no. 1, 1999, pp. 37–43, doi:10.1002/(SICI)1520-667X(1999)11:1<37::AID-MCS5>3.0.CO;2-X.
APA
Verleysen, K., & Sandra, P. (1999). Enantiomeric separation of some amino acids and derivatives by capillary electrophoresis with 18-crown-6-tetracarboxylic acid as chiral selector. JOURNAL OF MICROCOLUMN SEPARATIONS, 11(1), 37–43. https://doi.org/10.1002/(SICI)1520-667X(1999)11:1<37::AID-MCS5>3.0.CO;2-X
Chicago author-date
Verleysen, Katleen, and Patrick Sandra. 1999. “Enantiomeric Separation of Some Amino Acids and Derivatives by Capillary Electrophoresis with 18-Crown-6-Tetracarboxylic Acid as Chiral Selector.” JOURNAL OF MICROCOLUMN SEPARATIONS 11 (1): 37–43. https://doi.org/10.1002/(SICI)1520-667X(1999)11:1<37::AID-MCS5>3.0.CO;2-X.
Chicago author-date (all authors)
Verleysen, Katleen, and Patrick Sandra. 1999. “Enantiomeric Separation of Some Amino Acids and Derivatives by Capillary Electrophoresis with 18-Crown-6-Tetracarboxylic Acid as Chiral Selector.” JOURNAL OF MICROCOLUMN SEPARATIONS 11 (1): 37–43. doi:10.1002/(SICI)1520-667X(1999)11:1<37::AID-MCS5>3.0.CO;2-X.
Vancouver
1.
Verleysen K, Sandra P. Enantiomeric separation of some amino acids and derivatives by capillary electrophoresis with 18-crown-6-tetracarboxylic acid as chiral selector. JOURNAL OF MICROCOLUMN SEPARATIONS. 1999;11(1):37–43.
IEEE
[1]
K. Verleysen and P. Sandra, “Enantiomeric separation of some amino acids and derivatives by capillary electrophoresis with 18-crown-6-tetracarboxylic acid as chiral selector,” JOURNAL OF MICROCOLUMN SEPARATIONS, vol. 11, no. 1, pp. 37–43, 1999.
@article{112195,
  abstract     = {{A number of amino acids and derivatives, bought or synthesized, were analyzed by capillary electrophoresis (CE:) with optical active 18-crown-6-tetracarboxylic acid (18C6H(4)) as chiral selector. Besides the primary interaction: i.e., inclusion of the protonated primary amino function in the crown ether cavity, a second interaction mechanism between the substituents on the racemates and the carboxylic acid functions on the crown ether to enhance or suppress enantioselectivity. In certain cases, very high resolutions (R-s > 5) were noted, e.g., R-s 30 for serine benzyl ester. (C) 1999 John Wiley & Sons, Inc.}},
  author       = {{Verleysen, Katleen and Sandra, Patrick}},
  issn         = {{1040-7685}},
  journal      = {{JOURNAL OF MICROCOLUMN SEPARATIONS}},
  keywords     = {{capillary electrophoresis,enantioselective separations,18-crown-6-tetracarboxylic acid (18C6H(4)),amino acids and derivatives,ZONE ELECTROPHORESIS,CYCLODEXTRINS,VANCOMYCIN}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{37--43}},
  title        = {{Enantiomeric separation of some amino acids and derivatives by capillary electrophoresis with 18-crown-6-tetracarboxylic acid as chiral selector}},
  url          = {{http://doi.org/10.1002/(SICI)1520-667X(1999)11:1<37::AID-MCS5>3.0.CO;2-X}},
  volume       = {{11}},
  year         = {{1999}},
}

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