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No genetics without epigenetics? No biology without systems biology? On the meaning of a relational viewpoint in a complex account of living systems

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Abstract
In this article, we propose to reflect on the meaning of complexity in relation to current biology, and in particular, in relation to current systems biological developments by considering them as confronting biology with the idea of a complex part–whole determination of living systems, that is contextual as well as stratified. We attempt to trace as clearly as possible the abstract core of the idea of parts and wholes that is at stake in this contextual determination. In doing so, we have found inspiration in Kant’s view on living systems. We argue that Kant’s transcendental viewpoint can be relevantly actualized and extrapolated as a relational account of living systems, and will explore its ramifications starting from a multilevel view of living systems.
Keywords
epigenetics, Kant, systems biology, relational epistemology, complexity, contextual determination, multi-level determination, parts and wholes

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Chicago
Van de Vijver, Gertrudis. 2009. “No Genetics Without Epigenetics? No Biology Without Systems Biology? On the Meaning of a Relational Viewpoint in a Complex Account of Living Systems.” Annals of the New York Academy of Science 1178: 305–317.
APA
Van de Vijver, G. (2009). No genetics without epigenetics? No biology without systems biology? On the meaning of a relational viewpoint in a complex account of living systems. ANNALS OF THE NEW YORK ACADEMY OF SCIENCE, 1178, 305–317.
Vancouver
1.
Van de Vijver G. No genetics without epigenetics? No biology without systems biology? On the meaning of a relational viewpoint in a complex account of living systems. ANNALS OF THE NEW YORK ACADEMY OF SCIENCE. 2009;1178:305–17.
MLA
Van de Vijver, Gertrudis. “No Genetics Without Epigenetics? No Biology Without Systems Biology? On the Meaning of a Relational Viewpoint in a Complex Account of Living Systems.” ANNALS OF THE NEW YORK ACADEMY OF SCIENCE 1178 (2009): 305–317. Print.
@article{1104332,
  abstract     = {In this article, we propose to reflect on the meaning of complexity in relation to current biology, and in particular, in relation to current systems biological developments by considering them as confronting biology with the idea of a complex part--whole determination of living systems, that is contextual as well as stratified. We attempt to trace
as clearly as possible the abstract core of the idea of parts and wholes that is at stake in this contextual determination. In doing so, we have found inspiration in Kant{\textquoteright}s view
on living systems. We argue that Kant{\textquoteright}s transcendental viewpoint can be relevantly actualized and extrapolated as a relational account of living systems, and will explore its
ramifications starting from a multilevel view of living systems.},
  author       = {Van de Vijver, Gertrudis},
  isbn         = {9781573317658},
  issn         = {0077-8923},
  journal      = {ANNALS OF THE NEW YORK ACADEMY OF SCIENCE},
  keyword      = {epigenetics,Kant,systems biology,relational epistemology,complexity,contextual determination,multi-level determination,parts and wholes},
  language     = {eng},
  pages        = {305--317},
  title        = {No genetics without epigenetics? No biology without systems biology? On the meaning of a relational viewpoint in a complex account of living systems},
  url          = {http://dx.doi.org/10.1111/j.1749-6632.2009.05010.x},
  volume       = {1178},
  year         = {2009},
}

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