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Hyperimitation of actions is related to reduced understanding of others' minds in autism spectrum conditions

Stephanie Spengler, Geoffrey Bird and Marcel Brass UGent (2010) BIOLOGICAL PSYCHIATRY. 68(12). p.1148-1155
abstract
Background: Anecdotal evidence has noted that individuals with autism spectrum conditions (ASC) frequently exhibit heightened spontaneous imitative behavior, with symptoms of echolalia and echopraxia. This is contrasted by empiric reports that ASC results in decreased imitation and an underlying deficit in the mirror system, leading to impaired social understanding. Thus, it remains unclear whether automatic imitation is enhanced in ASC and how this is related to poorer social abilities. Methods: This study investigated spontaneous imitation in 18 high-functioning adults with ASC and 18 age-and IQ-matched control participants during a simple imitation inhibition task. Mentalizing was experimentally assessed in the same participants using both behavioral and functional magnetic resonance imaging measures, as was social interaction using an observational measure. Results: Individuals with ASC showed increased imitation of hand actions compared with control participants and this was associated with reduced mentalizing and poorer reciprocal social interaction abilities. In the functional magnetic resonance imaging mentalizing paradigm, ASC participants with increased imitation scores showed less brain activation in areas often found to be active in mental state attribution, namely the medial prefrontal cortex and temporoparietal junction. Conclusions: The results confirm the presence of hyperimitation in ASC, which is accompanied by reduced social cognition, suggesting that a general imitation impairment and a global mirror system deficit are absent. These findings offer an explanation for echopractic features based on theories of atypical functioning of top-down modulation processes in autism.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
MENTAL STATE ATTRIBUTION, ASPERGER-SYNDROME, MIRROR-NEURON SYSTEM, SOCIAL COGNITION, DISORDERS, IMITATION, INDIVIDUALS, MECHANISMS, RESPONSES, METAANALYSIS
journal title
BIOLOGICAL PSYCHIATRY
Biol. Psychiatry
volume
68
issue
12
pages
1148 - 1155
Web of Science type
Article
Web of Science id
000285389000012
JCR category
PSYCHIATRY
JCR impact factor
8.674 (2010)
JCR rank
4/126 (2010)
JCR quartile
1 (2010)
ISSN
0006-3223
DOI
10.1016/j.biopsych.2010.09.017
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1100853
handle
http://hdl.handle.net/1854/LU-1100853
date created
2011-01-15 18:07:43
date last changed
2017-07-24 13:31:08
@article{1100853,
  abstract     = {Background: Anecdotal evidence has noted that individuals with autism spectrum conditions (ASC) frequently exhibit heightened spontaneous imitative behavior, with symptoms of echolalia and echopraxia. This is contrasted by empiric reports that ASC results in decreased imitation and an underlying deficit in the mirror system, leading to impaired social understanding. Thus, it remains unclear whether automatic imitation is enhanced in ASC and how this is related to poorer social abilities.
Methods: This study investigated spontaneous imitation in 18 high-functioning adults with ASC and 18 age-and IQ-matched control participants during a simple imitation inhibition task. Mentalizing was experimentally assessed in the same participants using both behavioral and functional magnetic resonance imaging measures, as was social interaction using an observational measure.
Results: Individuals with ASC showed increased imitation of hand actions compared with control participants and this was associated with reduced mentalizing and poorer reciprocal social interaction abilities. In the functional magnetic resonance imaging mentalizing paradigm, ASC participants with increased imitation scores showed less brain activation in areas often found to be active in mental state attribution, namely the medial prefrontal cortex and temporoparietal junction.
Conclusions: The results confirm the presence of hyperimitation in ASC, which is accompanied by reduced social cognition, suggesting that a general imitation impairment and a global mirror system deficit are absent. These findings offer an explanation for echopractic features based on theories of atypical functioning of top-down modulation processes in autism.},
  author       = {Spengler, Stephanie and Bird, Geoffrey and Brass, Marcel},
  issn         = {0006-3223},
  journal      = {BIOLOGICAL PSYCHIATRY},
  keyword      = {MENTAL STATE ATTRIBUTION,ASPERGER-SYNDROME,MIRROR-NEURON SYSTEM,SOCIAL COGNITION,DISORDERS,IMITATION,INDIVIDUALS,MECHANISMS,RESPONSES,METAANALYSIS},
  language     = {eng},
  number       = {12},
  pages        = {1148--1155},
  title        = {Hyperimitation of actions is related to reduced understanding of others' minds in autism spectrum conditions},
  url          = {http://dx.doi.org/10.1016/j.biopsych.2010.09.017},
  volume       = {68},
  year         = {2010},
}

Chicago
Spengler, Stephanie, Geoffrey Bird, and Marcel Brass. 2010. “Hyperimitation of Actions Is Related to Reduced Understanding of Others’ Minds in Autism Spectrum Conditions.” Biological Psychiatry 68 (12): 1148–1155.
APA
Spengler, Stephanie, Bird, G., & Brass, M. (2010). Hyperimitation of actions is related to reduced understanding of others’ minds in autism spectrum conditions. BIOLOGICAL PSYCHIATRY, 68(12), 1148–1155.
Vancouver
1.
Spengler S, Bird G, Brass M. Hyperimitation of actions is related to reduced understanding of others’ minds in autism spectrum conditions. BIOLOGICAL PSYCHIATRY. 2010;68(12):1148–55.
MLA
Spengler, Stephanie, Geoffrey Bird, and Marcel Brass. “Hyperimitation of Actions Is Related to Reduced Understanding of Others’ Minds in Autism Spectrum Conditions.” BIOLOGICAL PSYCHIATRY 68.12 (2010): 1148–1155. Print.