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Reliability and construct validity of ultrasonography of soft tissue and destructive changes in erosive osteoarthritis of the interphalangeal finger joints: a comparison with MRI

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Abstract
OBJECTIVES:To study the reliability and construct validity of ultrasound in interphalangeal finger joints affected by erosive osteoarthritis (EOA) and non-EOA with MRI as the reference method. METHODS: 252 joints were examined by ultrasound, conventional radiography and clinical examination. Ultrasound was performed using a high-frequency linear transducer (12×18 MHz). On the same day, magnetic resonance images of 112 joints were obtained on a 3.0 T magnetic resonance unit. The ultrasound and MRI images were re-read independently by other readers unaware of the diagnosis, clinical and other imaging findings. Interobserver reliability was calculated by the percentage of exact agreement obtained and κ statistics. With MRI as the reference method, the sensitivity and specificity of ultrasound in detecting structural (bone erosions and osteophytes) and soft tissue (effusion and grey-scale synovitis) changes in EOA were calculated. RESULTS: Ultrasound and MRI were found to be more sensitive in detecting erosions than conventional radiography in EOA. A high agreement between ultrasound and MRI in the assessment of bone erosions (77.7%), osteophytes (75.9%) and synovitis (86.5%) was present. A high percentage of inflammatory changes was found in EOA, and in smaller amount in non-EOA, both confirmed by MRI. Good interobserver reliability of ultrasound was obtained for all variables (all median κ >0.8). CONCLUSION: Grey-scale ultrasound proved to be a reliable and valid imaging technique to assess erosions and soft tissue changes, compared with MRI as a reference method in EOA.
Keywords
PATHOLOGY, RHEUMATOID-ARTHRITIS, DEFINITIONS, HAND, SCORING SYSTEM

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Chicago
Wittoek, Ruth, Lennart Jans, Valerie Lambrecht, PHILIPPE CARRON, Koenraad Verstraete, and August Verbruggen. 2011. “Reliability and Construct Validity of Ultrasonography of Soft Tissue and Destructive Changes in Erosive Osteoarthritis of the Interphalangeal Finger Joints: a Comparison with MRI.” Annals of the Rheumatic Diseases 70 (2): 278–283.
APA
Wittoek, R., Jans, L., Lambrecht, V., CARRON, P., Verstraete, K., & Verbruggen, A. (2011). Reliability and construct validity of ultrasonography of soft tissue and destructive changes in erosive osteoarthritis of the interphalangeal finger joints: a comparison with MRI. ANNALS OF THE RHEUMATIC DISEASES, 70(2), 278–283.
Vancouver
1.
Wittoek R, Jans L, Lambrecht V, CARRON P, Verstraete K, Verbruggen A. Reliability and construct validity of ultrasonography of soft tissue and destructive changes in erosive osteoarthritis of the interphalangeal finger joints: a comparison with MRI. ANNALS OF THE RHEUMATIC DISEASES. 2011;70(2):278–83.
MLA
Wittoek, Ruth, Lennart Jans, Valerie Lambrecht, et al. “Reliability and Construct Validity of Ultrasonography of Soft Tissue and Destructive Changes in Erosive Osteoarthritis of the Interphalangeal Finger Joints: a Comparison with MRI.” ANNALS OF THE RHEUMATIC DISEASES 70.2 (2011): 278–283. Print.
@article{1111303,
  abstract     = {OBJECTIVES:To study the reliability and construct validity of ultrasound in interphalangeal finger joints affected by erosive osteoarthritis (EOA) and non-EOA with MRI as the reference method.
METHODS: 252 joints were examined by ultrasound, conventional radiography and clinical examination. Ultrasound was performed using a high-frequency linear transducer (12{\texttimes}18 MHz). On the same day, magnetic resonance images of 112 joints were obtained on a 3.0 T magnetic resonance unit. The ultrasound and MRI images were re-read independently by other readers unaware of the diagnosis, clinical and other imaging findings. Interobserver reliability was calculated by the percentage of exact agreement obtained and \ensuremath{\kappa} statistics. With MRI as the reference method, the sensitivity and specificity of ultrasound in detecting structural (bone erosions and osteophytes) and soft tissue (effusion and grey-scale synovitis) changes in EOA were calculated.
RESULTS: Ultrasound and MRI were found to be more sensitive in detecting erosions than conventional radiography in EOA. A high agreement between ultrasound and MRI in the assessment of bone erosions (77.7\%), osteophytes (75.9\%) and synovitis (86.5\%) was present. A high percentage of inflammatory changes was found in EOA, and in smaller amount in non-EOA, both confirmed by MRI. Good interobserver reliability of ultrasound was obtained for all variables (all median \ensuremath{\kappa} {\textrangle}0.8).
CONCLUSION: Grey-scale ultrasound proved to be a reliable and valid imaging technique to assess erosions and soft tissue changes, compared with MRI as a reference method in EOA.},
  author       = {Wittoek, Ruth and Jans, Lennart and Lambrecht, Valerie and CARRON, PHILIPPE and Verstraete, Koenraad and Verbruggen, August},
  issn         = {0003-4967},
  journal      = {ANNALS OF THE RHEUMATIC DISEASES},
  language     = {eng},
  number       = {2},
  pages        = {278--283},
  title        = {Reliability and construct validity of ultrasonography of soft tissue and destructive changes in erosive osteoarthritis of the interphalangeal finger joints: a comparison with MRI},
  url          = {http://dx.doi.org/10.1136/ard.2010.134932},
  volume       = {70},
  year         = {2011},
}

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